1 NEBRASKA MEDICAID PREFERRED DRUG LIST As of 01/08/2015 (See Legend below Table) Note: Only drugs that are part of the listed therapeutic categories are affected by the PREFERRED DRUG LIST. For the most current version, check the Pharmacy Magellan Medicaid Administration, Inc. website at https://nebraska.fhsc.com. Additions and changes since the previous version are listed in italics. Please note that some sections may continue onto the following page. THERAPEUTIC DRUG CLASS ACNE AGENTS, TOPICAL (Implementation 07/17/2014) PREFERRED DRUGS AZELEX (azelaic acid) BENZACLIN W/PUMP (clindamycin/benzoyl peroxide) benzoyl peroxide generic OTC benzoyl peroxide generic Rx clindamycin phosphate SOLUTION DIFFERIN LOTION, CREAM (adapalene) DUAC (clindamycin/benzoyl peroxide) erythromycin GEL, SOLUTION tretinoin CREAM NON-PREFERRED DRUGS ACANYA (clindamycin and benzoyl peroxide) ACZONE (dapsone) adapalene gel, cream (generic Differin) AKNE-MYCIN (erythromycin) ATRALIN (tretinoin) AVITA (tretinoin) BENZACLIN GEL (clindamycin/ benzoyl peroxide) benzoyl peroxide foam (generic for Benzefoam) benzoyl peroxide gel Rx CLINDAGEL (clindamycin) clindamycin GEL, LOTION, FOAM clindamycin/benzoyl peroxide (generic for Benzaclin) DIFFERIN GEL EPIDUO (adapalene/benzoyl peroxide) erythromycin-benzoyl peroxide (generic for Benzamycin and Duac) EVOCLIN (clindamycin) FABIOR (tazarotene foam) INOVA (benzoyl peroxide) KLARON (sulfacetamide) NEUAC (clindamycin/benzoyl peroxide)NR RETIN-A GEL, CREAM RETIN-A MICRO (tretinoin microspheres) sulfacetamide sulfacetamide/sulfur SUMADAN (sulfacetamide/sulfur) TAZORAC (tazarotene) tretinoin GEL tretinoin microspheres (generic for Retin-A Micro) VELTIN (clindamycin and tretinoin) ZIANA (clindamycin and tretinoin) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. THERAPEUTIC DRUG CLASS ALZHEIMER’S DRUGS (Implementation 12/04/2014) ANALGESICS, OPIATE LONG-ACTING (Implementation 07/17/2014) ANALGESICS, OPIATE SHORT-ACTING (Implementation 07/17/2014) 2 PREFERRED NON-PREFERRED DRUGS DRUGS CHOLINESTERASE INHIBITORS donepezil 23 (generic for Aricept 23) donepezil (generic for Aricept) galantamine (generic for Razadyne) donepezil ODT (generic for Aricept ODT) galantamine ER (generic for Razadyne EXELON Transdermal (rivastigmine) ER) rivastigmine (generic for Exelon) NMDA RECEPTOR ANTAGONIST NAMENDA (memantine) NAMENDA XR (memantine ER) fentanyl patches BUTRANS (buprenorphine, transdermal)* KADIAN (morphine ER capsule) CONZIP (tramadol extended release)* methadone DURAGESIC MATRIX (fentanyl) morphine ER tablet (generic for MS Contin, hydromorphone ER (generic for Exalgo)* Oramorph SR) morphine ER capsule (generic for Avinza) OXYCONTIN (oxycodone ER) morphine ER capsule (generic for Kadian) NUCYNTA ER (tapentadol)* oxycodone ER (generic for re-formulated Oxycontin) oxymorphone ER (generic for OPANA ER) tramadol extended release* (generic for ULTRAM ER) ZOHYDRO ER (hydrocodone bitartrate ER) ORAL codeine ORAL SOLUTION acetaminophen/codeine codeine ORAL dihydrocodeine/aspirin/caffeine hydrocodone/APAP (generic for Synalgos DC) hydrocodone/ibuprofen ENDODAN (oxycodone/aspirin) hydromorphone TABLETS HYCET (hydrocodone/acetaminophen) morphine ORAL hydromorphone ORAL LIQUID, SUPPOSITORIES (generic for oxycodone TABLET Dilaudid) oxycodone/APAP IBUDONE (hydrocodone/ibuprofen) ROXICET SOLUTION levorphanol (oxycodone/acetaminophen) tramadol meperidine (generic for Demerol) morphine SUPPOSITORIES NUCYNTA (tapentadol)* OXECTA (oxycodone) oxycodone CAPSULE oxycodone/aspirin oxycodone/ibuprofen (generic for Combunox) oxymorphone (generic for Opana) pentazocine/APAP pentazocine/naloxone PRIMLEV (oxycodone/acetaminophen) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. THERAPEUTIC DRUG CLASS ANDROGENIC DRUGS (Topical) (Implementation 07/17/2014) ANGIOTENSIN MODULATORS (Implementation 07/17/2014) PREFERRED DRUGS 3 NON-PREFERRED DRUGS ROXICODONE TABLET (oxycodone) tramadol/APAP –generic for Ultracet (note: separate ingredients preferred) VICOPROFEN (hydrocodone/ibuprofen) XARTEMIS XR NR (oxycodone/acetaminophen) XODOL (hydrocodone/acetaminophen) ZAMICET (hydrocodone/acetaminophen solution) NASAL butorphanol nasal spray BUCCAL/TRANSMUCOSAL ABSTRAL (fentanyl transmucosal)* fentanyl transmucosal* (generic for Actiq) FENTORA (fentanyl)* SUBSYS (fentanyl spray)* ANDROGEL (testosterone) ANDRODERM (testosterone) TESTIM (testosterone) AXIRON (testosterone) FORTESTA (testosterone) testosterone (generic for Fortesta) testosterone (generics for Testim and Vogelxo) VOGELXO (testosterone) ACE INHIBITORS benazepril (generic for Lotensin) EPANED (enalapril) oral solution captopril (generic for Capoten) moexepril (generic for Univasc) enalapril (generic for Vasotec) perindopril (generic for Aceon) fosinopril (generic for Monopril) trandolapril (generic for Mavik) lisinopril (generic for Prinivil/Zestril) quinapril (generic for Accupril) ramipril (generic for Altace) ACE INHIBITOR/DIURETIC COMBINATIONS benazepril/HCTZ (generic for Lotensin HCT) fosinopril/HCTZ (generic for Monopril HCT) captopril/HCTZ (generic for Capozide) moexepril/HCTZ (generic for Uniretic) enalapril/HCTZ (generic for Vaseretic) quinapril/HCTZ (generic for Accuretic) lisinopril/HCTZ (generic Prinzide/Zestoretic) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. THERAPEUTIC DRUG CLASS Individual prescriptions for the components of these products should be used for patients requiring these drug combinations. ANTIBIOTICS, GASTROINTESTINAL (Implementation 07/17/2014) Note: Although azithromycin, ciprofloxacin, and trimethoprim/sulfamethoxazole are not included in this review, they are available without prior authorization. 