LUCA POLLONINI University of Houston Department of Engineering Technology and Abramson Center for the Future of Health 300 Technology Building Houston, TX 77204‐4021 Tel: (713) 743‐4159 E‐mail: [email protected] Web: polloninilab.com EDUCATION Ph.D., Information Engineering University of Brescia, Italy ― March 2004 Thesis: Design and development of an optical system for early diagnosis of ocular pathologies Master of Science, Electrical Engineering University of Brescia, Italy ― October 2000 Thesis: In‐vivo characterization of ocular tissues by signal analysis of autofluorescence and dynamic light scattering RESEARCH APPOINTMENTS Research Assistant Professor University of Houston, TX ― September 2010 – present Postdoctoral Fellow University of Houston, TX ― September 2008 – August 2010 Postdoctoral Fellow University of Texas Health Science Center, Houston, TX ― October 2007 – August 2008 Research Associate NASA Glenn Research Center, Cleveland, OH ― November 2003 – November 2004 PROFESSIONAL EMPLOYMENT Co‐Founder and Chief Technology Officer Nirox LLC, Brescia, Italy ― December 2004 – September 2007 AFFILIATIONS Assistant Affiliate Member Houston Methodist Research Institute ― April 2014 – present Luca Pollonini, Ph.D. 3 PUBLICATIONS Journal articles L. Pollonini, N. Padhye, R. Re, P. Howell, R.J. Simpson and C.C. Dacso, “Pulse transit time measured by photoplethysmography improves the accuracy of heart rate as a surrogate measure of cardiac output, stroke volume and oxygen uptake in response to graded exercise”, Physiol Meas 2015 Jan 9 [Epub ahead of print] L. Pollonini, C. Olds, H. Abaya, H. Bortfeld, M.S. Beauchamp, J.S. Oghalai, "Auditory cortex activation to natural speech and simulated cochlear implant speech measured with functional near‐infrared spectroscopy", Hear Res 2014 Mar; 309:84‐93 J. León‐Carrión, U. León‐Domínguez, J. Halper, L. Pollonini, G. Zouridakis, M.R. Domínguez‐Morales, “Restoring Cortical Connectivity Directionality and Synchronization is Essential to Treating Disorder of Consciousness”, Curr Pharm Des. 2013 Sep 10. [Epub ahead of print] J. Leon‐Carrion, U. Leon‐Dominguez, L. Pollonini, Meng‐Hung Wu, R.E. Frye, M.R. Dominguez‐Morales, G. Zouridakis, “Synchronization between the anterior and posterior cortex determines consciousness level in patients with traumatic brain injury (TBI)”, Brain Res 1476 (2012): 22‐30 L. Pollonini, N. O. Rajan, S. Xu, S, Madala and C.C. Dacso, "A Novel Handheld Device for Use in Remote Patient Monitoring of Heart Failure Patients—Design and Preliminary Validation on Healthy Subjects", J Med Syst 2012, 36: 653‐659 L. Pollonini, S. Pophale, N. Situ, M.H. Wu, R.E. Frye, J. Leon‐Carrion and G. Zouridakis, "Information Communication Networks in Severe Traumatic Brain Injury", Brain Topogr Vol. 23 (2), 2010 L. Rovati, A. Bandera, M. Donini, G. Salvatori and L. Pollonini, “Design and performance of a wide‐
bandwidth and sensitive instrument for near‐infrared spectroscopic measurements on human tissue”, Rev Sci Instrum, Vol. 75(12), pp. 5315‐5325, 2004 L. Rovati, L. Pollonini and F. Docchio "A system for the inspection and quality control of glass slabs", Rev Sci Instrum, Vol. 73(9), pp. 3386‐3391, 2002 Conference Proceedings S. Jain, Q. Feng, J.V. Kovach and L. Pollonini,” An Integrated Assessment for Optimizing Cardiopulmonary Rehabilitation”, ISERC 2015, Nashville, TN – May 30 – Jun 2, 2015 L. Pollonini, C. Olds, H. Abaya, H. Bortfeld, M.S. Beauchamp and J.S. Oghalai, “Real‐time mapping of optode‐scalp optical coupling for optimized placement of fNIRS headgear”, Society for the Functional Near‐Infrared Spectroscopy, Montreal, Canada – Oct 10‐12, 2014 J. Chen, S. Quadri, L. Pollonini, S. Naribole, J. Ding, Z. Zheng, E.W. Knightly, C.C. Dacso, “Blue Scale: Early Detection of Impending Congestive Heart Failure Events