Ther-Biotic® Children’s Chewable is a broad-spectrum, hypoallergenic probiotic supplement designed for children two years of age and older. The convenient, naturally flavored chewable tablets deliver potent amounts of 4 Lactobacillus and 4 Bifidobacterium species that benefit gastrointestinal, immune, and oral health in children. Use of xylitol, a natural sweetener that discourages plaque formation and dental caries, offers added benefits for oral health. Ther-Biotic® Children’s Chewable High-Potency, Multispecies Chewable Probiotic Supports gastrointestinal health. Gastrointestinal disorders are common in children and may range from mild bouts of constipation, diarrhea, and stomach upset to more serious conditions such as IBD and celiac disease. The eight probiotic species in Ther-Biotic® Children’s Chewable work together to help normalize intestinal motility, modulate inflammation within the gut, and antagonize pathogenic organisms by directly competing for nutrients and living space as well as secreting antimicrobial substances such as bacteriocins and hydrogen peroxide. Supports normal maturation of a child’s immune system. Normal maturation of the immune system is highly dependent upon development of a healthy intestinal microbiota. However, children’s immune systems are continuously challenged by infectious microbes, allergens and irritants in foods, chemical toxins, and overuse of medications that can easily disrupt intestinal microbalance. The substantial amounts of Lactobacillus and Bifidobacterium in this formula support a normal microflora as well as augment multiple aspects of immune function including antibody production, leukocyte phagocytic activity, and natural killer cell cytotoxicity. Promotes immunotolerance. Ther-Biotic® Children’s Chewable provides a variety of probiotic species that support appropriate immune responses by balancing T helper (Th1, Th2, and Th17) activity and inducing secretion of regulatory cytokines from T regulatory (Treg) cells. Probiotics included also contribute to immune tolerance by limiting exposure to environmental antigens through enhanced integrity of the intestinal mucosal barrier and breakdown of immune-provoking peptides such as found in casein and gluten. Provides additional benefit for oral health. Tooth decay and gingivitis are highly prevalent among both children and adolescents. Ther-Biotic® Children’s Chewable provides Lactobacillus species that normally reside in the oral cavity and antagonize oral pathogens associated with dental caries and gingivitis, such as Streptococcus mutans and Porphyromonas gingivalis. Use of xylitol, a natural sweetener shown to inhibit formation of plaque and dental caries, adds extra benefits for oral care. Ther-Biotic® Children’s Chewable tablets facilitate prolonged contact of the probiotics and xylitol with the oral cavity. • Suitable for children over age 2, or even adults • Supplies 25+ billion CFUs per tablet • Hypoallergenic, dairy- and gluten-free • Great tasting, natural cherry flavor Available exclusively through licensed healthcare professionals. ® A d i v i s i o n o f P r oT h e r a ® , I n c . Ther-Biotic® Children’s Chewable High-Potency, Multispecies Chewable Probiotic INDICATIONS Ther-Biotic® Children’s Chewable is designed to support a healthy intestinal microflora in children aged two and older. Children with gastrointestinal complaints such as constipation, diarrhea, or functional abdominal pain may benefit the most from this formula. Ther-Biotic® Children’s Chewable is also recommended for children susceptible to frequent respiratory infections or allergies and is particularly indicated for those taking medications harmful to the intestinal flora, such as antibiotics. Regular use of Ther-Biotic® Children’s Chewable can promote oral health by inhibiting the growth of pathogenic microorganisms associated with dental caries and periodontal disease. ABOUT PROTHERA®, INC. ProThera®, Incorporated manufactures a complete line of nutraceutical products from the brands healthcare professionals trust and recommend with confidence. Products are designed for clinical application and are available exclusively through healthcare professionals. Full private labeling and custom manufacturing services are available. ProThera®, Inc. is a subsidiary company of Soho Flordis International Pty Ltd. OUR BRANDS ProThera brand integrated formulas build ® upon versatile multiple vitamin/mineral FORMULA supplements with focused multi- and Supplement Facts Serving Size 1 Tablet • Servings Per Container 60 Amount Per Tablet Probiotic Blend (25+ billion CFUs) 224 mg* in a base of inulin (derived from chicory root) Lactobacillus species 17+ billion CFUs* Lactobacillus rhamnosus Lactobacillus casei Lactobacillus salivarius Lactobacillus paracasei Bifidobacterium species 8+ billion CFUs* Bifidobacterium infantis Bifidobacterium bifidum Bifidobacterium longum Bifidobacterium breve *Daily Value not established. Other ingredients: Xylitol, natural cherry flavor, natural vanilla flavor, silicon dioxide, stearic acid, magnesium stearate, and natural licorice extract. SUGGESTED USE As a dietary supplement chew one tablet daily preferably 30-60 minutes following a meal or as directed by a healthcare practitioner. For maximum benefit, chew tablet slowly to allow for increased contact between the ingredients in Ther-Biotic® Children’s Chewable and the tissues of the oral cavity. ADVERSE REACTIONS Ingestion of Lactobacillus and Bifidobacterium probiotics may sometimes be associated with bloating and gas. They are regarded as safe and nonpathogenic although rarely associated with opportunistic infections in compromised hosts. single-ingredient products to address a variety of metabolic concerns. Klaire Labs® brand specializes in hypoallergenic pre- and probiotics, enzymes, and specialty formulas for GI and immune support that can be used with confidence by individuals who are hypersensitive to various foods and environmental agents. Complementary Prescriptions™ brand centers on a modular concept that utilizes foundational products for total wellness, protocol formulas for targeted support, and synergistic antioxidants, hormones, and energizers to create effective anti-aging programs. CONTACT US 888-488-2488 • www.protherainc.com 10439 Double R Blvd, Reno, NV 89521 ProThera®, Inc. operates a GMP 9000 registered facility certified by NSF® International, an independent, third-party certification organization. GMP 9000 registration integrates both ISO 9001 and GMP registration. DRUG INTERACTIONS None reported. CONTRAINDICATIONS Individuals sensitive to chicory root (inulin source) may wish to avoid use of this product. HOW SUPPLIED 60 chewable tablets per bottle with full-bottle shrinkwrap. Packaged 12 bottles per case. STORAGE This product contains live bacterial cultures that require refrigeration during storage to maintain maximum potency. Ther-Biotic® Children’s Chewable is shipped with temperature-control packs, however, short-term exposures to warmer temperatures will typically not adversely affect potency. Refrigeration is recommended during storage to maintain maximum viability of the live microorganisms over time. Statements made herein have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. ©Copyright 2010-2014 ProThera®, Inc. Reno, NV All rights reserved. KTCCPROFFLY0812 14w