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Biomarkers in Heart Failure and
Acute Coronary Syndromes:
Diagnosis, Treatment and Devices
Friday, March 13, 2015
Estancia La Jolla Hotel
La Jolla, California
PAID
11TH ANNUAL
This annual event is designed to provide the latest clinical data, guidelines and evidence related to the clinical application of cardiac biomarkers. Topics cover state
of the art application of biomarkers in the following clinical categories:
• 2013 ACC/AHA guidelines and the integration of new biomarkers and new
application of existing biomarkers
• Examination of the evolving utility of cardiac necrosis biomarkers in Acute
Coronary Syndromes and Heart Failure
• Review of the latest clinical data associated with biomarkers in
cardiovascular disease risk prediction and clinical management of disease.
• Integration of biomarker data in comorbid conditions including renal
disease, diabetes and pulmonary disease
• The application of biomarkers in therapeutic and device trials as
qualification criteria, surrogate endpoints, etc.
Permit No. 113
San Diego, CA
COURSE DESCRIPTION
Non-Profit Org
U.S. Postage
ABOUT THE SYMPOSIUM
OBJECTIVES
At the conclusion of this activity, participants should be able to:
TARGET AUDIENCE
The target audience for this activity includes Cardiologists, Internists, Primary Care Physicians,
Emergency Medicine Physicians, Clinical Laboratorians and Nursing Professionals.
PLEASE POST
The content of this educational activity was determined by a rigorous review of recent medical literature as well as the changes in biomarker evidence, use and guidelines in the United
States over the past 3 years. Evidence-based medical education is of significant importance to
the target clinical audience across the US including but not limited to San Diego & Los Angeles.
If you receive more than one brochure,
won’t you pass the extra along to an associate?
Officially endorsed by the Heart Failure Society of America. The opinions presented in this educational activity do not necessarily reflect the
opinions or recommendations of the HFSA.
In other related cardiovascular conditions such as acute coronary syndromes biomarkers have
played a definitive diagnostic role yet confusion has evolved as the sensitivity of biomarkers
such as cardiac troponin have improved. These new and evolving issues are critical for clinicians to be prepared to interpret at the point of care.
Estancia La Jolla Hotel
La Jolla, California
HFSA
The diagnosis and management of cardiovascular conditions by clinical means alone is often
inadequate, including but not limited to heart failure. Until recently, biomarker testing in heart
failure (HF) syndromes has been viewed as an elective supplement to diagnostic evaluation of
patients suspected to suffer from this condition. This approach to the use of biomarker testing
contrasts with other cardiovascular diagnoses for which biomarkers are integral to disease
process definition, risk stratification, and in some cases treatment decision making. It is also
noteworthy that advanced guidelines have emerged regarding the application of biomarkers in
heart failure4that need to be integrated into educational initiatives for clinical caregivers.
Friday, March 13, 2015
This activity is in compliance with California Assembly Bill 1195 which
requires continuing medical education activities with patient care components to include curriculum in the subjects of cultural and linguistic
competency. Cultural competency is defined as a set of integrated attitudes, knowledge, and skills that enables health care professionals or
organizations to care effectively for patients from diverse cultures,
groups, and communities. Linguistic competency is defined as the ability
of a physician or surgeon to provide patients who do not speak English
or who have limited ability to speak English, direct communication in
the patient’s primary language. Cultural and linguistic competency was
incorporated into the planning of this activity.Additional resources on
cultural and linguistic competency and information about AB1195
can be found on the UCSD CME website at http://cme.ucsd.edu.
Cardiovascular disease (CVD) is the leading cause of death in the United States and is responsible for 17% of national health expenditures. As the population ages, these costs are expected to increase substantially. This program is intended to interpret the current standards of
care associated with the application of biomarkers in cardiac clinical care as well as review
recent literature that provides evidence-basis for the diagnostic, prognostic and management
application of cardiac biomarkers.