4 PREFERRED NON-PREFERRED DRUGS DRUGS ANGIOTENSIN RECEPTOR BLOCKERS DIOVAN (valsartan) BENICAR (olmesartan) irbesartan (generic for Avapro) candesartan (generic for Atacand) losartan (generic for Cozaar) EDARBI (azilsartan medoxomil) EDARBYCLOR (azilsartan/chlorthalidone) eprosartan (generic for Teveten) telmisartan (generic for Micardis) valsartan (generic for Diovan) ANGIOTENSIN RECEPTOR BLOCKER/DIURETIC COMBINATIONS DIOVAN-HCT (valsartan/HCTZ) BENICAR-HCT (olmesartan/HCTZ) irbesartan/HCTZ (generic for Avalide) candesartan/HCTZ (generic for AtacandHCT) losartan/HCTZ (generic for Hyzaar) telmisartan/HCTZ (generic for Micardis-HCT) TEVETEN-HCT (eprosartan/HCTZ) valsartan-HCTZ (generic for Diovan-HCT) ANGIOTENSIN MODULATOR / CALCIUM CHANNEL BLOCKER COMBINATIONS benazepril/amlodipine (generic for Lotrel) AMTURNIDE (aliskiren/amlodipine/HCTZ) TARKA (trandolapril/verapamil) AZOR (olmesartan/amlodipine) EXFORGE (valsartan/amlodipine) TEKAMLO (aliskiren/amlodipine) telmisartan/amlodipine (generic for Twynsta) TRIBENZOR (amlodipine/olmesartan/HCTZ) valsartan/amlodipine (generic for Exforge) valsartan/amlodipine/HCTZ (generic for Exforge HCT) DIRECT RENIN INHIBITORS TEKTURNA (aliskiren) DIRECT RENIN INHIBITOR COMBINATIONS AMTURNIDE (aliskiren/amlodipine/HCTZ) TEKAMLO (aliskiren/amlodipine) TEKTURNA/HCT (aliskiren/HCTZ) metronidazole TABLETS ALINIA (nitazoxanide) neomycin DIFICID (fidaxomicin) FLAGYL ER (metronidazole) vancomycin compounded oral solution metronidazole CAPSULES tinidazole (generic for Tindamax) vancomycin capsules (generic for Vancocin) XIFAXAN (rifaximin) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 5 THERAPEUTIC DRUG CLASS ANTIBIOTICS, INHALED (Implementation 07/17/2014) ANTIBIOTICS, TOPICAL (Implementation 07/17/2014) ANTIBIOTICS, VAGINAL (Implementation 07/17/2014) ANTICOAGULANTS (Implementation 07/17/2014) ANTIEMETICS /ANTIVERTIGO AGENTS (Implementation 07/17/2014) PREFERRED DRUGS BETHKIS (tobramycin) TOBI (tobramycin) TOBI-PODHALER (tobramycin)* bacitracin ointment bacitracin/polymyxin (generic for Polysporin) mupirocin OINTMENT (generic for Bactroban) neomycin/polymyxin/bacitracin (generic for Neosporin, Triple AB) CLEOCIN OVULES (clindamycin, vaginal suppositories) clindamycin (vaginal) (generic for Cleocin) METROGEL (metronidazole, vaginal) NON-PREFERRED DRUGS CAYSTON (aztreonam lysine)QL, * tobramycin (generic for TOBI) ELIQUIS (apixaban) enoxaparin (generic for Lovenox) FRAGMIN (dalteparin) PRADAXA (dabigatran) warfarin (generic for Coumadin) XARELTO (rivaroxaban) fondaparinux (generic for Arixtra) LOVENOX (enoxaparin) XARELTO STARTER PACK (rivaroxaban) ALTABAX (retapamulin) CENTANY (mupirocin ointment) gentamicin OINTMENT, CREAM mupirocin CREAM (generic for Bactroban) CLINDESSE (clindamycin, vaginal) metronidazole (vaginal) VANDAZOLE (metronidazole, vaginal) CANNABINOIDS CESAMET (nabilone) dronabinol (generic for Marinol) 5HT3 RECEPTOR BLOCKERS ondansetron (generic for Zofran) ANZEMET (dolasetron) ondansetron ODT (generic for Zofran) granisetron (generic for Kytril) SANCUSO (granisetron) ZUPLENZ (ondansetron) NK-1 RECEPTOR ANTAGONIST AKYNZEO (netupitant/palonosetron)NR EMEND (aprepitant)QL, * TRADITIONAL ANTIEMETICS DICLEGIS (doxylamine/pyridoxine)** COMPRO (prochlorperazine rectal) **females only METOZOLV ODT (metoclopramide) dimenhydrinate (generic for Dramamine) prochlorperazine rectal (generic for Compazine) hydroxyzine (generic for Vistaril) promethazine suppositories 50mg meclizine (generic for Antivert) trimethobenzamide oral (generic for Tigan) metoclopramide (generic for Reglan) Marinol (dronabinol) phosphoric acid/dextrose/fructose solution (generic for Emetrol) prochlorperazine oral (generic for Compazine) promethazine oral (generic for Phenergan) promethazine suppositories 12.5mg, 25mg TRANSDERM-SCOP (scopolamine) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. THERAPEUTIC DRUG CLASS ANTIFUNGALS, ORAL (Implementation 07/17/2014) ANTIFUNGALS, TOPICAL (Implementation 07/17/2014) 6 NON-PREFERRED DRUGS flucytosine (generic for Ancobon)* GRIFULVIN V (griseofulvin) griseofulvin tablets griseofulvin ultramicrosize itraconazole (generic for Sporanox) ketoconazole (generic for Nizoral) LAMISIL GRANULES (terbinafine) NOXAFIL (posaconazole)* NOXAFIL DR (posaconazole DR)* nystatin POWDER for reconstitution ONMEL (itraconazole) ORAVIG (miconazole buccal) SPORANOX (itraconazole)* voriconazole (generic for VFEND)* ANTIFUNGAL ALEVAZOL (clotrimazole)NR clotrimazole (generic for Lotrimin) RX, OTC econazole (generic for Spectazole) BENSAL HP (salicylic acid) ketoconazole cream (generic for Nizoral) ciclopirox cream/gel/suspension (generic for Ciclodan, Loprox) ketoconazole shampoo (generic for Nizoral) ciclopirox nail lacquer (solution) (generic LAMISIL AT CREAM (terbinafine) OTC for Penlac) LAMISIL AT GEL (terbinafine) OTC ciclopirox shampoo (generic for Loprox) LAMISIL SPRAY OTC (terbinafine) DESENEX AERO POWDER OTC miconazole OTC CREAM, SPRAY, (miconazole) POWDER ERTACZO (sertaconazole) NUZOLE (miconazole) EXELDERM (sulconazole) nystatin EXTINA (ketoconazole) selenium sulfide 2.5% FUNGOID OTC terbinafine OTC (generic for Lamisil AT) NR TINACTIN AERO POWDER (tolnaftate) OTC JUBLIA (efinaconazole) ketoconazole FOAM (generic for Ketodan) TINACTIN CREAM (tolnaftate) OTC LOTRIMIN AF CREAM OTC tolnaftate OTC (generic for Tinactin) (clotrimazole) LUZU (luliconazole) MENTAX (butenafine) miconazole OTC OINTMENT NAFTIN (naftifine) OXISTAT (oxiconazole) selenium sulfide 2.25% VUSION (miconazole/ zinc oxide) ANTIFUNGAL/STEROID COMBINATIONS clotrimazole/betamethasone CREAM clotrimazole/betamethasone LOTION (generic for Lotrisone) (generic for Lotrisone) nystatin/triamcinolone (gen. for Mycolog) PREFERRED DRUGS clotrimazole (mucous membrane, troche) fluconazole (generic for Diflucan) griseofulvin suspension GRIS-PEG (griseofulvin) nystatin TABLET, SUSPENSION terbinafine (generic for Lamisil) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. THERAPEUTIC DRUG CLASS ANTIHISTAMINES, MINIMALLY SEDATING (Implementation 01/08/2015) PREFERRED DRUGS cetirizine (generic for Zyrtec) (swallow tablets and solution) loratadine (generic for Claritin) (swallow tablets and solution) ANTIHYPERTENSIVES, SYMPATHOLYTICS (Implementation 01/08/2015) CATAPRES-TTS (clonidine transdermal) clonidine ORAL (generic for Catapres) guanfacine (generic for Tenex) methyldopa allopurinol (generic for Zyloprim) probenecid probenecid/colchicine (generic for ColProbenecid) ANTIHYPERURICEMICS (Implementation 01/08/2015) ANTIMIGRAINE DRUGSQL, TRIPTANS Note: There are Quantity Limits for entire class. 