1. health and fitness

Immune Checkpoint Inhibitors Market Regulations and
Competitive Landscape Outlook to 2027
April 2017
Report Id : REP-GB-3326
Status : Ongoing
Category : Healthcare, Pharmaceuticals & Medical Devices
©2015 Future Market Insights, All Rights Reserved
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Immune Checkpoint Inhibitors Market Regulations and Competitive
Landscape Outlook to 2027
Cancer is the leading cause of death worldwide and hence offers a lot of unmet research areas yet to be
targeted. The field of oncology is wide comprising a varied type of application area. The focus of
researchers is gradually shifting towards the immunotherapies. The immunotherapy makes the use of
body’s own components to fight cancer. Immune checkpoints are molecules that stimulate or inhibit the
immune cells. Yervoy was the first drug launched in the immune checkpoint inhibitors domain. This anitCTLA-4 drug was followed by many other drugs such as Keytruda and Opdivo. Besides these molecules
there are several others under clinical development. There is an ongoing competition between the
immune checkpoint inhibitors market contributors to emerge as a leader.
Immune Checkpoint Inhibitors Market: Drivers and Restraints
The immune checkpoint inhibitors market is driven by the number of research developments undertaken
by industry contributors as well as academic institutes. The immune checkpoint inhibitors market is
experiencing a lot of collaborations wherein companies are combining their core competencies to fasten
their research programs. For instance, Merck known as MSD outside the U.S. and Canada along with
Dynavax Technologies Corporation are investigating the potential synergistic effects by combining
Dynavax's SD-101 with two of Merck’s immunotherapies Keytruda and MK-1966.
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Immune Checkpoint Inhibitors Market Regulations and Competitive
Landscape Outlook to 2027
Immune Checkpoint Inhibitors Market: Overview
The immune checkpoint inhibitor market is driven by the need to address the rising rate of cancer
prevalence thereby affecting the country healthcare cost. In UK, lung cancer is the leading cause of
cancer related death. The survival rate past five years has only being 9% after the person is diagnosed
with lung cancer. The new form of immunotherapy based on the inhibition of programmed death-ligand 1
(PD-L1) and programmed death-1 (PD-1) receptors has shown hope as a therapy option for lung cancer.
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Immune Checkpoint Inhibitors Market: Region-wise Outlook
In terms of geography, immune checkpoint inhibitors market has been divided into five regions including
North- America, Asia- Pacific and Middle-East & Africa, Latin America and Europe. The number of clinical
trials and research funding is relatively high in North America, making it the dominant region in terms of
revenue in the immune checkpoint inhibitors market. In September 2014, Merck received accelerated
FDA approval for its Keytruda molecule to treat patient with advanced melanoma. The company is
forming global alliances with other companies to co-develop
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Immune Checkpoint Inhibitors Market Regulations and Competitive
Landscape Outlook to 2027
immnuo-oncology research and expand its oncology business.
Asia Pacific is the fastest growing region in the immune checkpoint inhibitors market as there are number
of research collaborations of international players with companies from this region. For instance, BristolMyers Squibb received Japanese approval for Opdivo in 2014, through partnership with Ono
Pharmaceuticals.
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Immune Checkpoint Inhibitors Market: Key Market Participants
Some of the market contributors to the immune checkpoint inhibitors market are Bristol-Myers
Squibb, Merck & Co., Inc., Roche, AstraZeneca, Merck KGaA, Ono Pharmaceutical Co., Ltd., Novartis
International AG, Juno Therapeutics and Kite Pharma.
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