Biomarkers in Heart Failure and
Acute Coronary Syndromes:
Diagnosis, Treatment and Devices
Cultural and Linguistic Competency
NEEDS ASSESSMENT
11TH ANNUAL
It is our policy to ensure balance, independence, objectivity and scientific
rigor. All persons involved in the selection, development and presentation of content are required to disclose any real or apparent conflicts of
interest. All conflicts of interest will be resolved prior to an educational
activity being delivered to learners through one of the following
mechanisms 1) altering the financial relationship with the commercial
interest, 2) altering the individual’s control over CME content about the
products or services of the commercial interest, and/or 3) validating the
activity content through independent peer review. All persons are also
required to disclose any discussions of off label/unapproved uses of
drugs or devices. Persons who refuse or fail to disclose will be disqualified
from participating in the CME activity.
UC San Diego Health System
200 West Arbor Drive
San Diego, CA 92103-7411
Faculty Disclosure
1. Describe the current standards of care associated with the application of
biomarkers in cardiac clinical care.
2. Review recent literature that provides evidence-basis for the diagnostic,
prognostic and management application of cardiac biomarkers
3. Discuss the future biomarker applications in cardiac disease based on
breaking clinical studies and clinical trials.
PROGRAM
FACULTY
UC SAN DIEGO PROGRAM CO-DIRECTORS
Alan Maisel, MD, FACC
Lori Daniels, MD, FACC
Professor of Cardiology, UCSD
Director, Coronary Care Unit and
Heart Failure Program
San Diego Veterans Affairs Medical Center
Associate Professor of Medicine
Director, Coronary Care Unit
Division of Cardiology
Anthony N. DeMaria, MD, FACC
UC SAN DIEGO PARTICIPATING FACULTY
Eric Adler, MD
David Krummen, MD, FACC
Associate Clinical Professor
Medical Director, Cardiac Transplant
Associate Professor of Medicine
Director of Cardiac Electrophysiology
VA San Diego Healthcare System
Electrophysiologist, UCSD & VA San Diego
Daniel Blanchard, MD, FACC
Atul Malhotra, MD
Chief, Pulmonary & Critical Care Medicine
Director of Sleep Medicine
Kenneth M. Moser, Professor, Dept. of
Medicine, President, American Thoracic
Society (2015-2016)
Barry H. Greenberg, MD, FACC
Pam R. Taub, MD, FACC
Distinguished Professor of Medicine
Director, Advanced Heart
Failure Treatment Program
Assistant Professor of Medicine
GUEST FACULTY
Robert L. Jesse, MD, PhD, FACC
Executive Director, Clinical Trials Center
Cardiovascular Research Foundation
Columbia University
New York, NY
Professor of Medicine/Cardiology
Virginia Commonwealth University Health System
Richmond, VA
Chief, Office for Academic Affiliations, Veterans
Health Administration, Washington, DC
Christopher deFilippi, MD
John McMurray, MD, FACC
Associate Professor of Medicine
University of Maryland
Division of Cardiovascular Medicine
Baltimore, MD
Professor of Medical Cardiology
University of Glasgow
Glasgow, Scottland
Uri Elkayam, MD, FACC
David A Morrow, MD, MPH, FACC
Professor of Medicine
Keck School of Medicine
University of Southern California
Los Angeles, CA
Brigham and Women’s Hospital
Boston, MA
Gregg Fonarow, MD, FACC
William Franklin Peacock, IV,
MD, FACEP
Allan S. Jaffe, MD, FACC
8:30-8:45am
8:45-9:00am
9:00-9:15am
9:15-9:30am
Professor, Emergency Medicine
Associate Chair and Research Director
Baylor College of Medicine
Houston, TX
Nathan Wong, PhD, FACC, FAHA
Professor of Medicine, & Professor of
Laboratory Medicine and Pathology, Chair
CCLS Division, Department of Laboratory
Medicine and Pathology, Mayo Clinic and
Medical School, Rochester, MN
Professor and Director, Heart Disease