7 NON-PREFERRED DRUGS cetirizine chewable (generic for Zyrtec) desloratadine (generic for Clarinex) desloratadine ODT (generic for Clarinex Reditabs) fexofenadine (generic for Allegra) levocetirizine (generic for Xyzal) loratadine dispersible (generic for Claritin Reditabs) clonidine transdermal CLORPRES (chlorthalidone/clonidine) methyldopa/hydrochlorothiazide reserpine COLCRYS (colchicine)* ULORIC (febuxostat)* ORAL AXERT (almotriptan) FROVA (frovatriptan) IMITREX oral (sumatriptan) naratriptan (generic for Amerge) rizatriptan (generic for Maxalt/Maxalt MLT) TREXIMET (sumatriptan/naproxen) zolmitriptan (generic for Zomig/ Zomig ZMT) RELPAX (eletriptan) sumatriptan generic oral (Implementation 07/17/2014) NASAL IMITREX (sumatriptan) sumatriptan generic nasal ZOMIG (zolmitriptan) INJECTABLE IMITREX (sumatriptan) PEN, CARTRIDGE sumatriptan generic VIAL ANTIPARASITICS, TOPICAL (Implementation 07/17/2014) permethrin 1% OTC (generic for Nix) permethrin 5% RX (generic for Elimite) pyrethrin/piperonyl butoxide (generic for RID, A-200) ALSUMA (sumatriptan) IMITREX (sumatriptan) VIAL sumatriptan SYRINGE, KIT SUMAVEL DOSEPRO (sumatriptan) EURAX (crotamiton) CREAM EURAX (crotamiton) LOTION lindane malathion (generic for Ovide) SKLICE (ivermectin) spinosad (generic for Natroba) ULESFIA (benzyl alcohol) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 8 THERAPEUTIC DRUG CLASS ANTIPARKINSON’S DRUGS(Oral) (Implementation 01/08/2015) PREFERRED DRUGS NON-PREFERRED DRUGS ANTICHOLINERGICS benztropine (generic for Cogentin) trihexyphenidyl (generic for Artane) COMT INHIBITORS entacapone (generic for Comtan) TASMAR (tolcapone) DOPAMINE AGONISTS bromocriptine (generic for Parlodel) MIRAPEX ER (pramipexole)* pramipexole (generic for Mirapex) NEUPRO (rotigotine)* ropinirole (generic for Requip) ropinirole extended release (generic for REQUIP XL)* MAO-B INHIBITORS selegiline tablets (generic for Eldepryl) AZILECT (rasagiline) selegiline capsules (gen. for Eldepryl) ZELAPAR (selegiline) ANTIPSORIATICS, ORAL (Implementation 01/08/2015) ANTIPSORIATICS, TOPICAL (Implementation 01/08/2015) ANTIVIRALS, ORAL (Implementation 07/17/2014) OTHER ANTIPARKINSON’S DRUGS carbidopa/levodopa (generic for Sinemet) carbidopa/levodopa ODT (generic for carbidopa/levodopa ER Parcopa) (generic for Sinemet CR) levodopa/carbidopa/entacapone (generic for Stalevo) STALEVO (levodopa/carbidopa/entacapone) acitretin (generic for Soriatane) SORIATANE (acitretin) methoxsalen (generic for Oxsoralen-Ultra) OXSORALEN-ULTRA (methoxsalen) 8-MOP (methoxsalen) calcipotriene CREAM calcipotriene OINTMENT calcipotriene solution calcitriol (generic for Vectical) calcipotriene/betamethasone (generic for Taclonex ointment) CALCITRENE (calcipotriene ointment) DOVONEX CREAM (calcipotriene) SORILUX (calcipotriene foam) TACLONEX SCALP (calcipotriene/ betamethasone) ANTI-HERPETIC DRUGS acyclovir (generic for Zovirax) famciclovir (generic for Famvir) valacyclovir (generic for Valtrex) SITAVIG (acyclovir buccal) NR ANTI-INFLUENZA DRUGS amantadine CAPSULE, SYRUP amantadine TABLET (generic for Symmetrel) RELENZA (zanamivir) inhalationQL rimantadine (generic for Flumadine) TAMIFLU (oseltamivir) QL BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 9 THERAPEUTIC DRUG CLASS ANTIVIRALS, TOPICAL (Implementation 07/17/2014) ANXIOLYTICS (Implementation 01/08/2015) BENIGN PROSTATIC HYPERPLASIA (BPH) TREATMENTS (Implementation 07/17/2014) BETA BLOCKERS (Oral) (Implementation 07/17/2014) PREFERRED DRUGS NON-PREFERRED DRUGS acyclovir OINTMENT (generic for Zovirax) DENAVIR (penciclovir) XERESE (acyclovir/hydrocortisone) ZOVIRAX Cream (acyclovir) alprazolam ER (generic for Xanax XR) alprazolam ODT alprazolam INTENSOL diazepam INTENSOL meprobamate oxazepam alprazolam tablet (generic for Xanax) buspirone chlordiazepoxide clorazepate (generic forTranxene-T) diazepam solution diazepam tablet lorazepam INTENSOL lorazepam tablet (generic for Ativan) ALPHA BLOCKERS alfuzosin (generic for Uroxatral) CARDURA XL (doxazosin) doxazosin (generic for Cardura) JALYN (dutasteride/tamsulosin) RAPAFLO (silodosin) tamsulosin (generic for Flomax) UROXATRAL (alfuzosin) terazosin (generic for Hytrin) 5-ALPHA-REDUCTASE (5AR) INHIBITORS finasteride (generic for Proscar) AVODART (dutasteride) JALYN (dutasteride/tamsulosin) BETA BLOCKERS acebutolol (generic for Sectral) betaxolol (generic for Kerlone) atenolol (generic for Tenormin) BYSTOLIC (nebivolol) atenolol/chlorthalidone(generic for Tenoretic) DUTOPROL bisoprolol (generic for Zebeta) (metoprolol XR and HCTZ) bisoprolol/HCTZ (generic for Ziac) HEMANGEOL (propranolol) oral solutionNR metoprolol (generic for Lopressor) INNOPRAN XL (propranolol) metoprolol XL (generic for Toprol XL) LEVATOL (penbutolol) propranolol (generic for Inderal) metoprolol/HCTZ (generic for propranolol extended release (Inderal LA) Lopressor HCT) TOPROL XL (metoprolol) nadolol (generic for Corgard) nadolol/bendroflumethiazide (generic for Corzide) pindolol (generic for Viskin) propranolol/hydrochlorothiazide (generic for Inderide) timolol (generic for Blocadren) BETA- AND ALPHA- BLOCKERS carvedilol (generic for Coreg) COREG CR (carvedilol) labetalol (generic for Trandate) ANTIARRHYTHMIC sotalol (generic for Betapace) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. THERAPEUTIC DRUG CLASS BILE SALTS (Implementation 01/08/2015) BLADDER RELAXANT PREPARATIONS (Implementation 07/17/2014) BONE RESORPTION SUPPRESSION AND RELATED DRUGS (Implementation 07/17/2014) BRONCHODILATORS, BETA AGONIST (Implementation 01/08/2015) 10 NON-PREFERRED DRUGS CHENODAL (chenodiol) ursodiol capsule 300mg (generic for Actigall) ENABLEX (darifenacin) GELNIQUE (oxybutynin) MYRBETRIQ (mirabegron) OXYTROL (oxybutynin) tolterodine (generic for Detrol) tolterodine ER (generic for Detrol LA) trospium (generic for Sanctura) trospium ER (generic for Sanctura XR) BISPHOSPHONATES alendronate (generic for Fosamax) ACTONEL (risedronate) (daily and weekly formulations) ATELVIA DR (risedronate) BINOSTO (alendronate effervescent) etidronate disodium (generic for Didronel) FOSAMAX Oral Solution (alendronate) FOSAMAX PLUS D ibandronate (generic for Boniva) risedronate (generic for Actonel) OTHER BONE RESORPTION SUPPRESSION AND RELATED DRUGS EVISTA (raloxifene) calcitonin-salmon nasal FORTICAL (calcitonin) nasal FORTEO (teriparatide) subcutaneousQL MIACALCIN (calcitonin) nasal raloxifene (generic for Evista) INHALERS-Short Acting PROVENTIL HFA (albuterol) PROAIR HFA (albuterol) VENTOLIN HFA (albuterol) XOPENEX HFA (levalbuterol) INHALERS – Long Acting FORADIL (formoterol) ARCAPTA NEOHALER (indacaterol) STRIVERDI RESPIMAT (olodaterol) SEREVENT (salmeterol) INHALATION SOLUTION albuterol (2.5mg/3ml premix or 2.5mg/0.5ml) albuterol low dose (0.63mg/3ml & 1.25mg/3ml) albuterol/ipratropium(generic for Duoneb) BROVANA (arformoterol) levalbuterol (generic for Xopenex) PERFOROMIST (formoterol) ORAL albuterol syrup albuterol tablets albuterol ER (generic for Vospire ER) metaproterenol (formerly generic for terbutaline (generic for Brethine) Alupent) PREFERRED DRUGS ursodiol 250mg tablet (generic for URSO) ursodiol 500mg tablet (generic for URSO FORTE) oxybutynin IR (generic for Ditropan) oxybutynin ER (generic for Ditropan XL) TOVIAZ (fesoterodine ER) VESICARE (solifenacin) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 11 THERAPEUTIC DRUG CLASS CALCIUM CHANNEL BLOCKERS (Oral) (Implementation 07/17/2014) CEPHALOSPORINS (Oral) and RELATED ANTIBIOTICS (Implementation 07/17/2014) PREFERRED DRUGS NON-PREFERRED DRUGS SHORT-ACTING Dihydropyridines nifedipine (generic for Procardia) isradipine (generic for Dynacirc) nicardipine (generic for Cardene) nimodipine (generic for Nimotop) NYMALIZE (nimodipine solution) Non-dihydropyridine diltiazem (generic for Cardizem) verapamil (generic for Calan, Isoptin) LONG-ACTING Dihydropyridines amlodipine (generic for Norvasc) CARDENE SR (nicardipine) nifedipine ER (generic for Procardia XL, felodipine ER (generic for Plendil) Adalat CC) nisoldipine (generic for Sular) Non-dihydropyridines diltiazem ER (generic for Cardizem CD) CALAN SR (verapamil) verapamil ER TABLET diltiazem LA (generic for Cardizem LA) verapamil ER PM (generic for Verelan PM) MATZIM LA (diltiazem) TIAZAC (diltiazem) verapamil ER CAPSULE verapamil 360mg capsule BETA LACTAM/BETA-LACTAMASE INHIBITOR COMBINATIONS amoxicillin/clavulanate TABLETS, CHEW amoxicillin/clavulanate XR TABLETS, SUSPENSION (generic for Augmentin XR) AUGMENTIN 125MG/5ML SUSPENSION AUGMENTIN 250MG/5ML SUSPENSION AUGMENTIN (amoxicillin/clavulanate) CEPHALOSPORINS – First Generation cefadroxil (oral) CAPSULE, SUSPENSION cefadroxil (oral) TABLET (generic for Duricef) (generic for Duricef) cephalexin CAPSULE, SUSPENSION cephalexin TABLET (generic for Keflex) CEPHALOSPORINS – Second Generation cefprozil (oral) (generic for Cefzil) cefaclor (oral) (generic for Ceclor) cefuroxime (oral tablet) (generic for Ceftin) CEFTIN (cefuroxime) tablets, suspension CEPHALOSPORINS – Third Generation cefdinir (oral) (generic for Omnicef) CEDAX (ceftibuten) SUPRAX SUSPENSION, CAPSULE cefpodoxime (oral) (generic for Vantin) (cefixime) SUPRAX CHEWABLE TABLET, TABLET (cefixime) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 12 THERAPEUTIC DRUG CLASS CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) AGENTS (Implementation 01/08/2015) COLONY STIMULATING FACTORS (Implementation 07/17/2014) PREFERRED DRUGS NON-PREFERRED DRUGS INHALERS ATROVENT HFA (ipratropium) ANORO ELLIPTA (umeclidinium/ COMBIVENT RESPIMAT (albuterol/ vilanterol) SPIRIVA RESPIMAT (tiotropium)NR ipratropium) SPIRIVA (tiotropium) TUDORZA PRESSAIR (aclidinium br) INHALATION SOLUTION albuterol/ipratropium (generic for Duoneb) ipratropium solution (generic for Atrovent) ORAL AGENT DALIRESP (roflumilast)* XANTHINES (not reviewed by the PDL process but are covered without prior authorization) theophylline NEUPOGEN (filgrastim) VIAL* NEUPOGEN (filgrastim) DISP SYR (Entire class requires prior authorization when administered outside physician office or hospital) CYTOKINE & CAM ANTAGONISTS (Implementation 01/08/2015) (Note: only self-administered, out-patient ENBREL (etanercept) HUMIRA (adalimumab) medications included in this review) EPINEPHRINE, SELFINJECTED (Implementation 01/08/2015) EPIPEN EPIPEN JR. ERYTHROPOIESIS STIMULATING PROTEINS (Implementation 07/17/2014) EPOGEN (rHuEPO)* PROCRIT (rHuEPO)* ACTEMRA subcutaneous (tocilizumab) CIMZIA (certolizumab pegol) KINERET (anakinra) ORENCIA (abatacept) Subcutaneous OTEZLA (apremilast oral) SIMPONI (golimumab) XELJANZ (tofacitinib oral) AUVI-Q epinephrine (generic for Adrenaclick) ADRENACLICK (Entire class requires prior authorization when administered outside physician office or hospital) FLUOROQUINOLONES, ORAL (Implementation 07/17/2014) ciprofloxacin (generic for Cipro) levofloxacin TABLETS (generic for Levaquin) ciprofloxacin ER ciprofloxacin suspension (generic for Cipro Suspension) levofloxacin oral solution moxifloxacin (generic for Avelox) NOROXIN (norfloxacin) ofloxacin BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 13 THERAPEUTIC DRUG CLASS GLUCOCORTICOIDS, INHALED (Implementation 01/08/2015) GROWTH HORMONE (Implementation 07/17/2014) Entire class requires prior authorization based on clinical criteria: https://nebraska.fhsc.com/Downl oads/NEfaxform_GH-201311.pdf H.PYLORI TREATMENTS (Implementation 07/17/2014) HEPATITIS C TREATMENTS (Implementation 07/17/2014) Entire class requires prior authorization based on clinical criteria: https://nebraska.fhsc.com/Downl oads/NEfaxform_HepatitisC201409.pdf HISTAMINE II RECEPTOR BLOCKERS (Implementation 01/08/2015) PREFERRED DRUGS NON-PREFERRED DRUGS GLUCOCORTICOIDS ASMANEX (mometasone) ALVESCO (ciclesonide) AEROSPAN (flunisolide) FLOVENT DISKUS (fluticasone) FLOVENT HFA (fluticasone) PULMICORT FLEXHALER (budesonide) QVAR (beclomethasone) GLUCOCORTICOID/BRONCHODILATOR COMBINATIONS ADVAIR HFA ADVAIR DISKUS (fluticasone/salmeterol) BREO ELLIPTA (fluticasone/vilanterol) DULERA (mometasone/formoterol) SYMBICORT (budesonide/ formoterol) INHALATION SOLUTION budesonide respules (generic for Pulmicort) PULMICORT RESPULES (budesonide) NORDITROPIN (somatropin) GENOTROPIN (somatropin) NUTROPIN (somatropin) HUMATROPE (somatropin) NUTROPIN AQ (somatropin) OMNITROPE (somatropin) SAIZEN (somatropin) SEROSTIM (somatropin) TEV-TROPIN (somatropin) ZORBTIVE (somatropin) OMECLAMOX-PAK (omeprazole, PYLERA (bismuth, metronidazole, clarithromycin, amoxicillin) tetracycline) lansoprazole/amoxicillin/clarithromycin PREVPAC (lansoprazole, amoxicillin, (generic for Prevpac) clarithromycin) INTERFERON PEGASYS INFERGEN (interferon alfacon-1) (pegylated interferon alfa-2a)* PEG-INTRON (pegylated interferon alfa-2b)* NUCLEOTIDE ANALOG POLYMERASE INHIBITOR HARVONI (sofosbuvir/ledipasvir)NR SOVALDI (sofosbuvir)* PROTEASE INHIBITOR INCIVEK (telaprevir)* OLYSIO (simeprevir)* VICTRELIS (boceprevir)* RIBAVIRIN ribavirin 200mg tablets/capsules REBETOL SOLUTION (ribavirin) famotidine tablet (generic for Pepcid) cimetidine solution ranitidine TABLET (generic for Zantac) cimetidine tablet (generic for Tagamet) ranitidine syrup famotidine SUSPENSION nizatidine (generic for Axid) ranitidine CAPSULE BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 14 THERAPEUTIC DRUG CLASS HYPOGLYCEMICS, ALPHA-GLUCOSIDASE INHIBITORS (Implementation 07/17/2014) PREFERRED DRUGS acarbose (generic for Precose) Glyset (miglitol) HYPOGLYCEMICS, INCRETIN MIMETICS/ENHANCERS (Implementation 07/17/2014) Glucagon-Like Peptide-1 BYDUREON (exenatide ER) subcutaneous** Receptor Agonist BYETTA (exenatide) subcutaneous** (GLP-1 RA) ** Requires metformin trial and diagnosis of https://nebraska.fhsc.com/Downl diabetes. oads/NEfaxform_GLP-1_RA201406.pdf Amylin Analog https://nebraska.fhsc.com/Downl oads/NEfaxform_Amylin201403.pdf Dipeptidyl peptidase-4 (DPP-4) JANUMET (sitagliptin/metformin)QL Inhibitor JANUMET XR(sitagliptin/metformin)QL JANUVIA (sitagliptin)QL JENTADUETO (linagliptin/metformin)QL TRADJENTA (linagliptin)QL HYPOGLYCEMICS, INSULIN AND RELATED DRUGS (Implementation 07/17/2014) HUMALOG (insulin lispro) HUMALOG MIX (insulin lispro/lispro protamine) HUMULIN (insulin) LANTUS (insulin glargine) LEVEMIR (insulin detemir) HYPOGLYCEMICS, MEGLITINIDES (Implementation 07/17/2014) NON-PREFERRED DRUGS BYDUREON PEN (exenatide ER) subcutaneous** TANZEUM (albiglutide)NR TRULICITY (dulaglutide)NR VICTOZA (liraglutide) subcutaneous** SYMLIN (pramlintide) subcutaneous* KAZANO (alogliptin/metformin)QL KOMBIGLYZE XR (saxagliptin/metformin)QL NESINA (alogliptin)QL ONGLYZA (saxagliptin)QL OSENI (alogliptin/pioglitazone)QL APIDRA (insulin glulisine) NOVOLIN (insulin) NOVOLOG (insulin aspart) NOVOLOG MIX (insulin aspart/aspart protamine) Insulin pens /cartridges* nateglinide (generic for Starlix) PRANDIMET (repaglinide/metformin) repaglinide (generic for Prandin) metformin ER (generic for Fortamet) GLUMETZA (metformin extended release) RIOMET (metformin oral solution) HYPOGLYCEMICS, METFORMINS (Implementation 07/17/2014) glipizide/metformin glyburide/metformin (generic for Glucovance) metformin (generic for Glucophage) metformin ER (generic for Glucophage XR) HYPOGLYCEMICS, SGLT2 (Implementation 07/17/2014) FARXIGA (dapagliflozin)* INVOKAMET (canagliflozin/metformin)NR INVOKANA (canagliflozin)* JARDIANCE (empagliflozin)NR XIGDUO XR (dapagliflozin/metformin)NR THIAZOLIDINEDIONES (TZDs) pioglitazone (generic for Actos) AVANDIA (rosiglitazone) HYPOGLYCEMICS, TZDs (Implementation 07/17/2014) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 15 THERAPEUTIC DRUG CLASS PREFERRED DRUGS NON-PREFERRED DRUGS TZD COMBINATIONS ACTOPLUS MET XR (pioglitazone/metformin) AVANDAMET (rosiglitazone/metformin) AVANDARYL (rosiglitazone/glipizide) pioglitazone/glimepiride (generic for Duetact) pioglitazone/metformin (generic for Actoplus Met) Hypoglycemics: Additional Classes The following hypoglycemic classes and the drugs noted are not reviewed by the PDL process but are covered without prior authorization. HYPOGLYCEMICS, SULFONYLUREAS IMMUNOMODULATORS, ATOPIC DERMATITIS (Implementation 01/08/2015) IMMUNOMODULATORS, TOPICAL (Implementation 01/08/2015) INTRANASAL RHINITIS DRUGS (Implementation 01/08/2015) IRRITABLE BOWEL SYNDROME (Implementation 07/17/2014) chlorpropamide glimepiride (generic for Amaryl) glipizide (generic for Glucotrol) glipizide ER (generic for Glucotrol XL) glyburide/micronized (generic for Diabeta, Glynase) tolazamide tolbutamide ELIDEL (pimecrolimus) ALDARA (imiquimod) PROTOPIC (tacrolimus)* imiquimod (generic for Aldara) ZYCLARA (imiquimod) ANTICHOLINERGICS ipratropium (generic for Atrovent) ANTIHISTAMINES ASTEPRO (azelastine) azelastine (generic for Astelin) PATANASE (olopatadine) azelastine (generic for Astepro) DYMISTA (azelastine/fluticasone) olopatadine (generic for Patanase) CORTICOSTEROIDS fluticasone (generic for Flonase) BECONASE AQ (beclomethasone) NASONEX (mometasone) budesonide (generic for Rhinocort Aqua) flunisolide (generic for Nasalide) OMNARIS (ciclesonide) QNASL (beclomethasone) triamcinolone (generic for Nasacort AQ) VERAMYST (fluticasone) ZETONNA (ciclesonide) AMITIZA (lubiprostone) LOTRONEX (alosetron) LINZESS (linaclotide) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 16 THERAPEUTIC DRUG CLASS LEUKOTRIENE MODIFIERS (Implementation 01/08/2015) LIPOTROPICS, OTHER (non-statins) (Implementation 07/17/2014) Note: Several other forms of OTC niacin and fish oil are also covered under Medicaid with a prescription without prior authorization. PREFERRED DRUGS ACCOLATE (zafirlukast) montelukast tablets (generic for Singulair) (chewable and swallow tablets) NON-PREFERRED DRUGS montelukast GRANULES (generic for Singulair Granules) zafirlukast (generic for Accolate) ZYFLO (zileuton) ZYFLO CR (zileuton) BILE ACID SEQUESTRANTS colestipol (generic for Colestid) cholestyramine (generic for Questran) GRANULES colestipol (generic for Colestid) TABLETS QUESTRAN LIGHT (cholestyramine) WELCHOL (colesevalam) TREATMENT OF HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA JUXTAPID (lomitapide)* KYNAMRO (mipomersen)* FIBRIC ACID DERIVATIVES fenofibrate (generic for Tricor) fenofibrate (generic for Antara) fenofibric acid (generic for Trilipix) fenofibrate (generic for Lofibra) gemfibrozil (generic for Lopid) fenofibric acid (generic for Fibricor) LIPOFEN (fenofibrate) LOFIBRA (fenofibrate) TRICOR (fenofibrate) TRIGLIDE (fenofibrate) TRILIPIX (fenofibric acid) NIACIN NIACOR (niacin IR) ADVICOR (lovastatin/niacin ER) NIASPAN (niacin ER) niacin ER (generic for Niaspan) OMEGA-3 FATTY ACIDS omega-3 fatty acids (generic for Lovaza) If triglycerides ≥ 500. (verified by faxed copy of lab report) LIPOTROPICS, STATINS (Implementation 07/17/2014) VASCEPA (icosapent) CHOLESTEROL ABSORPTION INHIBITORS ZETIA (ezetimibe) STATINS atorvastatin (generic for Lipitor) ALTOPREV (lovastatin) CRESTOR (rosuvastatin)* fluvastatin (generic for Lescol) lovastatin (generic for Mevacor) LESCOL / XL (fluvastatin) pravastatin (generic for Pravachol) LIVALO (pitavastatin) simvastatin (generic for Zocor) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 17 THERAPEUTIC DRUG CLASS MACROLIDES AND KETOLIDES (Oral) (Implementation 07/17/2014) MULTIPLE SCLEROSIS DRUGS (Implementation 07/17/2014) NSAID (Implementation 01/08/2015) https://nebraska.fhsc.com/Downl oads/NEfaxform_CoxII201311.pdf PREFERRED DRUGS NON-PREFERRED DRUGS STATIN COMBINATIONS ADVICOR (lovastatin/niacin ER) atorvastatin/ amlodipine (generic for CADUET) LIPTRUZET (ezetimibe/atorvastatin) SIMCOR (simvastatin/niacin ER) VYTORIN (simvastatin/ezetimibe) KETOLIDES KETEK (telithromycin) MACROLIDES azithromycin (generic for Zithromax) ERYTHROCIN EES 400 TABLET clarithromycin ER (generic for Biaxin XL) erythromycin base TABLET clarithromycin IR (generic for Biaxin) erythromycin base CAPSULE DR clarithromycin suspension ERYTAB ZMAX (azithromycin ER) EES 200 SUSPENSION ZITHROMAX (azithromycin) ERYPED 200 SUSPENSION ERYPED 400 SUSPENSION PCE (erythromycin) AUBAGIO (teriflunomide) AMPYRA (dalfampridine) AVONEX (interferon beta-1a) BETASERON (interferon beta-1b) COPAXONE 20mg Syringe Kit (glatiramer) COPAXONE 40mg Syringe (glatiramer) EXTAVIA (interferon beta-1b) GILENYA (fingolimod) PLEGRIDY (peginterferon beta-1a)NR REBIF (interferon beta-1a) TECFIDERA (dimethyl fumarate) COX-I SELECTIVE diclofenac potassium (generic for Cataflam) diclofenac SR (generic for Voltaren-XR) diclofenac sodium (generic for Voltaren) diflunisal (generic for Dolobid) etodolac (generic for Lodine) flurbiprofen (generic for Ansaid) ibuprofen OTC, Rx (generic for Advil, Motrin) etodolac SR indomethacin capsules (generic for Indocin) fenoprofen (generic for Nalfon) indomethacin ER (generic for Indocin) ketoprofen (generic for Orudis) INDOCIN RECTAL ketorolac (generic for Toradol) INDOCIN SUSPENSION meclofenamate (generic for Meclomen) ketoprofen ER meloxicam tablet (generic for Mobic) mefenamic acid (generic for Ponstel) nabumetone (generic for Relafen) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. THERAPEUTIC DRUG CLASS NSAID (topical) (Implementation 01/08/2015) PREFERRED DRUGS naproxen Rx, OTC (generic for Naprosyn) naproxen suspension (Naprosyn) sulindac (generic for Clinoril) 18 NON-PREFERRED DRUGS meloxicam suspension (generic Mobic) naproxen enteric coated oxaprozin (generic for Daypro) piroxicam (generic for Feldene) tolmetin (generic for Tolectin) ALL BRAND NAME NSAIDs ARE NONPREFERRED including: CAMBIA (diclofenac oral solution) DUEXIS (ibuprofen/famotidine) SPRIX (ketorolac) VIMOVO (naprosyn/esomeprazole) ZIPSOR (diclofenac) ZORVOLEX (diclofenac) NSAID/GI PROTECTANT COMBINATIONS diclofenac/misoprostol (generic for Arthrotec) COX-II SELECTIVE CELEBREX (celecoxib) diclofenac (generic for Pennsaid Solution) FLECTOR PATCH (diclofenac) PENNSAID PUMP (diclofenac)NR VOLTAREN GEL (diclofenac) Note: other oral oncology agents not listed here may also be available. See https://nebraska.fhsc.com/default.asp for coverage information and prior authorization status for products not listed below. ONCOLOGY AGENTS, ORAL, BREAST CANCER (Implementation 01/08/2015) AROMATASE INHIBITORS anastrozole (generic for Arimidex) exemestane (generic for Aromasin) letrozole (generic for Femara) ANTIESTROGEN tamoxifen FARESTON (toremifene) Note: other oral oncology agents not listed here may also be available. See https://nebraska.fhsc.com/default.asp for coverage information and prior authorization status for products not listed below. ONCOLOGY AGENTS, ORAL (Implementation 01/08/2015) Anti-Androgens bicalutamide (generic for Casodex) FLUTAMIDE XTANDI (enzalutamide) ZYTIGA (abiraterone) NILANDRON (nilutamide) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 19 THERAPEUTIC DRUG CLASS PREFERRED DRUGS NON-PREFERRED DRUGS Kinase Inhibitors AFINITOR (everolimus) BOSULIF (bosutinib) CAPRELSA (vandetanib) COMETRIQ (cabozantinib) GILOTRIF (afatinib) GLEEVEC (imatinib) ICLUSIG (ponatinib) IMBRUVICA (irutinib) INLYTA (axitinib) JAKAFI (ruxolitinib) MEKINIST (trametinib) NEXAVAR (sorafenib) SPRYCEL (dasatinib) STIVARGA (regorafenib) SUTENT (sunitinib) TAFINLAR (dabrafenib) TARCEVA (erlotinib) TASIGNA (nilotinib) TYKERB (lapatinib) VOTRIENT (pazopanib) XALKORI (crizotinib) ZELBORAF (vemurafenib) ZYDELIG (idelalisib) ZYKADIA (ceritinib) ALKERAN (melphalan) ERIVEDGE (vismodegib) hydroxyurea (generic for Hydrea) mercaptopurine TEMODAR (temozolomide) XELODA (capecitabine) ZOLINZA (vorinostat) OPHTHALMICS, ANTIBIOTICS (Implementation 01/08/2015) AFINITOR DISPERZ* Others capecitabine (generic for Xeloda) temozolomide (generic for Temodar)* PURIXAN (mercaptopurine oral suspension) FLUOROQUINOLONES ciprofloxacin solution (generic for Ciloxan) BESIVANCE (besifloxacin) MOXEZA (moxifloxacin) CILOXAN (ciprofloxacin) ofloxacin (generic for Ocuflox) gatifloxacin 0.5% (generic for Zymaxid) VIGAMOX (moxifloxacin) levofloxacin generic MACROLIDES erythromycin AZASITE (azithromycin) AMINOGLYCOSIDES gentamicin drops and ointment GARAMYCIN (gentamicin) tobramycin (generic for Tobrex drops) TOBREX ointment (tobramycin) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. THERAPEUTIC DRUG CLASS OPHTHALMIC ANTIBIOTICSTEROID COMBINATIONS (Implementation 01/08/2015) OPHTHALMICS FOR ALLERGIC CONJUNCTIVITIS (Implementation 01/08/2015) OPHTHALMICS, ANTI-INFLAMMATORIES (Implementation 01/08/2015) 20 PREFERRED NON-PREFERRED DRUGS DRUGS OTHER OPHTHALMIC ANTIBIOTICS polymyxin B/trimethoprim (gen for Polytrim) bacitracin bacitracin/polymyxin B (generic Polysporin) NATACYN (natamycin)* neomycin/bacitracin/polymyxin