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IVAL-BHTC Hepatocyte Workshop
IVAL Boston Hepatocyte Technology Center
389 Main Street, Malden, MA
IVAL-BHTC Hepatocyte Workshop
November 3rd and 4th, 2014
Hands-on laboratory training on thawing, recovery, and culturing cryopreserved
human and animal hepatocytes
About the workshop
Workshop Agenda:
IVAL BHTC is committed to the provision of hands on
training on the application of cryopreserved human
and animal hepatocytes in industrial and academic
research.
Monday, November 3rd, 9:00 am – 4:30 pm
Workshop participants will learn expert hepatocyte
handling techniques that will increase their success in
hepatocyte-based research. The knowledge shared at
our workshops has been rated top-notch by previous
attendees, from novice to experienced hepatocyte
users.
In addition to improving hepatocyte handling
techniques, the workshop includes a presentation by
Dr. Albert P. Li, an internationally renowned expert in
hepatocyte technologies. Dr. Li will provide a review of
state-of-the art science and technology surrounding
the use of cryopreserved hepatocytes in drug
development and biomedical research.
Working with cryopreserved hepatocytes

Thawing, counting, plating and Matrigel
overlaying of cryopreserved human and animal
hepatocytes

Handling OnDemand™ pre-plated
cryopreserved human hepatocytes

Lecture: New developments in hepatocytes
cryopreservation and applications in drug
development (Dr. Albert P. Li)

Group discussion
Tuesday, November 4th, 8:00 am – 9:30 am
Morphology evaluation and discussion



Morphology evaluation of cultured hepatocytes
Troubleshooting results
Group discussion
At right: Workshop participants review and
discuss cell morphology and confluency
from their plating exercise.
In Vitro ADMET Laboratories | 9221 Rumsey Road | Columbia, MD 21045
[email protected] (410) 869-9037
www.invitroadmet.com
IVAL-BHTC Hepatocyte Workshop
November 3rd and 4th, 2014
Page |2
Faculty
Albert P. Li, Ph.D.
Dr. Li is the President, CEO
and co-founder of In Vitro
ADMET Laboratories LLC.
His research is focused on
the development and
application of humanbased in vitro experimental
models, especially primary
cultured human
hepatocytes, in the accurate assessment of human drug
properties including metabolic fate, drug-drug
interactions and drug toxicity. Dr. Li was one of the first
scientists to successfully cryopreserve human
hepatocytes to retain properties of freshly isolated
cells, and the inventor of the patented Integrated
Discrete Multiple Organ Co-culture (IdMOC) system,
which allows cells from multiple organs to be
interconnected to emulate an entire organism. Dr. Li
has published approximately 160 research papers/book
chapters/reviews and edited/co-edited 6 books in
toxicology, drug metabolism, and cell biology.
Kirsten Amaral, MS
Dr. Li will be assisted by
Kirsten Amaral, Director of
Laboratory Operations at
IVAL’s Boston Hepatocyte
Technology Center, and
technical
expert
in
isolating, cryopreserving
and culturing human and
animal hepatocytes. Ms.
Amaral has a master’s degree in toxicology and over 10
years of hands-on laboratory experience with
hepatocytes.
Workshop Registration fee: $485 (Early bird registration: $435 by Oct 17th)
Fee includes all workshop materials. All participants will receive a special savings on their next order of IVAL products
Sign up for both November events and save $170!