via Wireless Daily Self‐Monitoring”, IEEE Healthcare Innovation and Point of Care Conference, Seattle, WA – Oct 8‐10, 2014 Luca Pollonini, Ph.D. 4 L. Pollonini, S. Quadri, J. Chen, J. Ding, Z. Zheng, S. Naribole, K.K. McArthur, E.W. Knightly and C.C. Dacso, “Blue Scale: a multi‐sensing device for remote management of congestive heart failure”, Annual Conference of IEEE Engineering in Medicine and Biology Society, Chicago, IL – August 26th‐30th, 2014 C.C. Dacso, L. Pollonini, and A. Amodeo,” Integrated device for the post‐operative monitoring of cardiac functions in pediatric populations”, Annual Conference of IEEE Engineering in Medicine and Biology Society, Osaka, Japan – July 3rd‐7th, 2013 C. Olds, L. Pollonini, H. Abaya, R. Gurgel, M.S. Beauchamp, H. Bortfeld, J.S. Oghalai, “Cortical Hemodynamic Response to Speech Stimuli in Adult Cochlear Implant Users by Functional Near‐Infrared Spectroscopy”, Annual Meeting of the Association for the Research in Otolaringology, Baltimore, MD, February 16‐20, 2013 L. Pollonini, R. Re, R.J. Simpson and C.C. Dacso, “Integrated device for the measurement of systemic and local oxygen transport during physical exercise”, Annual Conference of IEEE Engineering in Medicine and Biology Society, San Diego, CA – August 28th‐September 1st, 2012 L. Pollonini, R. Re, P. Howell, K. Prasad, R. Simpson and C. Dacso, “Relationship between systemic and local physiological response to graded exercise assessed with near‐infrared spectroscopy”, Med. Sci. Sports Exerc. 2012, Vol. 44:5 ‐ Annual Meeting of the American College of Sports Medicine, San Francisco, CA – May 29th ‐ June 2nd, 2012 L. Pollonini, C.C. Dacso, “Wearable sensing device for home monitoring of cardiac rehabilitation”, AMA‐
IEEE Medical Technology Conference – October 16th‐18th, 2011 ‐ Boston, USA N.O. Rajan, L. Pollonini, Amy M. Harris, L. Reichlin, S. Xu, K. McArthur, C.M. Queen, C.C. Dacso, “Novel in‐home monitoring device for patients suffering from congestive heart failure”, Proceedings of the 138th APHA Annual Meeting, Denver, CO, November 6‐10, 2010 L. Pollonini, U. Patidar, N. Situ, R. Rezaie, A.C. Papanicolaou, and G. Zouridakis, " Functional Connectivity Networks in the Autistic and Healthy Brain Assessed using Granger Causality", IEEE Engineering in Medicine and Biology Society conference 2010, August 31‐September 4, Buenos Aires, Argentina (Invited) G. Zouridakis, U. Patidar, N.S. Padhye, L. Pollonini, A. Passaro and A.C. Papanicolaou, “Spectral Power of Brain Activity Associated with Emotion — A Pilot MEG Study”, IFMBE Proceedings, 17th International Conference on Biomagnetism Advances in Biomagnetism – Biomag 2010, March 28 – April 1, 2010 Dubrovnik, Croatia L. Pollonini, M. Rodriguez, R. Opperman, J. Waldie, J. Hochstein, J. A. Jones and R. R. Ansari, “A Fiber‐
Optic Laser Doppler Sensor for the Monitoring of Fingertip Blood Flow in Astronauts”, Houston Conference on Biomedical Engineering Research, Houston, TX, March 19‐20, 2009 R. Opperman, J. Waldie, J. Hochstein, A. Natapoff, L. Pollonini, R. Ansari, J. Jones, D.J. Newman, "Anthropometric and Blood Flow Characteristics Leading to EVA Hand Injury", International Conference on Environmental Systems (ICES), 2009‐01‐2471, Savannah, GA, July 2009 Luca Pollonini, Ph.D. 5 L. Pollonini, S. Pophale, N. Situ, J. Leon‐Carrion and G. Zouridakis, “EEG Network Connectivity Analysis in Traumatic Brain Injury Patients”, Houston Conference on Biomedical Engineering Research, Houston, TX, March 19‐20, 2009 R. Ansari, J. Jones, L. Pollonini, M. Rodriguez, R. Opperman, J. Hochstein, " A Noninvasive Miniaturized‐
