1. health and fitness
2. disease

Plateletworks POC Platelet Function
Results in 2 minutes with a standard cell counter!
• Platelet Count • Platelet Inhibition
• Platelet Aggregation • CBC
Cascade POC System
®
Point of Care for Whole Blood
Coagulation
The Cascade POC analyzer and
unique reagent system are useful in
monitoring routine anticoagulants and the
antithrombotic drugs used to treat angina,
MI, stroke, deep venous thrombosis and
pulmonary and arterial emboli. A built-in
battery pack and QC lockout features make
it ideal for use in the ER, cath lab, cardiac
surgery, warfarin clinics and physician
offices. Cascade POC offers a rapid POC
assay for monitoring the anticoagulant
effects of warfarin.
Testing is fast and easy:
1. Swipe test card through reader.
2. Insert card into analyzer and add sample.
3. View final results in minutes
Cascade POC Assays
• Efficient pre-surgical screen
• Monitor anti-platelet therapies
• Determine best use of transfusion resources
• Uses traditional ADP and collagen agonists
• No specialized training or equipment
• Use whole blood at the point of care
Actalyke POC Heparin
Assessment
Activated Clotting Time
• 2-point early clot detection
• Single and dual well models
• Extensive data handling
• Celite, Kaolin, Glass or MAX-ACT tests
• PT with INR (ISI ~ 1.0)
– PT-WB for fresh whole blood
– PT-C for citrated whole blood or plasma
800-231-5663 • www.helena.com
• aPTT for citrated whole blood or plasma
• c-ACT for fresh whole blood
Book M
8/11(4)
Helena Hemostasis
Helena Hemostasis
Prothrombin Time
Platelet Aggregation Studies
Helena Thromboplastins offer a range of ISI values
to provide a reagent that’s just right for your lab.
Reagents are prepared from rabbit brain tissue and
are suitable for automated, semi-automated and
manual applications.
Platelet aggregation is performed to identify abnormal
platelet function, to quantitate platelet response, and
to monitor platelet inhibition by drug therapy. Helena’s
platelet reagents provide outstanding stability and
reasonable pricing. Reagents are optimized for use with
Helena’s AggRAM, but may be used on any turbidometric
aggregometer of similar quality.
Thromboplastin-LI
• Ready for use; no mixing required
• Stability of open reagent: 14 days at 2-8°C
• Target ISI value: < 1.5
Thromboplastin-MI
• Convenient add-a-vial diluent included in kit to
eliminate pipetting errors and water problems
• Reconstituted stability: 7 days at 2-6°C
• Target ISI value: 1.6 to 1.8
Thromboplastin
• Reconstituted stability: 7 days at 2-6°C
• Target ISI value: 2.0 to 2.5
5248Thromboplastin-LI, 250 tests, 10 x 5 mL
5249Thromboplastin-LI, 500 tests, 10 x 10 mL
5274 Thromboplastin-MI with Diluent, 125 tests, 5 x 5 mL
5271 Thromboplastin-MI with Diluent, 250 tests, 5 x 10 mL
5272 Thromboplastin-MI with Diluent, 500 tests, 10 x 10 mL
5380 Thromboplastin, 200 tests, 10 x 4 mL 5381 Thromboplastin, 500 tests, 10 x 10 mL
5364
5366
5367
5368
5369
5199
5365
Arachidonic Acid, 2 x 1 mL
ADP, 2 x 1 mL
Epinephrine, 2 x 1 mL
Collagen, 2 x 1 mL
Platelet Aggregation Kit (5366, 5367, 5368)
Ristocetin (for RIPA), 10 x 0.5 mL
Tris-Buffered Saline, 1 x 125 mL
ADP
• Lyophilized preparation of adenosine-5-diphosphate
• Reconstitutes to a 20 µM stock solution
•Stability of stock solution: 1 week at 2-8°C or
3 months at -20°C
Collagen
Activated Partial Thromboplastin Time
Epinephrine
• Lyophilized preparation of L-epinephrine bitartrate
• Reconstitutes to 300 µM
• Stability of stock solution: 1 week at 2-8°C
Helena aPTT reagents are ready-to-use liquids for
convenience, high quality for precision, and priced
for economy. Reagents are suitable for photo-optical,
mechanical and manual (tilt tube) methods.