B ointment neomycin/polymyxin B/gramicidin sulfacetamide drops (generic for Bleph10) sulfacetamide ointment BLEPHAMIDE (prednisolone and neomyxin/polymyxin/HC sulfacetamide) neomycin/bacitracin/poly/HC BLEPHAMIDE S.O.P. tobramycin/dexamethasone suspension neomycin/polymyxin/dexamethasone (generic for Tobradex) (generic for Maxitrol) TOBRADEX S.T. (tobramycin and dexamethasone) PRED-G DROPS SUSP (prednisolone and gentamicin) ZYLET (loteprednol, tobramycin) PRED-G OINT (prednisolone and gentamicin) sulfacetamide/prednisolone TOBRADEX OINTMENT (tobramycin and dexamethasone) TOBRADEX SUSPENSION (tobramycin and dexamethasone) ALREX (loteprednol 0.2%) ALOCRIL (nedocromil) cromolyn (generic for Opticrom) ALOMIDE (lodoxamide) ketotifen OTC (generic for Zaditor) azelastine (generic for Optivar) PATADAY (olopatadine 0.2%) BEPREVE (bepotastine besilate) EMADINE (emedastine) epinastine (generic for Elestat) LASTACAFT (alcaftadine) PATANOL (olopatadine 0.1%) CORTICOSTEROIDS dexamethasone (generic for Maxidex) DUREZOL (difluprednate) FLAREX (fluorometholone) fluorometholone 0.1% (generic for FML) FML FORTE (fluorometholone 0.25%) FML S.O.P. (fluorometholone 0.1% ointment) LOTEMAX drops (loteprednol 0.5%) MAXIDEX (dexamethasone) PRED MILD (prednisolone) FML (fluorometholone 0.1% drops) LOTEMAX OINTMENT, GEL (loteprednol) prednisolone acetate 1% (gen. for Omnipred, Pred Forte) prednisolone sodium phosphate 1% VEXOL (rimexolone) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 21 THERAPEUTIC DRUG CLASS OPHTHALMICS, GLAUCOMA DRUG (Implementation 01/08/2015) PREFERRED DRUGS NON-PREFERRED DRUGS NSAID diclofenac (generic for Voltaren) ACUVAIL (ketorolac 0.45%) flurbiprofen (generic for Ocufen) bromfenac 0.09% (generic for Bromday) ILEVRO (nepafenac 0.3%) ketorolac LS 0.4% (generic for Acular LS) ketorolac 0.5% (generic for Acular) NEVANAC (nepafenac) PROLENSA (bromfenac 0.07%) MIOTICS PHOSPHOLINE IODIDE (echothiophate pilocarpine iodide)NR PILOPINE HS SYMPATHOMIMETICS Alphagan P (brimonidine 0.15%) Alphagan P (brimonidine 0.1%) brimonidine 0.2% (generic for Alphagan) apraclonidine (generic for Iopidine) brimonidine P 0.15% (gen for Alphagan P) BETA BLOCKERS BETOPTIC S (betaxolol) betaxolol (generic for Betoptic) carteolol (generic for Ocupress) TIMOPTIC OCUDOSE ISTALOL (timolol) TIMOPTIC XE (timolol gel forming solution) levobunolol (generic for Betagan) metipranolol (generic for Optipranolol) timolol (generic for Timoptic) CARBONIC ANHYDRASE INHIBITORS AZOPT (brinzolamide) TRUSOPT (dorzolamide) dorzolamide (generic for Trusopt) OTIC ANTIBIOTICS (Implementation 01/08/2015) PROSTAGLANDIN ANALOGS latanoprost (generic for Xalatan) LUMIGAN (bimatoprost) TRAVATAN Z (travoprost) RESCULA (unoprostone isopropyl) travoprost (generic for Travatan) XALATAN (latanoprost) ZIOPTAN (tafluprost) COMBINATION DRUGS dorzolamide/timolol (generic for Cosopt) COMBIGAN (brimonidine/timolol) SIMBRINZA (brinzolamide/brimonidine) COSOPT (dorzolamide/timolol) CIPRODEX (ciprofloxacin/dexamethasone) CIPRO HC (ciprofloxacin/hydrocortisone) neomycin/polymyxin/hydrocortisone COLY-MYCIN S (generic for Cortisporin) (neomycin/hydrocortisone/colistin) ofloxacin (generic for Floxin) CORTISPORIN-TC (neomycin/hydrocortisone/colistin) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. THERAPEUTIC DRUG CLASS OTIC ANTI INFECTIVES & ANESTHETICS (Implementation 01/08/2015) PANCREATIC ENZYMES (Implementation 07/17/2014) PHOSPHATE BINDERS (Implementation 07/17/2014) PLATELET AGGREGATION INHIBITORS (Implementation 07/17/2014) PULMONARY ARTERIAL HYPERTENSION AGENTS (Oral and inhaled) (Implementation 07/17/2014) PROTON PUMP INHIBITORS (ORAL) (Implementation 07/17/2014) SEDATIVE HYPNOTICS (Implementation 01/08/2015) 22 NON-PREFERRED DRUGS acetic acid/aluminum (generic for Otic Domeboro) acetic acid/hydrocortisone (generic for Vosol HC) CREON PANCREAZE (pancrelipase) PANCRELIPASETM (pancrelipase) PERTZYE (pancrelipase) ZENPEP (pancrelipase) ULTRESA (pancrelipase) VIOKACE (pancrelipase) calcium acetate TABLET calcium acetate CAPSULE CALPHRON OTC (calcium acetate) FOSRENOL (lanthanum) ELIPHOS (calcium acetate) PHOSLO (calcium acetate) PHOSLYRA (calcium acetate) RENVELA (sevelamer carbonate) RENAGEL (sevelamer HCl) VELPHORO (sucroferric oxyhydroxide) AGGRENOX (dipyridamole/aspirin) BRILINTA (ticagrelor)* aspirin EFFIENT (prasugrel)* clopidogrel (generic for Plavix) ticlopidine (generic for Ticlid) dipyridamole (generic for Persantine) ZONTIVITY (vorapaxar)NR LETAIRIS (ambrisentan) ADCIRCA (tadalafil) (for PAH only)* sildenafil (generic for Revatio) (for PAH only*) ADEMPAS (riociguat) TRACLEER (bosentan) OPSUMIT (macitentan) TYVASO INHALATION (treprostinil) ORENITRAM ER (treprostinil)NR VENTAVIS INHALATION (iloprost) REVATIO SUSPENSION (for PAH only*) omeprazole (generic for Prilosec) RX only DEXILANT (dexlansoprazole) pantoprazole (generic for Protonix) esomeprazole strontium lansoprazole (generic for Prevacid) NEXIUM (esomeprazole) NEXIUM SUSPENSION (esomeprazole) omeprazole/sodium bicarbonate (generic for Zegerid RX) PREVACID Rx, SOLU-TAB (lansoprazole) PRILOSEC (omeprazole) rabeprazole (generic for Aciphex) BENZODIAZEPINES estazolam (generic for ProSom) flurazepam (generic for Dalmane) temazepam 15mg, 30mg temazepam 7.5mg, 22.5mg (generic for Restoril) triazolam (generic for Halcion) PREFERRED DRUGS acetic acid (generic for Vosol) antipyrine/benzocaine (generic similar to Auralgan) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 23 THERAPEUTIC DRUG CLASS SKELETAL MUSCLE RELAXANTS (Implementation 07/17/2014) STEROIDS TOPICAL (Implementation 01/08/2015) PREFERRED DRUGS NON-PREFERRED DRUGS OTHERS zaleplon (generic for Sonata) EDLUAR (zolpidem sublingual) zolpidem (generic for Ambien) eszopiclone (generic for Lunesta) HETLIOZ (tasimelteon)* INTERMEZZO (zolpidem) ROZEREM (ramelteon) SILENOR (doxepin) zolpidem ER (generic for Ambien CR) ZOLPIMIST(zolpidem oral spray) baclofen (generic for Lioresal) AMRIX (cyclobenzaprine)* chlorzoxazone (generic for Parafon) carisoprodol (generic for Soma) cyclobenzaprine (generic for Flexeril) carisoprodol compound methocarbamol (generic