ECMO ELSA Monitor ® Extracorporeal Life Support Assurance Monitor The new Transonic ELSA® (Extracorporeal Life Support Assurance) Monitor measures Oxygenator Blood Volume, Delivered Blood Flow and Recirculation during veno-venous extracorporeal membrane oxygenation (VV ECMO). ELSA® measurements confirm that the ECMO circuit is functioning as intended. They are used to guide the positioning of the dual lumen catheter in order to optimally balance Flow with Recirculation so that the patient receives the oxygenation necessary to maintain life and promote recovery. ELSA Cover sheet (ELS-200-fly) RevA 2013 ECMO When critically ill patients’ lives rest on accurate assessments of their conditions and their individual responses to treatment, the new Transonic bedside ELSA® (Extracorporeal Life Support Assurance) ICU Monitor provides intensivists with rapid quantitative data throughout the course of life support. This timely data assists the clinician in guiding interventions to minimize recirculation and fully optimize the oxygenation therapy.1 To generate ELSA® measurements, flow dilution sensors are simply clipped onto the supply and return lines of a VV ECMO circuit. Once the software program is opened on the ELSA Monitor, on-screen instructions are displayed. Actual delivered blood flow measurements are immediately available. A small saline bolus is used to calculate either percent recirculation or oxygenator blood volume. Percent recirculation provides the physician with real-time information about the patient’s response to treatment. Oxygenator blood volume insures adequate anticoagulation to maintain oxygenator functionality. Fig. 1: ELSA Monitor screen displaying indicator dilution curve that registers 0% Recirculation. References: [1] Clements D et al,“Measurements of recirculation during neonatal veno-venous extracorporeal membrane oxygenation: clinical application of the ultrasound dilution technique”. J Extra Corpor Technol 2008 Sep;40(3):184-7 (Transonic Reference # ELS9680AH) [2] van Heijst AF et al, “Recirculation in double lumen catheter veno-venous extracorporeal Fig. 2: ELSA Monitor screen displaying indicator dilution curve that registers small (11%) Recirculation. membrane oxygenation measured by an ultrasound dilution technique”. ASAIO J. 2001;47(4):372-6. (Transonic Reference # ELS9766AH) [3] Körver EP e al, “Quantification of recirculation as an adjuvant to transthoracic echocardiography for optimization of dual-lumen extracorporeal life support”. Intensive Care Med 2012;38(5):906-9. (Transonic Reference # ELS9679AH) [4] Darling EM et al, “Use of dilutional ultrasound monitoring to detect changes in recirculation during venovenous extracorporeal membrane oxygenation in swine”. ASAIO J 2006;52(5):522-4. (Transonic Reference # ELS7309V) [5] Walker J et al, “The potential of accurate SvO2 monitoring during venovenous extracorporeal membrane oxygenation: an in vitro model using ultrasound dilution”. Perfusion 2007;22(4):239-44. (Transonic Reference # ELS7584A) [6] Melchior R et al, “A novel method of measuring cardiac output in infants following extracorporeal procedures: preliminary validation in a swine model”. Perfusion 2005;20(6):323-7. (Transonic Reference # ELS7177V) Fig. 3: ELSA Monitor screen that displays indicator dilution curve that registers large (45%) Recirculation. Transonic Systems Inc., global manufacturer of biomedical flow measurement equipment, sells “gold standard” ultrasound transit-time flowmeters, hemodialysis, endovascular and laser Doppler perfusion monitors worldwide to surgeons, nephrologists, interventional radiologists, researchers and original equipment manufacturers (OEMs). www.transonic.com AMERICAS EUROPE ASIA/PACIFIC JAPAN Transonic Systems Inc. 34 Dutch Mill Rd. Ithaca, NY 14850 U.S.A. Tel: +1 607-257-5300 Fax: +1 607-257-7256 [email protected] Transonic Europe B.V. Business Park Stein 205 6181 MB Elsloo The Netherlands Tel: +31 43-407-7200 Fax: +31 43-407-7201 [email protected] Transonic Asia Inc. 6F-3 No 5 Hangsiang Rd Dayuan, Taoyuan County 33747 Taiwan, R.O.C. Tel: +886 3399-5806 Fax: +886 3399-5805 [email protected] Transonic Japan Inc. KS BLdg 201,735-4 Kita-Akitsu Tokorozawa SAITAMA 359-0038 Japan Tel: +81 04-2946-8541 Fax: +81 04-2946-8542 [email protected]
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