• Lyophilized preparation of sodium arachidonate
•Useful in evaluating aspirin-induced platelet dysfunction
•It has been suggested that this test be performed
before other testing to screen for drugs effecting platelet
responsiveness
Ristocetin
• Derived from the actinomycete Nocardia lurida
•For use in ristocetin-induced platelet aggregation (RIPA)
assays
• Concentration post-reconstitution is 15 mg/mL
• Reconstituted stability: 4 hours at 15-30°C or 1 month at -20°C
Ristocetin Cofactor Assay
aPTT-SA (Soluble Activator)
The Ristocetin Cofactor assay measures the ability of vWF in the patient’s plasma to agglutinate formalin-fixed
(metabolically inactive) platelets in the presence of ristocetin. This assay is more sensitive than RIPA to mild
reductions in vWF and more often used to monitor therapy in vWD patients.
• Soluble ellagic acid activator
• Optical clarity, homogeneous suspension a plus for automated systems
• Shorter activation time (~3 minutes vs. 5 minutes)
Ristocetin Cofactor Assay
5388
5389
5387
5386
Page 1
• One of the world’s best collagen preparations
• Clear stabilized liquid prepared from equine tendon
•10 µg/mL concentration
Arachidonic Acid
aPTT-SA & CaCl2, 250 tests, 5 x 5 mL
aPTT-SA & CaCl2, 500 tests, 5 x 10 mL
aPTT-SA, 1000 tests, 10 x 10 mL
0.025 M CaCl2, 10 x 10 mL
• Kit includes ristocetin (10 mg/mL; 2 x 1.5 mL), formalinized platelets (~200,000/mL; 4 x 5 mL), S.A.R.P. reference plasma (2 x 1 mL), abnormal control (R:Co <50%; 2 x 0.5 mL), and tris-buffered saline
(1 x 35 mL)
• Items also available separately
• Platelets in Cat. No. 5356 show a slower reaction rate
than platelets in Cat. No. 5371
5370
5356
5371
5373
5372
5365
Ristocetin Cofactor Kit, 60 tests
Lyophilized Platelets, 5 x 10 mL
Lyophilized Platelets, 5 x 5 mL
Ristocetin Cofactor Abnormal Control, 5 x 0.5 mL
Ristocetin (10 mg/mL), 5 x 1.5 mL
Tris-Buffered Saline, 1 x 125 mL
Page 6
Helena Hemostasis
Helena Hemostasis
Fibrinogen
vWF:Ag, PC & PS ELISA Assays
For quantitative assessment of fibrinogen, Helena’s Fibrinogen Assay is well-suited to automated, semiautomated and manual systems. Fibrinogen Assay components are available as a kit and separately.
ELISA kits offer sensitive and specific assays with
faster turnaround times, greater ease of use, and clearcut standardized results using established reference
preparations. Antigen assays employ 6-point reference
curves with accurate detection as low as 5% of normal.
Fibrinogen
•Clauss methodology for quantitation of fibrinogen in acquired and congenital disorders
•Uses high thrombin (~100 NIH units/mL) and low fibrinogen (2 to 50 mg/dL) concentrations so that
clotting times are dependent on plasma fibrinogen
•Not significantly effected by heparin concentrations below 0.6 USP units/mL and FDP below 100 µg/mL
von Willebrand Factor Antigen (vWF:Ag)
•Total incubation time 40 minutes at room temperature; overall
assay time 55 minutes for 96 determinations
•Linearity expressed as the coefficient of determination (r2)
0.995; mean accuracy 103.6%
Protein S (Free and Total)
5290 vWF:Ag ELISA Kit, 96 determinations
5291 Protein C ELISA Kit, 96 determinations
5292 Protein S ELISA Kit, 96 determinations
5374 Thrombin Reagent, 200 tests, 10 x 2 mL
5375 Owren’s Veronal Buffer, 10 x 25 mL
5379 Fibrinogen Calibrator, 10 x 1 mL
The Thrombin Clotting Time, or Thrombin Time (TT), assay
is ideal for qualitative assessment of plasma fibrinogen and
interfering substances such as FDP and heparin.
