OPDC Programme - Oxford Parkinson`s Disease Centre
OPDC Programme 0830 Registration 0900 Welcome and Introduction Dr Richard Wade-Martins · Oxford Parkinson’s Disease Centre 0910 Special Guest Dr Arthur Roach · Director of Research and Development at Parkinson's UK 0920 Special Guest Paul Mayhew Archer · Parkinson's UK, Oxford Progress in Parkinson’s Clinical Research Chair: Professor Paul Matthews and Professor Howard Federoff 0930 The Oxford Parkinson’s Disease Centre (OPDC) Clinical Cohort Dr Michele Hu · Oxford Parkinson’s Disease Centre · Nuffield Department of Clinical Neurosciences 0950 Parkinson’s and REM sleep behaviour disorder Dr Michal Rolinski · Oxford Parkinson’s Disease Centre · Nuffield Department of Clinical Neurosciences 1010 SELECTED ABSTRACT A general copper-mediated nucleophilic 18F fluorination of arenes: application to 6-[18F]fluoro-L-DOPA Dr Enrico Emer and Professor Véronique Gouverneur · Chemistry Research Laboratory 1025 Coffee and Posters Proteomics and Neuropathology in Parkinson’s Chair: Professor Jeffrey Kordower and Professor Patrik Brundin 1055 Developing Parkinson's proteomic biomarkers: lessons from studies in Alzheimer's 1115 Molecular mechanisms of endosomal trafficking and their translational application in Parkinson's disease Professor Simon Lovestone · Oxford Parkinson’s Disease Centre · Department of Physichiatry Dr George Tofaris · Oxford Parkinson’s Disease Centre · Nuffield Department of Clinical Neurosciences 1135 Selective vulnerability and prion-like propagation in Parkinson’s disease Dr Laura Parkkinen · Oxford Parkinson’s Disease Centre · Nuffield Department of Clinical Neurosciences 1155 KEYNOTE LECTURE · Cohort studies in Parkinson’s disease: Tracking Parkinson’s Dr Donald Grosset Institute of Neurological Sciences, Glasgow; University of Glasgow 1225 Lunch and Posters Investigating the Cellular and Molecular Biology of Parkinson’s Chair: Professor Clive Svendsen 1325 Omics and the OPDC: Network approaches to Parkinson’s Dr Caleb Webber · Oxford Parkinson’s Disease Centre · MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics 1345 Generating iPS cells from the OPDC cohort, and their use for disease modelling Dr Sally Cowley · Oxford Parkinson’s Disease Centre · Sir William Dunn School of Pathology 1405 Translating Parkinson's: stem cell-derived patient neurons for target discovery Dr Richard Wade-Martins · Oxford Parkinson’s Disease Centre · Department of Pysiology, Anatomy & Genetics 1425 KEYNOTE LECTURE· Parkinson’s disease; considerations from a simple (organism) perspective Dr Alex Whitworth Reader in Neurogenetics, Department of Biomedical Science, The University of Sheffield 1455 Tea and Posters Molecules to Movement: Improved Animal Models of Parkinson’s Chair: Professor Marie-Francoise Chesselet 1525 BAC transgenic rodent models of Parkinson’s disease 1545 SELECTED ABSTRACT Bioenergetic and autophagic impairments drive age-dependent Dr Natalie Connor-Robson · Oxford Parkinson’s Disease Centre · Department of Physiology, Anatomy & Genetics neurodegeneration in an α-synuclein overexpression BAC-transgenic mouse model Dr Brent Ryan · Oxford Parkinson’s Disease Centre · Department of Physiology, Anatomy & Genetics 1600 Intersectional optogenetic tools to explore dopamine neuron heterogeneity in Parkinson’s disease Dr Sarah Threlfell · Oxford Parkinson’s Disease Centre · Department of Physiology, Anatomy & Genetics 1620 Altered encoding of movement by dopamine neurons in early Parkinson’s 1640 KEYNOTE LECTURE· Functional changes of dopamine substantia nigra Dr Paul Dodson · Oxford Parkinson’s Disease Centre · MRC Anatomical Neuropharmacology Unit neurons in Parkinson Disease Professor Jochen Roeper Neuroscience Centre, Institute for Neurophysiology, Goethe University, Frankfurt 1710 Concluding Remarks from Special Guest Sally Bromley · Chair, Oxford Branch Parkinson’s UK · Monument Discovery Cohort Participant 1720 Poster Prize Award 1725 Drinks and Posters 1900 Research Day ends
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