for Robaxin) dantrolene (generic for Dantrium) tizanidine TABLETS (generic for Zanaflex) LORZONE (chlorzoxazone)* metaxalone (generic for Skelaxin) orphenadrine (generic for Norflex) orphenadrine compound PARAFON FORTE (chlorzoxazone) SOMA (carisoprodol)* tizanidine CAPSULES ZANAFLEX (tizanidine) (brand name tablets and capsules) LOW POTENCY hydrocortisone cream , ointment alclometasone dipropionate (generic for Aclovate) (generic for Cortaid) CAPEX Shampoo (fluocinolone) hydrocortisone OTC lotion DESONATE (desonide gel) hydrocortisone/aloe ointment, cream desonide lotion (generic for Desowen) desonide cream, ointment (generic for former products Desowen, Tridesilon) fluocinolone 0.01% OIL ( generic for DERMA-SMOOTHE-FS) hydrocortisone Rx lotion hydrocortisone/aloe gel hydrocortisone/urea TEXACORT (hydrocortisone) VERDESO (desonide) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 24 THERAPEUTIC DRUG CLASS PREFERRED DRUGS NON-PREFERRED DRUGS MEDIUM POTENCY betamethasone valerate (generic fluticasone propionate cream/ointment for Luxiq) (generic for Cutivate) clocortolone (generic for CLODERM) mometasone furoate cream, solution, CORDRAN TAPE (flurandrenolide) ointment (generic for Elocon) fluocinolone acetonide (generic for Synalar) fluticasone propionate lotion (generic for Cutivate) hydrocortisone butyrate (generic for Locoid) hydrocortisone butyrate/emoll (generic for Locoid Lipocream) hydrocortisone valerate (generic for Westcort) MOMEXIN (mometasone) PANDEL (hydrocortisone probutate 0.1%) prednicarbate (generic for Dermatop) HIGH POTENCY amcinonide cream, ointment, lotion betamethasone valerate (generic for Beta-Val) betamethasone dipropionate fluocinonide cream, ointment, gel (generic for Diprolene) betamethasone dipro/prop gly fluocinonide emollient (augmented) triamcinolone acetonide ointment, cream desoximetasone (generic for Topicort) (generic for Kenalog) diflorasone diacetate fluocinonide SOLUTION HALOG (halcinonide) KENALOG AEROSOL (triamcinolone) triamcinolone lotion TRIANEX Ointment (triamcinolone) VANOS (fluocinonide) VERY HIGH POTENCY clobetasol emollient (generic for Temovate-E) APEXICON-E (diflorasone) clobetasol shampoo, lotion clobetasol propionate (generic for Temovate) halobetasol propionate (generic for Ultravate) clobetasol propionate FOAM CLOBEX (clobetasol) OLUX-E (clobetasol) OLUX/OLUX-E CP (clobetasol) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 25 THERAPEUTIC DRUG CLASS STIMULANTS AND RELATED ADHD DRUGS (Implementation 01/08/2015) Note: Patients on nonpreferred stimulants prior to the PDL are eligible for “grandfathering.” QL= quantity limits may apply to this class. PREFERRED DRUGS NON-PREFERRED DRUGS CNS STIMULANTS Amphetamine type ADDERALL XR (amphetamine salt combo) amphetamine salt combination ER amphetamine salt combination IR (generic for Adderall XR) dextroamphetamine (generic for Dexedrine) VYVANSE (lisdexamfetamine) dextroamphetamine solution (generic for Procentra) dextroamphetamine ER (generic for Dexedrine ER) methamphetamine (generic for Desoxyn) ZENZEDI (dextroamphetamine) Methylphenidate type FOCALIN (dexmethylphenidate) dexmethylphenidate (generic for Focalin) FOCALIN XR (dexmethylphenidate) dexmethylphenidate XR (generic for ------------------------------------------------------------Focalin XR) METHYLIN CHEWABLE (methylphenidate) --------------------------------------------------------methylphenidate (generic for Ritalin) methylphenidate solution ------------------------------------------------------------- METHYLIN SOLUTION (methylphenidate) RITALIN (methylphenidate) methylphenidate ER 10mg, 20mg (generic for Ritalin-SR, Metadate ER) -------------------------------------------------------------------------------------------------------------------- DAYTRANA (methylphenidate patch) QUILLIVANT XR (methylphenidate methylphenidate 30/70 (generic for suspension) Metadate CD) methylphenidate 50/50 (generic for RITALIN LA) methylphenidate ER (generic for Ritalin-SR) --------------------------------------------------------CONCERTA (methylphenidate ER 18mg, 27mg, 36mg, 54mg) methylphenidate ER 18mg, 27mg, 36mg, 54mg (generic Concerta) MISCELLANEOUS Note: generic guanfacine and clonidine INTUNIV (guanfacine extended release)* are available without prior authorization. clonidine ER (generic for Kapvay)* STRATTERA (atomoxetine) ANALEPTICS modafanil (generic for Provigil)* NUVIGIL (armodafinil)* BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply. 26 THERAPEUTIC DRUG CLASS TETRACYCLINES (Implementation 07/17/2014) ULCERATIVE COLITIS (Implementation 07/17/2014) PREFERRED DRUGS NON-PREFERRED DRUGS doxycycline hyclate IR (generic for Vibramycin) doxycycline monohydrate 50MG, 100MG capsules minocycline HCl capsules (generic for Minocin, Dynacin) tetracycline HCl (generic for Sumycin) demeclocycline* DORYX (doxycycline pelletized) doxycycline hyclate DR (generic for Vibratabs) doxycycline monohydrate TABLET, SUSPENSION, 75MG and 150MG CAPSULES (Monodox, Adoxa) doxycycline monohydrate (generic for Oracea) minocycline HCl tablets (generic for Dynacin, Murac) minocycline HCl extended release (generic for Solodyn) ORACEA (doxycycline monohydrate) SOLODYN (minocycline HCl) VIBRAMYCIN SUSPENSION (doxycycline) ORAL ASACOL HD 800mg (mesalamine) APRISO (mesalamine) ASACOL (mesalamine) 400MG DELZICOL DR (mesalamine) balsalazide (generic for Colazal) DIPENTUM (olsalazine) sulfasalazine / DR (generic for Azulfidine) GIAZO (balsalazide) LIALDA (mesalamine) PENTASA (mesalamine) UCERIS ORAL (budesonide)NR UCERIS RECTAL FOAM (budesonide)NR RECTAL CANASA (mesalamine) mesalamine SFROWASA (mesalamine) BRAND PRODUCTS IN UPPER CASE generic names in lower case. If only the generic name is listed as preferred, then the BRAND name of that product is nonpreferred; unless the brand name product is ALSO listed as preferred. *Indicates that a clinical prior authorization is required despite the medication’s status as preferred or non-preferred. QL indicates quantity limits. NR indicates product was not reviewed. New Drug criteria will apply.
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