•Excellent, rapid screening test for qualitative
assessment of plasma fibrinogen and interfering
substances such as heparin and FDP
•Uses a low concentration of heparin (~3 NIH units/mL)
with undiluted plasma
• Sensitive to fibrinogen levels below 70 mg/dL
AggRAM™
5377 Thrombin Time Reagent, 250 tests, 10 x 5 mL
Cascade® M and Cascade® M-4
AggRAM, for platelet aggregation and
ristocetin cofactor testing, couples a
four-channel analyzer with the power of
Window®-based software for unsurpassed
testing flexibility. Up to two AggRAM
modules can be run on one Remote
Analyzer Module computer so you can
configure your analyzers to suit you
testing needs.
Cascade M and Cascade M-4 are manual hemostasis
analyzers that are ideal for all routine clotting assays - PTs,
aPTTs, thrombins, fibrinogens and factor assays. Operation is
simple and economical, with only a 15” x 15” footprint.
•Easy-to-use keyboard
•On-screen prompts
• State-of-the-art optics
• On-board quality control
registered trademark of Microsoft Corp.
Cat. No. 1484
Page 5
Thrombin Reagent 5 x 2 mL,
Fibrinogen Calibrator 2 x 1 mL,
Owren’s Veronal Buffer 2 x 25 mL
Thrombin Clotting Time
•Simultaneous measurement of Free and Total by pretreating
with PEG
•Linearity (r2) 0.985 for Total, 0.992 for Free; mean accuracy
101% for Total, 98% for Free
®Windows
Thrombin Clotting Time
Protein C
•Simple protocol - total incubation time 60 minutes; overall
assay time 75 minutes for 96 determinations
• Linearity (r2) 0.992; mean accuracy 99.4%
5376 Fibrinogen Assay Kit, 100 tests
Cat. No. 1711
Cat. No. 1710
Page 2
Helena Hemostasis
Helena Hemostasis
Hemostasis Controls and Reference Plasmas
Factor Deficient Substrates
Our controls and reference plasmas offer a sensible
means to monitor accuracy and precision in hemostasis
testing. We encourage you to enroll in our free Quality
Assurance Review (QAR) service.
Quality laboratory testing is essential to diagnosis
and treatment. Helena offers quality factor deficient
substrates with < 1% residual factor activity. All
substrates (except Factor II) are prepared from
human congenitally deficient donors.
PT, aPTT and Fibrinogen Controls
Congenital Factor Deficient Substrates
•Norm-Trol 1 is prepared from lyophilized normal human
plasma to provide a normal level control for PT, aPTT,
and Fibrinogen assays
5191
5192
5193
5194
5195
5196
5197
•Ab-Trol 2 and Ab-Trol 3 are lyophilized absorbed human
plasmas which provide moderately elevated and very
elevated, respectively, PT and aPTT controls
• Reconstituted controls: stable 8 hours at 2 to 6°C
Specialty Assayed Controls and Reference
Plasma
•S.A.R.P. is a highly acclaimed reference plasma
standardized to WHO and ISTH. It is prepared from a
frozen pool of citrated plasma from healthy donors. The
pool is buffered and lyophilized to ensure stability of all
plasma constituents.
