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EVALUATION OF RENAL FUNCTION AND RENAL RISK
IN THE TWENTY-FIRST CENTURY
CME course of the DIABESITY working group
Villa Camozzi, Ranica-Bergamo, Italy December 2015
Day 1: EVALUATIONOF RENAL FUNCTION
8:45 Welcome-Introduction (Esteban Porrini, Spain)
9:00 Lecture: “Measurement of renal function in clinical research”
(Giuseppe Remuzzi-Italy)
IMPACT OF THE BIAS OF ESTIMATED GFR IN NEPHROLOGY
9:40 “Glomerular hyperfiltration: its role in diabetic nephropathy”
(P. Ruggenenti, Italy)
10:10 “Obesity and renal disease” (Manuel Praga, Spain)
10:40 Coffee break
11:30 “Does eGFR detect hyperfiltration and changes in renal function in diabetes and
obesity? (Flavio Gaspari, Italy)
12:00 “Can we really evaluate the evolution of chronic nephropathies with formulas”
(Norberto Perico, Italy)
13:00 Lunch break
14:30 “Renal and non-renal transplantation” (Mads Hornum, Denmark)
15: 00 Beyond Nephrology: “Consequences of using estimated GFR in drug dosing
and drug monitoring” (Bo Feldt-Rasmussen, Denmark)
WHY FORMULAS FAIL?
15:30 The limitations of creatinine and cystatin C in reflecting renal function.
(Aiko De Vries).
16:30 Coffe break
METHODOLOGYCAL ASPECTS
17:00 “How to evaluate the agreement between a formula that estimate GFR” Introduction
to agreement methods for continuous measurements (Esteban Porrini, Spain)
17:30-19:00 ABSTRACTS SESSION
20:00 DINNER
Day 2: EVALUATION OF RENAL RISK IN DIABETES AND OBESITY
9:00 Overview: markers or renal disease in diabetes and obesity, where do we stand?
(Radovan Hojs, Slovenia)
ALBUMINURIA
9:30 Glomerular and tubular handling of albuminuria. (Norberto Perico, Italy)
TUBULAR MARKERS
10:00 Markers of fatty kidney: liver-type fatty acid binding protein (L-FABP) and free fatty
acids (Juan Gómez-Gerique, Santander-Spain)
10:30 Coffee break
11:00 New markers of tubular damage in diabetic nephropathy: kidney injury marker 1
(KIM-1), acetyl-β-d-glucosaminidasa (NGAL), α1 microglobulina. (to be confirmed).
INFLAMMATORY MARKERS
11:40: “Circulating TNF receptors as predictors of renal function decline in diabetes”
(Monika Niewczas, Poland)
13:00 Lunch
MICRO RNAs
14:30 Introduction to microRNAs (to be confirmed)
15:00 The role of microRNAs in renal disease. (A Benigni)
15:00 Concluding remarks