Wireless Laser‐Doppler Fiber‐Optic Sensor for Understanding Distal Fingertip Injuries in Astronauts ", SPIE Proc. Vol. 7186, 2009 (SPIE 2009, San Jose (CA, USA), January 26, 2009) L. Rovati, L. Pollonini, R.R. Ansari, “Design and Performance of an Ophthalmic Instrument for Dynamic Light Scattering and Fluorescence Measurements in Ocular Tissues”, IEEE/IMTC Proc., pp. 1975‐1979, 2004 L. Pollonini, R.R. Ansari, A. Pasquali, L. Rovati, L. Quaranta, “Non invasive evaluation of pigment dispersion syndrome using dynamic light scattering”, ARVO Proc., Invest. Ophth. & Vis. Sci., pp. 959/B932, 2004 (ARVO 2004, Fort Lauderdale (FL, USA), 2‐5 May 2004) L. Rovati, L. Pollonini, M. Zanasi, D. Sivieri, M. Badiali, ”Design of an optical sensor for surface roughness measurements of wood based panels”, Sensors for Industry Conference 04, Proceedings the ISA/IEEE , pp. 55 – 59, 2004 L. Pollonini, R.R. Ansari and L. Rovati, “Simulation of optical path and volume‐under‐test calculation in an integrated dynamic light scattering and autofluorescence device”, SPIE Proc. Vol. 5314, pp.71‐78, 2004 (SPIE 2004, San Jose (CA, USA), January 17‐23, 2004) L. Rovati, A. Bandera, M. Donini, L. Pollonini, “A novel tissue oxymeter combining the multidistance approach with an accurate spectral analysis”, IEEE/IMTC Proc., Vol. 1, pp.214‐217, 2003 (IMTC 2003 – Instrumentation and measurements technology conference, Vail, CO, USA, 20‐22 May 2003) L. Pollonini, L. Rovati, A. Pasquali, A. Franzoni, L. Quaranta, "Pigment dispersion syndrome assessment with a novel dynamic light scattering system", SPIE Proc., Vol. 4951, pp.161‐167, 2003 (SPIE 2003, San Jose (CA, USA), January 25‐31, 2003) L. Pollonini, L. Rovati, R.R. Ansari, "Dynamic light scattering and autofluorescence of healthy and pathological ocular tissues", SPIE Proc. Vol. 4611, pp.213‐219, 2002 (SPIE BiOS 2002, January 19‐26, 2002, San Jose, CA, USA) L. Pollonini, A. Pasquali, L. Rovati, R.R. Ansari, "A microcontroller‐based front‐end electronics for simultaneous measurements of dynamic light scattering and natural fluorescence", SPIE Proc. Vol. 4611, pp.205‐212, 2002 (SPIE BiOS 2002, January 19‐26, 2002, San Jose, CA, USA) L. Pollonini, L. Rovati and R.R. Ansari "Dynamic light scattering and natural fluorescence measurements of the corneal tissue", SPIE Proc., Vol. 4434, pp.263‐267, 2001 (European Conference on Biomedical Optics (ECBO), Munich, German, June 17‐21, 2001) L. Rovati, L. Pollonini and R.R. Ansari, "Integrated instrument for dynamic light scattering and natural fluorescence measurements", SPIE Proc., Vol. 4245, pp.192‐198, 2001 (SPIE BiOS 2001, Ophtalmic Technologies XI, January 20‐26, San Jose, CA, USA) Luca Pollonini, Ph.D. 6 Manuscripts currently under review or in preparation for submission C. Olds, L. Pollonini, H. Abaya, H. Bortfeld, M.S. Beauchamp and J.S. Oghalai, “Cortical activation patterns linked to speech understanding after cochlear implantation”, under review at the Journal of the Association for Research in Otolaryngology L. Pollonini, C. Olds, H. Abaya, H. Bortfeld, M.S. Beauchamp and J.S. Oghalai, “PHOEBE: a quantitative method for real‐time mapping of optode‐scalp coupling in functional near‐infrared spectroscopy”, to be submitted to Journal of Neuroscience Methods L. Pollonini, B. Heaps, R. Re, A. Torricelli, T. Dupler, R.J. Simpson and C.C. Dacso, “Non‐invasive estimation of anaerobic threshold by muscle oxygenation measured with near infrared spectroscopy in response to graded exercise”, to be submitted to European Journal of Applied Physiology L. Pollonini, R. Goel, W.H. Paloski, and R.J. Simpson, “Real‐time algorithms for measurement of ventilatory threshold during sub‐maximal exercise testing”, to be submitted to Journal of Applied Physiology L. Pollonini, S.E. Parazynski and J. Friedman, “Detection of vascular occlusions during free flap transplantation by near‐infrared spectroscopy imaging”, to be submitted to Applied Optics PATENTS L. Pollonini, C.C. Dacso, "Apparatus and Method for Improving Training Threshold”, Issued