CONFERENCE PROGRAM Monday, March 16 Welcome and registration: 12:30-14:00 Updates on first responders’ needs, responses to current CBRN crisis, R&I projects (Amphitheater): 14:00-19:40 Chairs: Y. Morel, F. Thibault, D. Josse, L. Olmedo 14:0014:20 14:2014:40 14:4015:00 15:0015:20 15:2015:40 15:4016:00 16:0016:20 16:2016:40 16:4017:20 17:2017:40 17:4018:00 18:0018:20 18:2018:40 INTRO-01 Introduction INTRO-02 V. Goury INTRO-03 M. Bosco "Which European research for the coming years and for which CBRN-E users?" INTRO-04 F. Murgadella and L. Lachenaud “The French CBRNE research and innovation strategy” INTRO-05 G. Winfield “Generic Integrated Forensic Toolbox for CBRN incident – GIFT” COFFEE BREAK INTRO-06 E. Pautasso “A pilot project to strengthen the cooperation between first responders and law enforcement agents in responding to CBRN events: outcomes and opportunities of collaboration” INTRO-07 R.Orford “European Chemical Emergency Network (ECHEMNET) – Preparing, assessing and responding to cross border chemical health threats” INTRO-08 H. Maibach "Water decontamination: to be or not be" BREAK INTRO-09 C. Bossuet “French trans-governmental CBRN-E R&D program” INTRO-10 Colonel V. Pech de Laclause “The French Military CBRN Defence : principles and issues” INTRO-11 A. Gauci “Roadmaps: how do we create the link between the need and the product, between the lab and real-life equipment” CONFERENCE PROGRAM Monday, March 16 18:4019:00 19:0019:20 INTRO-12 Lieutenant-Colonel F. Jean “The French Civilian Security: current approach and future developments to face CBRN risks” INTRO-14 S. Pereira Rodrigues " Experts on the field to pilot a mobile laboratory: a fast and accurate answer to assessment of the CBRN threats" Cheese and Wine (Exhibition Hall): 19:40-21:30 Suppliers and first responders show room (Exhibition Hall): 19:40-21:45 Alpes-Maritimes FRS (SDIS06), BMPM, Cristanini, GIE NBC Defense (Bertin Technologies, CEA, IMS, Paul Boyé Technologies, Serb Laboratories), NBC-Sys, Ouvry, Rekah, Securetec, 4S-security, Tradeways. Animated by the French Innovative Cluster for Risk Management (Pole Risques) (J-M. Dumaz) 19h4520:00 20:0020:15 20:1520:30 20:3020:45 20:4521:00 21:0021:15 SHOW-01 E. Daguerre (Paul Boyé Technologies) "Advanced low burden Chemical and Biological protective garment" SHOW-02 M. Jacoby (Cristanini) “CBRN Multirole Decontamination Products and Systems” SHOW-03 M. Philips (4S-Security) “People decontamination at hospital ingress” SHOW-04 T. Pauchard (Ouvry) “CBRN PPE: is the additional thermal burden unavoidable” SHOW-05 E. Guyot (Telops) "Airborne Infrared Hyperspectral Imager for Intelligence, Surveillance and Reconnaissance Applications" SHOW-08 Colonel E. Clavaud “CBRN-E threats and risks : new challenges for Fire and Rescue Services” 21:1521:30 21:3021:45 SHOW-06 Capitaine L. Hugues (CNCMFE) “CBRNe Education and Training Center” SHOW-07 G. Bielecki (Bpifrance) “Financement de l'innovation et de la supply-chain défense sécurité" CONFERENCE PROGRAM Tuesday, March 17 (AM) Medical Countermeasures (part 1) ( Amphitheater) Chairs: C. Li, E. Carniel 08:0008:45 08:4509:10 09:1009:35 09:3510:00 10:0010:15 10:1510:30 10:3011:00 MCM-01 F. Dorandeu "Medical countermeasures against CBRN threats: challenges for the future" MCM-02 R. Abergel "Development of New Therapeutics for Radionuclide Decorporation: From Discovery to IND" MCM-03 H. Thiermann "New Approches in Therapy of Nerve Agent Poisoning" MCM-04 C. Montecucco "Novel and safe inhibitors of botulism" MCM-05 A. Avril “Isolation of hyper-humanized antibodies cross-neutralizing botulinum neurotoxin A1 and A2 by targeting their heavy