•Our Specialty Assayed Controls are available in two
levels: S.A.C.-1 normal and S.A.C.-2 abnormal (<60%
of normal)
•S.A.R.P. and S.A.C. are assayed for these parameters:
PT, aPTT, Fibrinogen, Factors II, V, VII, VIII, IX, X,
XI, XII, Protein C, Protein S (free & total), Ristocetin
Cofactor, and vWF:Ag
Quality Assurance Review (QAR)
•We offer QAR, a free computer service for analyzing
daily QC data for shifts or trends and establishing mean
control values for individual laboratories
•QAR allows you to compare your results to other labs
using the same reagents, instruments and controls
•Retrospective peer reports include precision data on
the various instrument-reagent systems being used
•Ask to enroll in this free service when placing your
order for Norm-Trol 1, Ab-Trol 2, and Ab-Trol 3
5186
5187
5183
5301
5302
5185
Norm-Trol 1, 10 x 1 mL
Ab-Trol 2, 10 x 1 mL
Ab-Trol 3, 10 x 1 mL
S.A.C.-1 (Normal), 10 x 1 mL
S.A.C.-2 (Abnormal), 10 x 1 mL
S.A.R.P., 10 x 1 mL
Factor V Deficient Substrate, 10 x 1 mL
Factor VII Deficient Substrate, 10 x 1 mL
Factor VIII Deficient Substrate, 10 x 1 mL
Factor IX Deficient Substrate, 10 x 1 mL
Factor X Deficient Substrate, 10 x 1 mL
Factor XI Deficient Substrate, 10 x 1 mL
Factor XII Deficient Substrate, 10 x 1 mL
Bovine Factor Deficient Substrate Plasma
5190 Factor II Deficient Substrate, 10 x 1 mL
Laurell Rocket Electroimmunodiffusion (EID)
Complete line of supplies for quantitating vWF:Ag,
Protein C, and Protein S (Free and Total) by the
Laurell Rocket method, a technique which combines
the specificity of immunochemistry with the ease of
electrophoresis.
von Willebrand Factor Antigen
(vWF:Ag), Protein C and Protein S
• Crisp, easy-to-read, well-defined precipitin rockets
•All Helena rocket assays use same equipment
and technique for ease and convenience
•Components available separately for greater
economy
• Easy, accurate, specific antigen measurement
•Free Protein S can be assayed on the same plate
as total Protein S by treating the sample with Free
Protein S reagent
Page 3
5361
5016
5357
5359
5363
5358
5362
vWF:Ag Rocket Plates, 5 x 10 wells/plate
Electra B1 Buffer (for vWF:Ag), 10 x 14.1 g
Protein C Rocket Plates, 5 x 12 wells/plate
Protein S Rocket Plates, 5 x 12 wells/plate
Free Protein S Reagent, 5 x 2 mL
Tris-Tricine Buffer (for Proteins C & S),
10 x 14.1 g
Rocket Stain, 1 x 0.9 g
Page 4
Helena Hemostasis
Helena Hemostasis
Hemostasis Controls and Reference Plasmas
Factor Deficient Substrates
Our controls and reference plasmas offer a sensible
means to monitor accuracy and precision in hemostasis
testing. We encourage you to enroll in our free Quality
Assurance Review (QAR) service.
Quality laboratory testing is essential to diagnosis
and treatment. Helena offers quality factor deficient
substrates with < 1% residual factor activity. All
substrates (except Factor II) are prepared from
human congenitally deficient donors.
PT, aPTT and Fibrinogen Controls
Congenital Factor Deficient Substrates
•Norm-Trol 1 is prepared from lyophilized normal human
plasma to provide a normal level control for PT, aPTT,
and Fibrinogen assays
5191
5192
5193
5194
5195
5196
5197
•Ab-Trol 2 and Ab-Trol 3 are lyophilized absorbed human
plasmas which provide moderately elevated and very
elevated, respectively, PT and aPTT controls
• Reconstituted controls: stable 8 hours at 2 to 6°C
Specialty Assayed Controls and Reference
Plasma
•S.A.R.P. is a highly acclaimed reference plasma
standardized to WHO and ISTH. It is prepared from a
frozen pool of citrated plasma from healthy donors. The
pool is buffered and lyophilized to ensure stability of all
plasma constituents.