Patent US20130096403 A1 – PCT/US2012/060100 L. Pollonini, S. Parazynski, “Imaging system for intra‐ and post‐operative blood perfusion monitoring” – Patent Application US2014/537,509 – PCT/US14/64844 L. Pollonini, C.C. Dacso, “Methods for measuring physiological parameters of physical activity” – Patent Application U.S. 61/955,442 L. Pollonini, R.J. Simpson, W. Paloski, “Systems and Methods for Real‐Time Detection of Ventilatory Threshold Using Respiratory Gas Analysis” – Patent Application U.S. 62/045,335 GRANTS AND SPONSORED RESEARCH AWARDS Institute for Collaboration in Health Sponsored Research Award, 2014 ― “Measurement and monitoring of tissue oxygenation for detection of hypoxic events during surgery and long‐term hospitalization”, Total award $30,000 Houston Methodist Hospital Research Institute Sponsored Research Award, 2013 ― “Design and development of an imaging system for intra‐ and post‐operative blood perfusion monitoring”, Principal Investigator, 100% effort – Total award $20,000 Luca Pollonini, Ph.D. 7 Finger Fellowship Sponsored Research Mentorship, 2012‐2014 ― “Wearable optical device for in‐vivo assessment of tissue oxygenation by near‐infrared spectroscopy” ― Mentored 4 graduate students, each earning a $5,000 stipend National Science Foundation CNS‐1117560, 2011‐2014 ― “NeTS: Small: Toward wireless co‐existence for safety‐critical applications”, Co‐Investigator, 11% effort, Total award $300,000 National Institutes of Health R56 DC010164‐01A1, 2010‐2012 ― “Translation of near‐infrared Spectroscopy for use in clinical neuro‐imaging”, Sub‐award from Stanford University, CA – Principal Investigator, 100% effort – UH award $62,830 – Total award $412,000 Gillson‐Longenbaugh Foundation Sponsored Research Award, 2010‐date ― “Metabolic Syndrome Blue Box project”, Total award $85,000 Private donors Sponsored Research Award, 2010 ― “Near‐Infrared Spectroscopy coupled to noninvasive cardiac assessment for improving training threshold”, Total award $50,000 AWARDS AND HONORS University of Houston―Wolﬀ Center for Entrepreneurship Most innovative research‐driven patent, 2014 ― “Clinical Monitoring of Blood‐flow in Skin‐Flaps” Association for Research in Vision and Ophthalmology Best poster and travel grant, 2004 ― “Non‐invasive evaluation of pigment dispersion syndrome using dynamic light scattering” Lombardy Institute ‐ Academy of Science and Literature (Milan, Italy) Best science thesis of the year, 2001 ― ”In‐vivo characterization of ocular tissues by signal analysis of autofluorescence and dynamic light scattering” TEACHING University of Houston ELET 2300―Introduction to C++ programming, 2008―2011, 2014―date ELET 1401, Electric Circuits and laboratory II, 2015―date EDITORIAL SERVICE Associate Editor IEEE Journal of Translational Engineering in Health and Medicine Luca Pollonini, Ph.D. 8 Journal Referee Applied Clinical Informatics Applied Optics Biomedical Optics Express Hearing Research IEEE Journal of Translational Engineering in Health and Medicine IEEE Transactions on Biomedical Engineering Journal of Biomedical Optics Journal of the Optical Society of America A Journal of Medical Systems Journal of Speech, Language, and Hearing Research Optics Express Optics Letters PLOS One Psychophysiology Review of Scientific Instruments Technical Committees IEEE Engineering in Medicine and Biology Conference (EMBC), 2011―date IEEE International Conference on Computer‐Based Medical Systems (CBMS), 2014―date IEEE International EMBS Neural Engineering Conference (NER), 2013―date SERVICE TO THE PROFESSION Panelist, National Science Foundation, 2013―date DEPARTMENTAL/UNIVERSITY SERVICE Intellectual Property Committee, University of Houston, 2013―date PROFESSIONAL MEMBERSHIPS Ins tute of Electrical and Electronics Engineers, Member, 2011―date Luca Pollonini, Ph.D. 9