JASN December 2014 Vol. 25 No. 12 Journal of the American Society of Nephrology This Month’s Highlights 2717 .MicroRNA-24 Antagonism Prevents Renal Ischemia Reperfusion Injury Johan M. Lorenzen, Tamas Kaucsar, Celina Schauerte, Roland Schmitt, Song Rong, Anika H€ ubner, Kristian Scherf, Jan Fiedler, Filippo Martino, Regalla Kumarswamy, Malte Kölling, Inga Sörensen, Hebke Hinz, Joerg Heineke, Eva van Rooij, Hermann Haller, and Thomas Thum UP FRONT MATTERS 2679 Editorials Renal Angiotensin-Converting Enzyme Upregulation: A Prerequisite for Nitric Oxide Synthase Inhibition–Induced Hypertension? Lodi C.W. Roksnoer, Ewout J. Hoorn, and A.H. Jan Danser · 2681 See related article by Giani et al. (pp. 2752–2763). · 2740 See related article by Hanatani et al. (pp. 2800–2811). Asking Dialysis Patients About What They Were Told: A New Strategy for Improving Access to Kidney Transplantation? 2685 Improving Mutation Screening in Familial Hematuric Nephropathies through Next Generation Sequencing Vincent Morinière, Karin Dahan, Pascale Hilbert, Marieline Lison, Said Lebbah, Alexandra Topa, Christine Bole-Feysot, Solenn Pruvost, Patrick Nitschke, Emmanuelle Plaisier, Bertrand Knebelmann, Marie-Alice Macher, Laure-Hélène Noel, Marie-Claire Gubler, Corinne Antignac, and Laurence Heidet Mark Unruh and Mary Amanda Dew · The Human Response to Acute Enteral and Parenteral Phosphate Loads Roberto Scanni, Matthias vonRotz, Sigrid Jehle, Henry N. Hulter, and Reto Krapf Can Muscle-Kidney Crosstalk Slow Progression of CKD? Helbert Rondon-Berrios, Yanlin Wang, and William E. Mitch 2683 2730 See related article by Salter et al. (pp. 2871–2877). A Nomogram for the Prediction of Kidney Stone Recurrence Brian H. Eisner and David S. Goldfarb · 2689 See related article by Rule et al. (pp. 2878–2886). 2752 Brief Review Regulated Cell Death in AKI Andreas Linkermann, Guochun Chen, Guie Dong, Ulrich Kunzendorf, Stefan Krautwald, and Zheng Dong 2703 Jorge F. Giani, Tea Janjulia, Nikhil Kamat, Dale M. Seth, Wendell-Lamar B. Blackwell, Kandarp H. Shah, Xiao Z. Shen, Sebastien Fuchs, Eric Delpire, Jorge E. Toblli, Kenneth E. Bernstein, Alicia A. McDonough, and Romer A. GonzalezVillalobos Pathophysiology of the Renal Biopsy Renal ApoA-1 Amyloidosis with Glu34Lys Mutation and Intra-amyloid Lipid Accumulation · Nicole K. Andeen, Daniel Y. Lam, Ian H. de Boer, and Roberto F. Nicosia BASIC RESEARCH 2707 Targeted Deletion of p53 in the Proximal Tubule Prevents Ischemic Renal Injury Yuan Ying, Jinu Kim, Sherry N. Westphal, Kelly E. Long, and Babu J. Padanilam Red star . indicates articles that are features in This Month’s Highlights. Renal Angiotensin-Converting Enzyme Is Essential for the Hypertension Induced by Nitric Oxide Synthesis Inhibition 2764 See related editorial by Roksnoer et al. (pp. 2679–2681). Lmx1b and FoxC Combinatorially Regulate Podocin Expression in Podocytes Bing He, Lwaki Ebarasi, Zhe Zhao, Jing Guo, Juha R.M. Ojala, Kjell Hultenby, Sarah De Val, Christer Betsholtz, and Karl Tryggvason 2778 Dynamic O-Linked N-Acetylglucosamine Modiﬁcation of Proteins Affects Stress Responses and Survival of Mesothelial Cells Exposed to Peritoneal Dialysis Fluids Rebecca Herzog, Thorsten O. Bender, Andreas Vychytil, Katarzyna Bialas, Christoph Aufricht, and Klaus Kratochwill P. Kimberly, Barry I. Freedman, Robert R. Graham, and Carl D. Langefeld for the International Consortium for Systemic Lupus Erythematosus Genetics CLINICAL EPIDEMIOLOGY 2871 2789 .Aberrant Glycosylation and Localization of Polycystin-1 Cause Polycystic Kidney in an AQP11 Knockout Model Megan L. Salter, Babak Orandi, Mara