•Our Specialty Assayed Controls are available in two
levels: S.A.C.-1 normal and S.A.C.-2 abnormal (<60%
of normal)
•S.A.R.P. and S.A.C. are assayed for these parameters:
PT, aPTT, Fibrinogen, Factors II, V, VII, VIII, IX, X,
XI, XII, Protein C, Protein S (free & total), Ristocetin
Cofactor, and vWF:Ag
Quality Assurance Review (QAR)
•We offer QAR, a free computer service for analyzing
daily QC data for shifts or trends and establishing mean
control values for individual laboratories
•QAR allows you to compare your results to other labs
using the same reagents, instruments and controls
•Retrospective peer reports include precision data on
the various instrument-reagent systems being used
•Ask to enroll in this free service when placing your
order for Norm-Trol 1, Ab-Trol 2, and Ab-Trol 3
5186
5187
5183
5301
5302
5185
Norm-Trol 1, 10 x 1 mL
Ab-Trol 2, 10 x 1 mL
Ab-Trol 3, 10 x 1 mL
S.A.C.-1 (Normal), 10 x 1 mL
S.A.C.-2 (Abnormal), 10 x 1 mL
S.A.R.P., 10 x 1 mL
Factor V Deficient Substrate, 10 x 1 mL
Factor VII Deficient Substrate, 10 x 1 mL
Factor VIII Deficient Substrate, 10 x 1 mL
Factor IX Deficient Substrate, 10 x 1 mL
Factor X Deficient Substrate, 10 x 1 mL
Factor XI Deficient Substrate, 10 x 1 mL
Factor XII Deficient Substrate, 10 x 1 mL
Bovine Factor Deficient Substrate Plasma
5190 Factor II Deficient Substrate, 10 x 1 mL
Laurell Rocket Electroimmunodiffusion (EID)
Complete line of supplies for quantitating vWF:Ag,
Protein C, and Protein S (Free and Total) by the
Laurell Rocket method, a technique which combines
the specificity of immunochemistry with the ease of
electrophoresis.
von Willebrand Factor Antigen
(vWF:Ag), Protein C and Protein S
• Crisp, easy-to-read, well-defined precipitin rockets
•All Helena rocket assays use same equipment
and technique for ease and convenience
•Components available separately for greater
economy
• Easy, accurate, specific antigen measurement
•Free Protein S can be assayed on the same plate
as total Protein S by treating the sample with Free
Protein S reagent
Page 3
5361
5016
5357
5359
5363
5358
5362
vWF:Ag Rocket Plates, 5 x 10 wells/plate
Electra B1 Buffer (for vWF:Ag), 10 x 14.1 g
Protein C Rocket Plates, 5 x 12 wells/plate
Protein S Rocket Plates, 5 x 12 wells/plate
Free Protein S Reagent, 5 x 2 mL
Tris-Tricine Buffer (for Proteins C & S),
10 x 14.1 g
Rocket Stain, 1 x 0.9 g
Page 4
Helena Hemostasis
Helena Hemostasis
Fibrinogen
vWF:Ag, PC & PS ELISA Assays
For quantitative assessment of fibrinogen, Helena’s Fibrinogen Assay is well-suited to automated, semiautomated and manual systems. Fibrinogen Assay components are available as a kit and separately.
ELISA kits offer sensitive and specific assays with
faster turnaround times, greater ease of use, and clearcut standardized results using established reference
preparations. Antigen assays employ 6-point reference
curves with accurate detection as low as 5% of normal.
Fibrinogen
•Clauss methodology for quantitation of fibrinogen in acquired and congenital disorders
•Uses high thrombin (~100 NIH units/mL) and low fibrinogen (2 to 50 mg/dL) concentrations so that
clotting times are dependent on plasma fibrinogen
•Not significantly effected by heparin concentrations below 0.6 USP units/mL and FDP below 100 µg/mL
von Willebrand Factor Antigen (vWF:Ag)
•Total incubation time 40 minutes at room temperature; overall
assay time 55 minutes for 96 determinations
•Linearity expressed as the coefficient of determination (r2)
0.995; mean accuracy 103.6%
Protein S (Free and Total)
5290 vWF:Ag ELISA Kit, 96 determinations
5291 Protein C ELISA Kit, 96 determinations
5292 Protein S ELISA Kit, 96 determinations
5374 Thrombin Reagent, 200 tests, 10 x 2 mL
5375 Owren’s Veronal Buffer, 10 x 25 mL
5379 Fibrinogen Calibrator, 10 x 1 mL
The Thrombin Clotting Time, or Thrombin Time (TT), assay
is ideal for qualitative assessment of plasma fibrinogen and
interfering substances such as FDP and heparin.