Prevention Program
Division of Cardiology
UC Irvine
Irvine, CA
James L Januzzi, MD, FACC
Alan Wu, PhD
Hutter Family Professor of Medicine
Harvard Medical School
Roman W DeSanctis Endowed Distinguished
Clinical Scholar
Massachusetts General Hospital, Boston, MA
Professor, of Laborary Medicine
UC San Francisco
San Francisco, CA
Registration/Coffee
Welcome - Anthony DeMaria, MD, Lori Daniels, MD, Etisham Mahmud, MD
and David Brenner, MD
Agenda Review and Introductions - Alan Maisel, MD
Biomarkers for Prediction and Prevention of Heart Disease
Lori Daniels, MD (Moderator)
Overview: Risk Prediction and Disease Prevention - Gregg Fonarow, MD
Physical Activity/Exercise and the Potential Role of Biomarkers
Christopher deFilippi, MD
Sorting Out Lipid Biomarkers - Ori Ben-Yehuda, MD
Imaging in CVD Risk Assessment: Implications of ACC/AHA Guidelines
Nathan Wong, MD
A New Biomarker for Women - Alan Maisel, MD
Panel Discussion and Case Presentations - Lori Daniels, MD and Panel
SESSION II
Biomarker Update in Acute Coronary Syndromes - Robert Jesse, MD (Moderator)
9:30-9:45am
9:45-10:00am
10:00-10:15am
10:15-10:30am
Chest Pain in the Emergency Department: Who gets What? - Frank Peacock, MD
hsTroponin and Chest Pain - State of the Art - Allan Jaffee, MD
Novel Biomakers in ACS - David Morrow, MD
Critical Analytical and Practical Issues in the Lab for ACS Biomarkers
Alan Wu, MD
Panel Discussion and Case Presentation - Robert Jesse, MD and Panel
Coffee Break/Visit Exhibits
SPECIAL RESEARCH PRESENTATIONS - Alan Maisel, MD, Moderator
TRAPID Study - Christopher deFilippi, MD
PARADIGM Trial - John McMurray, MD
Lunch/Visit Exhibits
10:30-11:00am
11:00-11:20am
Ori Ben-Yehuda, MD, FACC
Professor of Medicine, Director, AhmansonUCLA Cardiomyopathy Center
Co-Chief, UCLA Division of Cardiology
University of California, Los Angeles
Los Angeles, CA
SESSION I
7:50-8:00am
8:00-8:15am
8:15-8:30am
Judith and Jack White Chair in Cardiology
Professor of Medicine
Founding Director, Sulpizio Family
Cardiovascular Center
Professor of Medicine
Director, Cardiology
Fellowship Program
Sulpizio Cardiovascular Center
7:00 - 7:45 am
7:45am
11:20-11:45am
11:45-12:15pm
12:15-1:15pm
SESSION III
Acute Heart Failure - Alan Maisel, MD (Moderator)
1:15-1:30pm
1:30-1:45pm
1:45-2:00pm
2:00-2:15pm
2:15-2:30pm
2:30-2:45pm
Biomarkers of Diagnosis and Risk Stratification in AHF - Lori Daniels, MD
Treatment of AHF: What is New? - Barry Greenberg, MD
Biomarkers of AHF: Co-Morbidities, Hyponatremia, AKI - Uri Elkayam, MD
Role of Biomarkers in AHF: from Hospital to Home - Alan Maisel, MD
Panel Discussion and Case Presentation - Alan Maisel, MD and Panel
Coffee Break/Visit Exhibits
SESSION IV
Chronic Heart Failure - Anthony DeMaria, MD (Moderator)
2:45-3:00pm
3:00-3:15pm
3:15-3:30pm
3:30-3:45pm
3:45-4:00pm
4:00-4:15pm
4:15-4:30pm
4:30-4:45pm
4:45-5:00pm
5:00pm
5:00pm
Biomarker Guided Treatment - James Januzzi, MD
Nascent Heart Failure Therapy and the Arrival of Ivabradine - John McMurray, MD
Atrial Fibrillation Novel Anticoagulation Therapy - Daniel Blanchard, MD
Arrhythmias, Devices and Biomarkers - David Krummen, MD
Therapies for End Stage Heart Failure - Eric Adler, MD
Sleep Disordered Breathing in Heart Failure - Atul Malhotra, MD
LDL Particle Number and Cardiovascular Risk - Pam Taub, MD
Pulmonary Arterial Hypertension - New Therapies - Alan Wu, MD
Panel Discussion and Case Presentation - Anthony DeMaria, MD and Panel
Conclusion and Adjourn - Alan Maisel, MD
Reception
COURSE INFORMATION
ACCREDITATION
The University of California, San Diego School of Medicine is accredited by the Accreditation
Council for Continuing Medical Education to provide continuing medical education for physicians.