A. McAdamsDeMarco, Andrew Law, Lucy A. Meoni, Bernard G. Jaar, Stephen M. Sozio, Wen Hong Linda Kao, Rulan S. Parekh, and Dorry L. Segev Yuichi Inoue, Eisei Sohara, Katsuki Kobayashi, Motoko Chiga, Tatemitsu Rai, Kenichi Ishibashi, Shigeo Horie, Xuefeng Su, Jing Zhou, Sei Sasaki, and Shinichi Uchida 2800 Akt1-Mediated Fast/Glycolytic Skeletal Muscle Growth Attenuates Renal Damage in Experimental Kidney Disease · 2878 2835 2887 Robert A. Fenton, Fiona Murray, Jessica A. Dominguez Rieg, Tong Tang, Moshe Levi, and Timo Rieg 2896 .Sequencing of LRP2 Reveals Multiple Rare Variants Associated with Urinary Trefoil Factor-3 Autophagy Regulates TGF-b Expression and Suppresses Kidney Fibrosis Induced by Unilateral Ureteral Obstruction Gearoid M. McMahon, Matthias Olden, Maija Garnaas, Qiong Yang, Xuan Liu, Shih-Jen Hwang, Martin G. Larson, CKDGen Consortium, Wolfram Goessling, and Caroline S. Fox Lineage Tracing Reveals Distinctive Fates for Mesothelial Cells and Submesothelial Fibroblasts during Peritoneal Injury Yi-Ting Chen, Yu-Ting Chang, Szu-Yu Pan, Yu-Hsiang Chou, Fan-Chi Chang, Pei-Ying Yeh, Yuan-Hung Liu, Wen-Chih Chiang, Yung-Ming Chen, Kwan-Dun Wu, Tun-Jun Tsai, Jeremy S. Dufﬁeld, and Shuei-Liong Lin 2859 An Economic Evaluation of rt-PA Locking Solution in Dialysis Catheters Braden J. Manns, Nairne Scott-Douglas, Marcello Tonelli, Pietro Ravani, Martine LeBlanc, Marc Dorval, Rachel Holden, Louise Moist, Charmaine Lok, Deborah Zimmerman, Flora Au, and Brenda R. Hemmelgarn Renal Phosphate Wasting in the Absence of Adenylyl Cyclase 6 Yan Ding, Sung ll Kim, So-Young Lee, Ja Kun Koo, Zhibo Wang, and Mary E. Choi 2847 See related editorial by Eisner and Goldfarb (pp. 2685–2687). CLINICAL RESEARCH Chia-Hsiang Hsueh, Neal X. Chen, Shien-Fong Lin, Peng-Sheng Chen, Vincent H. Gattone II, Matthew R. Allen, Michael C. Fishbein, and Sharon M. Moe 2822 The ROKS Nomogram for Predicting a Second Symptomatic Stone Episode · See related editorial by Rondon-Berrios et al. (pp. 2681–2683). 2812 .Pathogenesis of Arrhythmias in a Model of CKD See related editorial by Unruh and Dew (pp. 2683–2685). Andrew D. Rule, John C. Lieske, Xujian Li, L. Joseph Melton III, Amy E. Krambeck, and Eric J. Bergstralh Shinsuke Hanatani, Yasuhiro Izumiya, Satoshi Araki, Taku Rokutanda, Yuichi Kimura, Kenneth Walsh, and Hisao Ogawa · Patient- and Provider-Reported Information about Transplantation and Subsequent Waitlisting 2906 .Apolipoprotein B Attenuates AlbuminuriaAssociated Cardiovascular Disease in Prevention of Renal and Vascular Endstage Disease (PREVEND) Participants James P. Corsetti, Ron T. Gansevoort, Stephan J.L. Bakker, Charles E. Sparks, Priya Vart, and Robin P.F. Dullaart 2916 .Improved Glycemic Control and Risk of ESRD in Patients with Type 1 Diabetes and Proteinuria Jan Skupien, James H. Warram, Adam Smiles, Andrzej Galecki, Robert C. Stanton, and Andrzej S. Krolewski Lupus Nephritis Susceptibility Loci in Women with Systemic Lupus Erythematosus Sharon A. Chung, Elizabeth E. Brown, Adrienne H. Williams, PaulaS.Ramos,CelineC.Berthier,TusharBhangale,MartaE. Alarcon-Riquelme, Timothy W. Behrens, Lindsey A. Criswell, DeborahCunninghameGraham,F.YesimDemirci,JeffreyC. Edberg, Patrick M. Gaffney, John B. Harley, Chaim O. Jacob, M. Ilyas Kamboh, Jennifer A. Kelly, Susan Manzi, Kathy L. Moser-Sivils, Laurie P. Russell, Michelle Petri, Betty P. Tsao, Tim J. Vyse, Raphael Zidovetzki, Matthias Kretzler, Robert META-ANALYSIS 2927 Systematic Review and Meta-Analysis on Management of Hemodialysis Catheter-Related Bacteremia Saima Aslam, Florin Vaida, Michele Ritter, and Ravindra L. Mehta 2942 ERRATUM