•Excellent, rapid screening test for qualitative
assessment of plasma fibrinogen and interfering
substances such as heparin and FDP
•Uses a low concentration of heparin (~3 NIH units/mL)
with undiluted plasma
• Sensitive to fibrinogen levels below 70 mg/dL
AggRAM™
5377 Thrombin Time Reagent, 250 tests, 10 x 5 mL
Cascade® M and Cascade® M-4
AggRAM, for platelet aggregation and
ristocetin cofactor testing, couples a
four-channel analyzer with the power of
Window®-based software for unsurpassed
testing flexibility. Up to two AggRAM
modules can be run on one Remote
Analyzer Module computer so you can
configure your analyzers to suit you
testing needs.
Cascade M and Cascade M-4 are manual hemostasis
analyzers that are ideal for all routine clotting assays - PTs,
aPTTs, thrombins, fibrinogens and factor assays. Operation is
simple and economical, with only a 15” x 15” footprint.
•Easy-to-use keyboard
•On-screen prompts
• State-of-the-art optics
• On-board quality control
registered trademark of Microsoft Corp.
Cat. No. 1484
Page 5
Thrombin Reagent 5 x 2 mL,
Fibrinogen Calibrator 2 x 1 mL,
Owren’s Veronal Buffer 2 x 25 mL
Thrombin Clotting Time
•Simultaneous measurement of Free and Total by pretreating
with PEG
•Linearity (r2) 0.985 for Total, 0.992 for Free; mean accuracy
101% for Total, 98% for Free
®Windows
Thrombin Clotting Time
Protein C
•Simple protocol - total incubation time 60 minutes; overall
assay time 75 minutes for 96 determinations
• Linearity (r2) 0.992; mean accuracy 99.4%
5376 Fibrinogen Assay Kit, 100 tests
Cat. No. 1711
Cat. No. 1710
Page 2
Helena Hemostasis
Helena Hemostasis
Prothrombin Time
Platelet Aggregation Studies
Helena Thromboplastins offer a range of ISI values
to provide a reagent that’s just right for your lab.
Reagents are prepared from rabbit brain tissue and
are suitable for automated, semi-automated and
manual applications.
Platelet aggregation is performed to identify abnormal
platelet function, to quantitate platelet response, and
to monitor platelet inhibition by drug therapy. Helena’s
platelet reagents provide outstanding stability and
reasonable pricing. Reagents are optimized for use with
Helena’s AggRAM, but may be used on any turbidometric
aggregometer of similar quality.
Thromboplastin-LI
• Ready for use; no mixing required
• Stability of open reagent: 14 days at 2-8°C
• Target ISI value: < 1.5
Thromboplastin-MI
• Convenient add-a-vial diluent included in kit to
eliminate pipetting errors and water problems
• Reconstituted stability: 7 days at 2-6°C
• Target ISI value: 1.6 to 1.8
Thromboplastin
• Reconstituted stability: 7 days at 2-6°C
• Target ISI value: 2.0 to 2.5
5248Thromboplastin-LI, 250 tests, 10 x 5 mL
5249Thromboplastin-LI, 500 tests, 10 x 10 mL
5274 Thromboplastin-MI with Diluent, 125 tests, 5 x 5 mL
5271 Thromboplastin-MI with Diluent, 250 tests, 5 x 10 mL
5272 Thromboplastin-MI with Diluent, 500 tests, 10 x 10 mL
5380 Thromboplastin, 200 tests, 10 x 4 mL 5381 Thromboplastin, 500 tests, 10 x 10 mL
5364
5366
5367
5368
5369
5199
5365
Arachidonic Acid, 2 x 1 mL
ADP, 2 x 1 mL
Epinephrine, 2 x 1 mL
Collagen, 2 x 1 mL
Platelet Aggregation Kit (5366, 5367, 5368)
Ristocetin (for RIPA), 10 x 0.5 mL
Tris-Buffered Saline, 1 x 125 mL
ADP
• Lyophilized preparation of adenosine-5-diphosphate
• Reconstitutes to a 20 µM stock solution
•Stability of stock solution: 1 week at 2-8°C or
3 months at -20°C
Collagen
Activated Partial Thromboplastin Time
Epinephrine
• Lyophilized preparation of L-epinephrine bitartrate
• Reconstitutes to 300 µM
• Stability of stock solution: 1 week at 2-8°C
Helena aPTT reagents are ready-to-use liquids for
convenience, high quality for precision, and priced
for economy. Reagents are suitable for photo-optical,
mechanical and manual (tilt tube) methods.