Hepatocyte Workshop (Monday, full day, Tuesday morning): regularly $485; by Oct 17th: $435
Tox Course (Tuesday and Wednesday): regularly $485; by Oct 17th: $435
Workshop and Course combined: regularly $800; by Oct 17th: $700
Workshop space is limited and will be assigned on a first-come, first-served basis.
In Vitro ADMET Laboratories | 9221 Rumsey Road | Columbia, MD 21045
[email protected] (410) 869-9037
www.invitroadmet.com
IVAL-BHTC Hepatocyte Workshop
November 3rd, 2014
Page |3
General Information
The IVAL Boston Hepatocyte Training Center
(IVAL-BHTC) is conveniently located in
downtown Malden, Massachusetts, USA. The
facility is within walking distance from the
Massachusetts Bay Transportation Authority.
www.mbta.com. Please reference the map
insert.
Directions for mass transit: take the Orange line
to Malden Center. When exiting the Malden
Center station, cross Commercial Street at the
light. This will put you directly in front of the
Malden Government Center. As you face the
building, turn left and walk to Pleasant Street
and take a right. Follow Pleasant Street to Main
Street. We are across the Main Street at the
“City Center” Building – 389 Main Street, 3rd
Floor, Malden, MA.
Parking: Jackson Street Garage, located on
Jackson Street between Centre Street and
Exchange Street or CBD Garage located on
Middlesex Street, between Centre Street and
Exchange Street, Malden MA 02148.
Parking Rates:
Per Hour: $2.00
Daily Rate: $18.00
Early Bird: $6.00 (entry before 9:00 AM, exit
before7:00 PM)
Payment: Payment may be made by check or
credit card. Checks should be made in US
dollars, payable to “In Vitro ADMET Laboratories,
LLC. “
Submit your completed registration form and
preferred method of payment to Nola Mahaney:
[email protected] or
Mail: IVAL, LLC;
9221 Rumsey Road, Suite # 8,
Columbia, MD 21045, USA
FAX: (410) 869-9034.
Cancellation Policy: All cancellations are
subjected to a $100.00 cancellation fee. Greater
than 30 days, 100% refund (less cancellation
fee). Less than 30 days, no refund, but
registration may be transferred to another
person. All refund requests must be in writing.
All refunds will be issued after the meeting has
occurred. No refunds requests will be accepted
after November 3rd, 2014. Please submit
cancellation and refund requests including
registration transfer details to: Fax: 410-8699034; E-mail: [email protected]
Academic/Government participants will receive a
50% discount.
A larger version of this map is available on request
Hotel Accommodations:
We recommend Hyatt Place Boston/Medford:
116 Riverside Avenue
Medford, Massachusetts, USA, 02155
Tel: +1 781 395 8500
http://bostonmedford.place.hyatt.com
They have shuttle service to the T stops on an asneeded basis from 7:30 am-9:00 pm each day.
In Vitro ADMET Laboratories | 9221 Rumsey Road | Columbia, MD 21045
[email protected] (410) 869-9037
www.invitroadmet.com
IVAL-BHTC Hepatocyte Workshop
November 3rd, 2014
Page |4
Registration Information
To register, please fill out the following form and submit with
your selected form of payment by November 3rd, 2014. Please
note: seating is limited and will be assigned on a first-come,
first-served basis. For multiple registrations, please provide
the following information for each person.
Academic/Government participants will receive a 50%
discount.
EARLYBIRD DISCOUNT: 10% off your total if you
register by October 17th.
Please check:
Preferred form of payment:
PO Number: _______________________________
Credit Card (AmEx, Visa, MC): __________________
Number: ________________________________
Security Code: ___________________________
Name on the Card: ________________________
 November Hepatocyte Workshop: (Monday
Expiration Date: __________________________
(full day) and Tuesday (am), Nov 3rd and 4th)
$485 per person; $435 by Oct 17th
Total Amount: $_____________________________
 Toxicology and Drug Development short
Signature: _________________________________
course registration: (Tuesday and
Wednesday, Nov 4th and 5th) $485 per
person; $435 by Oct 17th
Billing Address: _____________________________
 Both workshop and course: $800 per person
(Save $170); $700 by Oct 17th
(Please print legibly)
__________________________________________
__________________________________________
Billing Contact Name / Phone Number:
__________________________________________
Name: ___________________________________
__________________________________________
Job Title: _________________________________
Company: ________________________________
Address 1: ________________________________
Address 2: ________________________________
City / ST / Zip: ______________________________
Submit this completed form to:
Email: Nola Mahaney, [email protected]
Fax: (410)-869-9034
Mail: IVAL, LLC;
9221 Rumsey Road, Suite # 8,
Columbia, MD 21045, USA
E-mail: __________________________________
Phone: __________________________________
In Vitro ADMET Laboratories | 9221 Rumsey Road | Columbia, MD 21045
[email protected] (410) 869-9037
www.invitroadmet.com