chain” MCM-06 P. Aas “Two medical therapies very effective shortly after exposure to high doses of soman poisoning in rats” COFFEE BREAK Medical Countermeasures (part 2) (Amphitheater) Chairs: F. Dorandeu, C. Montecucco 11:0011:25 11:2511:50 11:5012:15 12:1512:30 12:3012:45 12:4514:00 MCM-07 E. Carniel "A new and promising vaccine against plague" MCM-08 D. Gillet "Broad-Spectrum Compounds Active Against Toxins, Viruses and Parasites" MCM-09 J. Ma “Passive immunity and post-exposure prophylaxis options using plant biotechnology” MCM-10 L. Jean “Uncharged reactivators of OP-inhibited human cholinesterases” MCM-11 C. Li "Managing Internal Radiation Contamination Following a Radiological or Nuclear Emergency: A Summary of Recent Work" POSTER SESSION & LUNCH CONFERENCE PROGRAM Tuesday, March 17 (PM) Amphitheater Detection and biomarkers (part 1) Chairs: D. Pignol, M. Jett E. Fitzgerald room Medical Countermeasures (part 3) Chairs: T. Wille, E. Lemichez MCM-12 R. Hammamieh “Temporal Progression of Pneumonic Plague in Blood of Nonhuman Primate: A Transcriptomic Analysis” 14:1014:35 DET-01 M. van der Schans “Verification of exposure to Chemical Warfare Agents and Pesticides: Analysis of protein adducts” MCM-14 F. Dhote “Efficacy of HI6 dimethanesulfonate (combined with atropine and avizafone) by the intramuscular route, in VR-intoxicated cynomolgus monkeys” 14:3515:00 DET-02 R. Grunow “Benefits of a European project on diagnostics of highly pathogenic agents” 15:0015:15 15:1515:30 15:3015:45 15:4516:15 MCM-13 M. Joosen “The impact of skin decontamination on the time for effective treatment of low volatile nerve agents” MCM-15 N. Arndtz-Wiedemann “From Smallpox to Ebola: Utilizing the MVA-BN® Vaccine Platform to Address National Security and Public Health Threats” 14:1514:30 14:3014:45 14:4515:00 15:0015:15 DET-03 W. Hempel “New tools for biologial dosimetry : detection of dicentric chromosomes with telomere and centromere staining on metaphases and on prematurely condensed chromosomes permit to reevaluate the dose effect relationship and to develop automatization” MCM-16 X. Brazzolotto “Biochemical and Structural Study of a SelfReactivating Butyrylcholinesterase after V-type Nerve Agent Inhibition” DET-04 J. Armengaud ““Phylopeptidomics”, assessing without any a priori the content of any sample in terms of biological agents and biothreats” MCM-17 R. Baati “Discovery of a new class of tetrahydroacridine hybrid reactivators of nerve agent-inhibited human acetylcholinesterase” DET-05 L. Bellanger “Ebola eZYSCREEN®: a rapid diagnostic test for Ebola that takes fifteen minutes” 14:0014:15 MCM-18 S. Simon “Neutralizing Antibodies Against Ricin Toxin and Mechanism of Action” COFFEE BREAK 15:1515:30 15:3015:45 15:4516:15 CONFERENCE PROGRAM Tuesday, March 17 (PM) Amphitheater Environmental detection (part 2) Chairs: M Van der schans, E Ansoborlo 16:1516:40 DET-06 D. Pignol, "In-line multiplexed biosensing of toxic compounds in waters" 16:4016:55 16:5517:10 DET-07 M.W. Calfee “EPA’s Research to Enhance Environmental Sampling following Biological Terror Incidents” DET-08 T. Elßner “On-site multiplex detection of category A and B biothreat agents” E. Fitzgerald room Medical Countermeasures (part 4) Chairs: P. Aas, R. Abergel MCM-19 A.G. Calas “In vivo efficacy assessment of two uncharged reactivators of VX-inhibited acetylcholinesterase in Mouse compared to two reference oximes: HI-6 and pralidoxime” MCM-20 K. Kuca “Modified bisquaternary monooximes were found to be effective reactivators of human AChE inhibited by organophosphates” MCM-21 J. Bzdrenga “Study and development of a bacterial virulence