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Lab Medicine 2015
Academy of Clinical Laboratory Physicians and Scientists
University of Minnesota, Department of Laboratory Medicine
and Pathology
Coffman Memorial Union
Minneapolis, MN
May 28 -30, 2015
Accreditation
This activity has been planned and implemented in accordance with the Essential Areas and
Policies of the Accreditation Council for Continuing Medical Education (ACCME) through
the joint providership of the University of Minnesota and Academy of Clinical Laboratory
Physicians and Scientists. The University of Minnesota is accredited by the ACCME to
provide continuing medical education for physicians.
This activity has been approved for AMA PRA Category 11 Credits™.
Satellite workshops have been approved for AMA PRA Category 4 Credits™.
Jointly Provided by
University of Minnesota and Academy of Clinical Laboratory Physicians and Scientists
LABORATORY MEDICINE OF TRANSPLANTATION
OBJECTIVES:
 Discuss and debate new and emerging research in the field of
transplantation research.
 Identify and describe new techniques and protocols to accuracy and
efficiency in diagnosing transplant infections and diseases.
 Identify the numerous health care professionals involved in the transplant
process and care of the transplant patient.
 Identify opportunities for collaboration with other disciplines throughout
the care continuum of the transplant patient.
 Interact with other healthcare professionals in addressing issues facing
researchers and professionals in the transplantation field.
Program
DAY 1
THURSDAY, MAY 28, 2015
8:00 a.m. – Noon
REGISTRATION OPENS
Great Hall Coffman Memorial Union (CMU)
8:00 A.M. – Noon
SATELLITE WORKSHOPS
Each workshop has been approved for
AMA PRA Category 4 Credits™.
11:00 a.m. – 1:00 p.m.
EXECUTIVE COMMITTEE MEETING
307 Coffman Memorial Union
Start of Scientific Program
Great Hall, Coffman Memorial Union
1:00 p.m.
Welcome and Introductions
Anthony Killeen, MD, PhD, Professor and Vice Chair,
Department of Laboratory Medicine and Pathology, Program
Committee Co–Chair, University of Minnesota, Minneapolis,
MN
Michael Linden, MD, PhD, Assistant Professor, Department of
Laboratory Medicine and Pathology, Program Committee CoChair, University of Minnesota, Minneapolis, MN
SCIENTIFIC SESSION I: ISLET CELL TRANSPLANTATION
Moderator: Dr. Anthony Killeen
1:15 p.m. – 1:40 p.m.
"Preclinical Research in Islet Transplantation: What do we
need to learn?"
Bernhard Hering, MD
Professor of Surgery, Director, Islet Cell Transplantation
Program, University of Minnesota, Minneapolis, MN
1:40 p.m. – 2:05 p.m.
"Clinical Research in Islet Transplantation: What have we
learned?"
Melena Belin, MD
Assistant Professor, Division of Endocrinology, Department of
Pediatrics, University of Minnesota, Minneapolis, MN
2:05 p.m. – 2:30 p.m.
A Patient’s Perspective
Greg Lee
St. Paul, MN
2:30 p.m. – 2:45 p.m.
Session I Q and A
2:45 p.m. – 3:00 p.m.
Break
SCIENTIFIC SESSION II: POST TRANSPLANT LYMPHOPROLIFERATIVE
DISORDER
Moderator: Dr. Michael Linden
3:00 p.m. – 3:25 p.m.
“The Pathology of PTLD: A spectrum of presentation”
Elizabeth Courville, MD
Assistant Professor, Department of Laboratory Medicine and
Pathology, University of Minnesota, Minneapolis, MN
3:25 p.m. – 3:50 p.m.
“Epstein-Barr Virus Vaccine: Is the End of PTLD in Sight”
Henry Balfour, Jr., MD
Professor, Department of Laboratory Medicine and Pathology
and Department of Pediatrics, Director, International Center
for Antiviral Research and Epidemiology , University of
Minnesota, Minneapolis, MN
3:50 p.m. – 4:15 p.m.
“The Clinical Management of PTLD”
Bruce Peterson, MD
Professor of Medicine, Division of Hematology, Oncology and
Transplantation, University of Minnesota, Minneapolis, MN
4:15 p.m. – 4:30 p.m.
Session II Q and A
6:30 p.m. – 9:00 p.m.
