154B Brook Drive Milton Park Oxfordshire OX14 4SD United Kingdom Tel: +44 (0)1235 835328 Job Title: Process Development Associate Scientist/Scientist PsiOxus Therapeutics Ltd is an Oxford based development stage biotechnology company developing novel therapeutics with a particular focus upon cancer. We currently have two products in phase I/II clinical development and an innovative pipeline of research stage candidates. We have an exciting opportunity for a scientist with experience in process development to join us and be part of a development team responsible for delivering improvements to the manufacturing process for our present clinical stage oncolytic vaccine as well as the next generation of viral cancer therapies. The successful candidate will report to the VP Pharmaceutical Development and thrive in a creative and fast-paced environment. By taking responsibility for key aspects of process development and supporting our R&D activities you will have the opportunity to work across a wide range of techniques from the culture of viruses, cell lines, up-stream & down-stream development and use of biological and immunological assays to assess the manufactured product. Applicants must have a relevant life sciences degree followed by a minimum of one year demonstrable practical experience of mammalian cell culture & small scale (3 – 5 L) bioreactor manufacture. A proficient understanding of the bioreactor controller is also desirable. Proven ability to work and communicate effectively as part of a team is essential, together with clear attention to detail and an ability to meticulously and independently follow protocols, carry out and record experiments. The successful candidate will be enthusiastic and diligent in their approach to work and have one or more of the following desirable additional experience and skills: small-scale purification, optimisation and scale-up of purification processes and experience of analytical assays (e.g. HPLC, immunoassays, cell-based infectivity assays). We offer an attractive remuneration package including salary, pension and other benefits. For further details please send your CV along with a cover letter, briefly outlining why you believe you are the right candidate, to: Mine McPherson, at [email protected] adding ‘Process Development Scientist Application’ to the subject line of your email. Closure date for applications is 27th March 2015 Please note that unless you specify in your email, all applications will be kept on the confidential company database in case of future opportunities