inhibitor by quorum quenching” MCM-22 T. Wille “Concept to support medical service, deployed troops and political and military decision makers in case of a chemical agent attack with medical expertise” MCM-23 S. Mikhalovsky “Medical Adsorbents for Protection against CBRN Accidents” 17:3018:15 16:1516:30 16:3016:45 16:4517:00 17:0017:15 17:1517:30 17:3018:15 Special guest B. Baertschi “Bioterrorism & ethics” 18:1520:00 18:1520:00 POSTER SESSION 20:1522:00 WORKSHOP "Les outils de soutien à l'innovation" Emmanuel Guillot-Combes & Yannick Morel « La S&T de défense dans le domaine NRBC» « Les outils de soutien aux PME » Financement de la thématique « Sécurité Globale » à l’ANR GALA EVENING & DINNER 20:1522:00 CONFERENCE PROGRAM Wednesday, March 18 (AM) Amphitheater Detection (part 3) Chairs: A Alvarez, E. Ansoborlo E. Fitzgerald room Protection & Decontamination Chairs: S. Cibulsky, E. Espuche 08:0008:25 DET-09 C. Pijolat "Silicon micro-preconcentration device for the detection of explosive traces" 08:2508:50 DET-10 D. Spitzer “Synthesis of nanostructured vertically aligned titanium dioxide and cupper oxide nanotubes on sensing cantilevers” 08:5009:05 09:0509:25 09:2009:35 09:3509:50 DET-11 J.A. Tørnes “Connecting the Lightweight Chemical Detector to a headspace sampler for field detection of chemical warfare agents” DET-12 F. Arduini “Miniaturised printed biosensors for chemical warfare agents” DET-13 A. Duvauchelle .“CORIOLIS and KIM : Suitable devices for air sampling and on field biological detection” PRODEC-01 M. Watanabe “Alkali metal (including Cs) separation by chelating method in supercritical CO2 and adsorption on charcoal” PRODEC-02 G. Phan “Evaluation of the efficacy and cutaneous toxicity of a calixarene topical formulation for the treatment of superficial wounds contaminated by uranium” PRODEC-03 J. Voigt “Solar light-activated photocatalysts and functionalized textiles for self-decontaminating individual protection against toxic agents” PRODEC-04 I. Shortman “Development of improved test methods to evaluate CWA contact hazards and personal decontamination efficacy” PRODEC-05 J. Larner “Use of LC-MS urinalysis to measure systemic exposure to methyl salicylate CW simulant in a human volunteer decontamination trial” PRODEC-06 S. Shetage “HPLC-APCI-MS profiling of residual skin surface components: ‘Sebomics’” DET-14 M. Schatzmann “CT-Analyst – Fast and Accurate CBR Emergency Assessment” 09:5010:00 10:0010:30 COFFEE BREAK PRODEC-07 A. Salerno “In Vitro Skin Decontamination of the Organophosphorus Pesticide Paraoxon with Nanometric Cerium Oxide CeO2” PRODEC-08 D. Daudé “Engineering hyperthermostable enzymes for external decontamination of organophosphate chemicals” 08:0008:15 08:1508:30 08:3008:45 08:4509:00 09:0009:15 09:1509:35 09:3009:45 09:4510:00 10:0010:30 CONFERENCE PROGRAM Wednesday, March 18 (AM) Amphitheater Protection & Decontamination (part 1) Chairs: M Watanabe, D. Josse E. Fitzgerald room Detection (part 3) Chairs: J. Armengaud, B. Dorner 10:3011:15 DET-15 S. Delannoy 10:3010:45 “Use of whole genome sequencing and High throughputqPCR for identification of pertinent genetic markers associated with enterohemorrhagic E. coli: an interesting approach to improve tracking and tracing ofaccidental and deliberate contamination of food and water samples with EHECs” PRODEC-09 R. Chilcott "History of Decontamination Research" DET-16 M. Ansaldi “Phage-based fluorescent biosensors to specificallydetect enterobacteria in water" 11:1511:40 PRODEC-10 S. Cibulsky "Evidence-based principles of mass patient decontamination" 11:4012:05 12:0512:20 12:2012:35 12:3513:45 13:4514:00 PRODEC-11 