The University of California, San Diego School of Medicine designates this live activity for a
maximum of 7.5 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit
commensurate with the extent of their participation in the activity.
For the purpose of recertification, the American Nurses Credentialing Center accepts AMA PRA
Category 1 Credit(s)TM issued by organizations accredited by the ACCME. For the purpose of relicensure, the California Board of Registered Nursing accepts AMA PRA Category 1 Credit(s)TM
(report up to 7.5 hours of credit and list “CME Category 1” as the provider number).
REGISTRATION FEES
LOCATION
Friday, March 13, 2015
Estancia La Jolla Hotel
La Jolla, California
First Name _____________________________________________
Last Name _____________________________________________
Office Address _________________________________________
City __________________________________________________
State _________________________________________________
Zip ___________________________________________________
Phone ________________________________________________
Estancia La Jolla Hotel
9700 North Torrey Pines Road
La Jolla, CA 92037
Tel: 858-550-1000
Fax: 858-550-1001
1-877-4-ESTANCIA (toll free reservations)
www.Estancialajolla.com
Fax ___________________________________________________
Email__________________________________________________
Professional Specialty ____________________________________
Special room rates are offered:
Single or Double - $184 per night, plus
San Diego occupancy tax of 12.565%,
$8 hospitality fee and $10 overnight parking fee.
The site for the meeting is on 9.5 acres in the enchanting seaside community of La Jolla at the
new 21st Century Learning Retreat, the Estancia La Jolla Hotel. The hotel is in the midst of a
classic California coastal rancho setting, adjacent to world-class Torrey Pines Golf Course, and
just minutes from the San Diego Zoo, Sea World, shopping and beautiful Southern California
beaches. The hotel is only 14 miles from downtown San Diego and Lindbergh Field (San Diego
International Airport). A limited number of rooms have been reserved for course participants
and will be reserved as requests are received.
Reservation Deadline: February 19, 2015. If your reservation is not received prior to cutoff date, reservations will be accepted subject to availability. Please specify that you plan to attend
the 11TH BIOMARKERS in HEART DISEASE so you can receive our special course rate.
CONTACT THE HOTEL DIRECTLY TO MAKE RESERVATIONS
CANCELLATION POLICY
Special Needs for Disabled ________________________________
Registration Fees:
$100 Early Registration - on or before February 15, 2015
$125 Registration - after February 15, 2015 & on-site
$50 Nurse/Allied Early Registration - on or before February 15, 2015
$75 Nurse/Allied Registration - after February 15, 2015 & on-site
$50 Student Registration - with Student ID & letter from Dept Supervisor
CREDIT CARD PAYMENT (Visa, Mastercard, Am Exp or Discover)
Name of Registrant ______________________________________
Card Number __________________________________________
Security Code _______________Exp. Date____________________
Name on Card _________________________________________
Billing Address _________________________________________
______________________________________________________
If your registration must be cancelled and a refund of your fee is desired, your fee, less $50
for administrative costs, will be refunded upon receipt of a written request that includes your
signature. No refunds will be made after February 15, 2015. Please allow up to 12 weeks
for a refund.
Complete Conference Management
3320 Third Avenue, Suite C
San Diego, CA 92103
Websites: www.ccmmeetings.com
Biomarkers in Heart Failure and
Acute Coronary Syndromes:
Diagnosis, Treatment and Devices
Title __________________________________________________
$100 Early Registration - on or before February 15, 2015
$125 Registration - after February 15, 2015 & on-site
$50 Nurse/Allied Early Registration - on or before February 15, 2015
$75 Nurse/Allied Registration - after February 15, 2015 & on-site
$50 Student Registration - with Student ID and a letter from Department Supervisor
FURTHER INFORMATION
REGISTRATION INFORMATION
Phone: 619-299-6673
Fax: 619-299-6675
Email: [email protected]
http://cardiology.ucsd.edu
Amount $ _____________________________________________
Signature _____________________________________________
Please do not send credit card information by fax.
CHECK OR MONEY ORDER PAYMENT (in US dollars)
Make payable to:
Send or Fax to:
UC Regents
Complete Conference Management
3320 Third Avenue, Suite C
San Diego, CA 92103
Fax: 619-299-6675