www.palsgi.com PENNSYLVANIA Life Sciences Greenhouse Initiative April 2015 Regionally Attuned Capital Efficient Sector-Specific Expertise Imp r o v i ng H u m an H e al t h an d th e C ommon wealth ’s E conom y The Life Sciences Greenhouses are models of effectiveness and efficiency. They capture the innovation potential of the life sciences industry and nurture that potential with critical early-stage funding and sector-specific business expertise. Pennsylvanians benefit directly as new companies are formed, jobs are created, additional capital is attracted to the Commonwealth, and life-saving technologies reach patients. 215.966.6214 I bioadvance.com Results New Companies • 211 companies and projects funded • 21 companies have exited, providing returns to investors and entrepreneurs 717.635.2100 I lsgpa.com Additional Capital • More than $3.2 billion in private follow-on funding • $105.1 million in follow-on federal funding More Jobs • 4,279 jobs created 412.201.7370 I plsg.com • The average life sciences salary is $90,267, twice the average PA private sector wage 175 Life-Saving Technologies • 46 products originated by LSG companies have received regulatory approval • 149 new, unregulated products are being commercialized See examples of breakthrough products on reverse. Private-sector leverage of state dollars: 43:1 Healthcare Breakthroughs April 2015 from Pennsylvania Life Sciences Greenhouse Initiative Portfolio Companies The table below highlights just a few of the breakthrough products brought to market by companies backed by the Life Sciences Greenhouse Initiative. Company ALung Product name Use Hemolung® RAS Respiratory assist system Regulatory approval LSG investor EU PLSG Avid/Lilly Amyvid™ Determines presence of beta amyloid plaque in patients with cognitive impairment FDA BA Ceptaris VALCHLOR™ (mechlorethamine) gel Determines presence of beta and IB mycosis fungoides-type cutaneous T-cell lymphoma (CTCL) FDA BA Cohera Medical Safe tissue adhesives EU PLSG TissuGlu® Surgical Adhesive Sylys® Surgical Sealant Health Monitoring EpiCenter™ Systems EpiStart MediCenter Monitor disease outbreak Not applicable PLSG Indigo BioSciences Receptor, Receptor Assay Kits (38 total) R&D kits Not Applicable LSGPA InfraScan InfraScanner 1000 InfraScanner 2000 Hand held device to detect brain hematoma after head trauma FDA BA INRange Systems EMMA® Remote medication management FDA LSGPA Maculogix AdaptDx™ Study of visual function and ocular disease FDA LSGPA NuPathe Zecuity® Sumatriptan transdermal patch or migraine FDA BA Novasentis Clic-10™ Haptic feedback Not applicable LSGPA Rinovum Women’s Health Stork™ Rinovum Vitamin Line Reproductive health aid FDA PLSG Saladax Biomedical MyCare™ Chemotherapy optimization Not applicable LSGPA BA = BioAdvance – Biotechnology Greenhouse of Southeastern Pennsylvania 215.966.6214 I bioadvance.com LSGPA = Life Sciences Greenhouse of Central Pennsylvania 717.635.2100 I lsgpa.com PLSG = Pittsburgh Life Sciences Greenhouse 412.201.7370 I plsg.com