Anti-Acne Treatment Cream with 2% Salicylic Acid O-0057 Clear pimples and purify your skin with this facial lotion enriched with salicylic acid. Carbopol®* Ultrez 30 polymer offers good viscosity in combination with xanthan gum in the presence of 2% salicylic acid and 5% of an electrolyte-containing extract, at pH 4. Glucamate™* SSE-20 and Glucate™* SS emulsifiers impart good emulsion stabilization. Schercemol™* NGDO ester provides emolliency with high spreadability and light sensory while Glucam™* E-20 humectant imparts humectancy to avoid dryness often associated with salicylic acid. Japanese green tea extract reduces skin irritation imparted by the acidic active. INCI Name, Trade Name A. : 1. Deionized Water 2. Disodium EDTA, Protachem NA2 Weight % 68.35 0.05 Function Diluent Chelating Agent 3. Carbomer, Carbopol®* Ultrez 30 Polymer 1.00 Rheology Modifier 4. Glycerin, Glycerin, 99.7% USP 2.00 Humectant 5. Xanthan Gum, Keltrol® CG 0.25 Thickener 6. Methyl Gluceth-20, Glucam™* E-20 Humectant 1.00 Humectant 7. Neopentyl Glycol Diethylhexanoate, Schercemol™* NGDO Ester 5.00 Emollient 8. PEG-20 Methyl Glucose Sesquistearate, Glucamate™* SSE-20 Emulsifier 0.60 Emulsifier 9. Methyl Glucose Sesquistearate, Glucate™* SS Emulsifier 0.30 Emulsifier 10. Cetearyl Alcohol, Protachem CS-50 1.00 Structurant 11. Tocopheryl Acetate, Vitamin E Acetate USP 0.25 Antioxidant D. 12. Sodium Hydroxide (18% Solution) 2.70 Neutralizer E. 13. Butylene Glycol 6.00 Solubilizer 14. Alcohol, Ethyl Alcohol 4.00 Solubilizer 15. Salicylic Acid 2.00 Anti-Acne 16. Water, Glycerin, Camellia Oleifera Leaf Extract, Actiphyte® of Japanese Green Tea GL 5.00 Anti-irritant 17. Phenoxyethanol (and) Ethylhexylglycerin, Euxyl® PE 9010 0.50 Preservative B. C. F. Product Properties: Appearance Off-white lotion pH 4.0 – 4.5 Viscosity (mPa·s)** 7,000 – 11,000 Yield Value (dyn/cm²) 650 – 900 Stability: Passed 2 months at RT, 45°C and 50°C. Passed 4 F/T cycles. Recommended Packaging: PVC round cylinder, white 1 oz. Pump: smooth, clear, 200 mcl, 20/410 white. **Brookfield RV, DVII+ Viscometer spindle #5 @ 20 rpm, RT @ 24 hours Supplier References: Protameen (2, 10) Lubrizol Advanced Materials, Inc. (3, 6, 7, 8, 9) CP Kelco (5) Essential Ingredients (11) Active Organics (16) Schülke & Mayr (17) O-0057 Edition: April 25, 2013 Reference #: 1018P-013 (CSIM) Original Edition: March 19, 2013 - Continued Next Page - Lubrizol Advanced Materials, Inc. / 9911 Brecksville Road, Cleveland, Ohio 44141-3247 / TEL: 800.379.5389 or 216.447.5000 The information contained herein is being furnished for informational purposes only, upon the express condition that the User makes its own assessment of the appropriate use of such information. While the information contained herein is believed to be reliable, no representations, guarantees or warranties of any kind are made as to its accuracy, suitability for a particular application or the results to be obtained herefrom. Lubrizol Advanced Materials, Inc. ("Lubrizol") cannot guarantee how any products associated with this information will perform in combination with other substances or in User’s process. Due to the variations in methods, conditions and equipment used commercially in processing these materials, no warranties or guarantees are made as to the suitability of the information/products for the applications disclosed. Lubrizol shall not be liable and the User assumes all risk and responsibility for, any use or handling of any material beyond Lubrizol's direct control. LUBRIZOL MAKES NO WARRANTIES, EXPRESS OR IMPLIED, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY OR FITNESS FOR A PARTICULAR PURPOSE. It is the User’s sole responsibility to determine if there are any issues relating to patent infringement of any component or combination of components relating to the supplied information. Nothing contained herein is to be considered as permission, recommendation, nor as an inducement to practice any patented invention without the permission of the patent owner. For further information, please visit: www.lubrizol.com/personalcare Lubrizol Advanced Materials, Inc. is a wholly owned subsidiary of The Lubrizol Corporation *Trademark owned by The Lubrizol Corporation © Copyright 2013 / The Lubrizol Corporation Anti-Acne Treatment Cream with 2% Salicylic Acid Procedure: 1. Combine PART E ingredients and mix until Salicylic Acid Crystals are fully dissolved. Set aside for later addition. 2. PART A: Dissolve Disodium EDTA in water. When Disodium EDTA is fully dissolved, set mixing speed @ 400-500 rpm and slowly disperse Carbopol®* Ultrez 30 polymer in water. Continue mixing until polymer is fully hydrated. 3. Add PART B ingredients to PART A. Mix until uniform. Begin heating to 60-65°C. 4. Combine PART C ingredients and heat to 60-65°C. Mix until uniform and add to PART A/B. Continue mixing until uniform. 5. When batch is uniform, remove from heat and add PART D. Increase mixing as needed to maintain a good vortex. 6. Continue mixing through cool down. When batch is near or at room temperature, add PART E to batch. Adjust mixing speed as needed to reduce splashing along sides of vessel. 7. Add PART F ingredients individually with good mixing between additions. 8. Q.S. any water loss during heating. O-0057