K. Takeshita “Restoration technologies of water contaminated by radioactive elements released from Fukushima Dai-Ichi NPP” PRODEC-12 C. Bertrand "CBRN Personal Protective Equipment for civilian first responders: the IFREACT EC-supported project" PRODEC-13 S. Jerome “Retaining a global resource of Plutonium-244 10:4511:00 DET-17 K. Helmi “Microbiological monitoring of drinking water production process using flow cytometry: a reliable toolfor active management” DET-18 K. Boudergui “SAFEWATER - Innovative tools for the detection andmitigation of CBRN related contamination events ofdrinking water” 11:0011:15 DET-19 R. Den Dulk “FlowPad, a generic microfluidics platform for automated sample preparation and qPCR detection” 11:3011:45 DET-20 11:4512:00 F. Becher “Multiplex absolute quantification of microbial andplant toxins in complex matrices using high resolution targeted mass spectrometry and isotopically labeled protein standards” DET-21 J-M. Elalouf “Extraction of trace amounts of degraded DNA for high-throughput sequencing and reconstruction of complete genomes” DET-22 C. Feraudet Tarisse “Detection of Clostridial epsilon toxin in biological matrices by immunoassay and immunochromatography” POSTER SESSION POSTER PRIZE & LUNCH POSTER AWARD 11:1511:30 12:0012:15 12:1512:30 12:3513:45 13:4514:00 CONFERENCE PROGRAM Wednesday, March 18 (PM) Amphitheater Protection & Decontamination (part 2) Chairs: R. Chilcott, P Berard E. Fitzgerald room Detection (part 4) Chairs: C. Bossuet, F. Arduini 14:0014:25 PRODEC-14 H. Garcia "Novel photocatalyst for chemical detoxification of surfaces and water with solar light” 14:2514:40 14:4014:55 14:5515:10 15:1015:25 15:2515:40 15:4015:55 PRODEC-15 S. Sarrade “Supercritical CO2 decontamination processes for CBRN applications: an alternative to liquid treatments” PRODEC-16 Y. Hakuta “Removal of radioactive Cs137 ions from contaminated waste using Prussian Blue nanoparticles” 18:0019:00 DET-24 G. Girault “Using whole genome SNP discovery to genotype Anthrax” DET-25 E. Schultz “An experimental study of monitoring single bacteria in non-ideal conditions using Raman spectroscopy” DET-26 A. Carella “Colorimetric papers sensitive to Sarin in the gas phase” PRODEC-17 V. Keller “Photocatalytic self-decontaminating functionalized textiles towards chemical and biological agents” PRODEC-18 S. Meunier “Comparison of CBRN tests results” PRODEC-19 H. Matar “Design and characterisation of a novel in vitro skin diffusion cell system for assessing mass casualty decontamination systems” PRODEC-20 L. Cochrane “Novel comparative research on skin decontaminants” 15:5516:30 16:3017:00 17:0018:00 DET-23 J. Vanhomwegen “Rapid diagnostic tools for point-of-care testing of Ebola virus disease” DET-27 A. Alvarez “Spanish collaboration for improving solutions against CBRN threat” DET-28 R. Araoz “Bioassays development for detecting fast acting neurotoxins targeting nicotinic acetylcholine receptors” DET-29 P. Armand “CERES® CBRN-E – A fast response modelling and decision-support system to face CBRN-E threats” DET-30 S. Procureur “Muon tomography for homeland security with multiplexed Micromegas detectors” DET-31 K. Boudergui “Plastic scintillator based technic to provide Helium 3 free neutron detectors for Radiation Portal Monitor application” DET-32 J-P. Monet “Can robots enhance crisis management? Cases Study of UGVs and UAVs use for civil protection emergencies” COFFEE BREAK ROUND TABLE SESSION CONCLUSIONS 14:0014:15 14:1514:30 14:3014:45 14:4515:00 15:0015:15 15:1515:30 15:3015:45 15:4516:00 16:0016:15 16:1516:30 16:3017:00
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