Desogestrel mini pill: Is this safe in lactating mother-A prospective study Dr.DiliP Kumar Dutta M.D ,Ph.D, F.I.C.O.G,F.I.C.M.C.H M.A.M.S ,D.A.C.O.G( USA) D.P.S(GERMANY) Introduction: • Lactating mother at postnatal clinic, often asked for safe and effective contraceptive to prevent further pregnancy during lactating period. • As per the multicenter study, desogestrel (75ug/day) as compared to other contraceptive, is now safely used in a women in whom an oestrogen-containing contraceptive is either contra-indicated, or may cause side effects or health concern for both mother and breastfeed baby. Materials and Methods • The prospective clinical study was carried out on 200 lactating mother during the period from January 2010 to 30st June 2011 at Gice Clinic, Kalyani, Nadia W.B. In this studies 200 cases were taken as placebo for comparison. • For this studies- desogestrel-only pill (75ug/day) was started after 6 weeks of delivery for 6 months period. • The main objective of this study was:– – – – • To find out any alternation of quality and composition of breast milk To observe any failure of contraception To check the tolerability or side effects To assess any effect on growth and development of the breast baby. During the period of study patient were reviewed At 8th, 12th, 16th, 24th, week and up to 1 year. Exclusion criteria • Family history or past history of thrombo-embolism are excluded from this study. Results Table-I - Study of any alternation of amount and composition of breast milk in both group Table-II To study the tolerability, side effects and Menstruation in both group Table III Study on effect of changes lipid and carbohydrate metabolism and thyroid function in both group Table-IV Study of contraceptive effectiveness on pregnancy in both group Table V Study of effect of growth and development of breast feed baby in both group Conclusion • Safe,accepted by majority of lactating mother • Good tolerability,less side effect • Good contraceptive efficacy • No effect on growth and development of breast feed baby. Thank you