• Lyophilized preparation of sodium arachidonate
•Useful in evaluating aspirin-induced platelet dysfunction
•It has been suggested that this test be performed
before other testing to screen for drugs effecting platelet
responsiveness
Ristocetin
• Derived from the actinomycete Nocardia lurida
•For use in ristocetin-induced platelet aggregation (RIPA)
assays
• Concentration post-reconstitution is 15 mg/mL
• Reconstituted stability: 4 hours at 15-30°C or 1 month at -20°C
Ristocetin Cofactor Assay
aPTT-SA (Soluble Activator)
The Ristocetin Cofactor assay measures the ability of vWF in the patient’s plasma to agglutinate formalin-fixed
(metabolically inactive) platelets in the presence of ristocetin. This assay is more sensitive than RIPA to mild
reductions in vWF and more often used to monitor therapy in vWD patients.
• Soluble ellagic acid activator
• Optical clarity, homogeneous suspension a plus for automated systems
• Shorter activation time (~3 minutes vs. 5 minutes)
Ristocetin Cofactor Assay
5388
5389
5387
5386
Page 1
• One of the world’s best collagen preparations
• Clear stabilized liquid prepared from equine tendon
•10 µg/mL concentration
Arachidonic Acid
aPTT-SA & CaCl2, 250 tests, 5 x 5 mL
aPTT-SA & CaCl2, 500 tests, 5 x 10 mL
aPTT-SA, 1000 tests, 10 x 10 mL
0.025 M CaCl2, 10 x 10 mL
• Kit includes ristocetin (10 mg/mL; 2 x 1.5 mL), formalinized platelets (~200,000/mL; 4 x 5 mL), S.A.R.P. reference plasma (2 x 1 mL), abnormal control (R:Co <50%; 2 x 0.5 mL), and tris-buffered saline
(1 x 35 mL)
• Items also available separately
• Platelets in Cat. No. 5356 show a slower reaction rate
than platelets in Cat. No. 5371
5370
5356
5371
5373
5372
5365
Ristocetin Cofactor Kit, 60 tests
Lyophilized Platelets, 5 x 10 mL
Lyophilized Platelets, 5 x 5 mL
Ristocetin Cofactor Abnormal Control, 5 x 0.5 mL
Ristocetin (10 mg/mL), 5 x 1.5 mL
Tris-Buffered Saline, 1 x 125 mL
Page 6
Plateletworks POC Platelet Function
Results in 2 minutes with a standard cell counter!
• Platelet Count • Platelet Inhibition
• Platelet Aggregation • CBC
Cascade POC System
®
Point of Care for Whole Blood
Coagulation
The Cascade POC analyzer and
unique reagent system are useful in
monitoring routine anticoagulants and the
antithrombotic drugs used to treat angina,
MI, stroke, deep venous thrombosis and
pulmonary and arterial emboli. A built-in
battery pack and QC lockout features make
it ideal for use in the ER, cath lab, cardiac
surgery, warfarin clinics and physician
offices. Cascade POC offers a rapid POC
assay for monitoring the anticoagulant
effects of warfarin.
Testing is fast and easy:
1. Swipe test card through reader.
2. Insert card into analyzer and add sample.
3. View final results in minutes
Cascade POC Assays
• Efficient pre-surgical screen
• Monitor anti-platelet therapies
• Determine best use of transfusion resources
• Uses traditional ADP and collagen agonists
• No specialized training or equipment
• Use whole blood at the point of care
Actalyke POC Heparin
Assessment
Activated Clotting Time
• 2-point early clot detection
• Single and dual well models
• Extensive data handling
• Celite, Kaolin, Glass or MAX-ACT tests
• PT with INR (ISI ~ 1.0)
– PT-WB for fresh whole blood
– PT-C for citrated whole blood or plasma
800-231-5663 • www.helena.com
• aPTT for citrated whole blood or plasma
• c-ACT for fresh whole blood
Book M
8/11(4)