WELCOME RECEPTION
Weismann Museum, University of Minnesota
Exit first floor CMU and travel West (left)
Program
DAY 2
FRIDAY, MAY 29, 2015
7:15 a.m. – 8:00 a.m.
BREAKFAST
Great Hall, CMU
8:00 a.m. – 9:30 a.m.
YOUNG INVESTIGATOR PRESENTATIONS 1
3RD Floor Coffman Memorial Union
Transfusion Medicine
Malignant Hematology
Microbiology
Biomedical Research
Chemistry I
9:30 a.m. – 10:30 a.m.
BREAK AND POSTER SESSION
Great Hall, CMU
10:30 a.m. – 12:00 p.m.
YOUNG INVESTIGATOR PRESENTATIONS 2
3RD Floor Coffman Memorial Union
Immunology
Benign Hematology and Coagulation
Molecular Diagnostics
Laboratory Administration & Test Utilization
Chemistry II
12:00 p.m. – 12:45 p.m.
LUNCH & ACLPS BUSINESS MEETING
Great Hall, CMU
1:00 p.m. – 1:40 p.m.
COTLOVE AWARD PRESENTATION
Coffman Memorial Union Theater
-Second Floor“Progress on the Prevention of Mother to Child
Transmission of HIV’
ACLPS award presented to J. Brooks Jackson, MD, MBA
Vice President and Dean, Health Sciences and Medical School,
University of Minnesota, Twin Cities Campus
SCIENTIFIC SESSION III: TRANSPLANT ASSOCIATED INFECTIONS
Moderator: Patricia Ferrieri, MD
Professor of Laboratory Medicine and Pathology; Professor of
Pediatrics, Division of Infectious Diseases
Director, Infectious Diseases Diagnostic Laboratory,
University of Minnesota Medical Center, Minneapolis, MN
1:45 p.m. – 2:10 p.m.
“Hematopoietic Stem Cell Transplantation”
Bruce Blazar, MD
Regents Professor, Division of Pediatric Blood and Marrow
Transplantation, Department of Pediatrics, University of
Minnesota, Minneapolis, MN
2:10 p.m. – 2:35 p.m.
"CMV and Transplant. Lions and Tigers and Bears, Oh
My!"
Jamie Green, MD, Assistant Professor of Medicine and
Infectious Disease, University of Minnesota, Minneapolis, MN
2:35 p.m. – 3:00 p.m.
“Transplant Associated Molecular Infectious Disease
Testing”
David R. Hillyard, MD
Medical Director of Research and Development
ARUP Laboratories, Salt Lake City, Utah
3:00 p.m. – 3:15 p.m.
Scientific Session III Q and A
3:15 p.m. – 3:30 p.m.
BREAK
3:30 p.m. – 4:30 p.m.
BREAKOUT SESSIONS
Breakout 1
“HLA: Basic Concepts and Case Studies”
Great Hall, Coffman Memorial Union
Moderator and Presenter: Claudia Cohn, MD, PhD
Assistant Professor, Department of Laboratory Medicine and
Pathology, Medical Director, Blood Bank, University of
Minnesota, Minneapolis, MN
David Maurer, PhD
Associate Professor, Director of HLA Laboratories,
Department of Laboratory Medicine and Pathology, University
of Minnesota, Minneapolis MN
Breakout 2
Therapeutic Drug Monitoring
Room 303 Coffman Memorial Union
“Therapeutic Drug Monitoring of Everolimus in Solid
Organ Transplantation”
Moderator and Presenter: Danni Li, PhD
Assistant Professor, Director of Clinical Chemistry
Department of Laboratory Medicine and Pathology,
University of Minnesota
"Therapeutic Drug Monitoring of Busulfan in Bone
Marrow Transplantation"
William Clarke, PhD, MBA, DABCC
Associate Professor of Pathology
Director, Clinical Toxicology
Director, Point-of-Care Testing
Johns Hopkins University School of Medicine,
Baltimore, MD
Breakout 3
Solid Organ Transplantation
President’s Room, 3rd Floor, CMU
Moderator: Nicole Zantek, MD, PhD
Assistant Professor, Department of Laboratory Medicine and
Pathology, Medical Director, Special Coagulation Laboratory,
University of Minnesota, Minneapolis, MN
"Expanding the donor pool: a functional and cellular look
at normothermic ex vivo lung preservation"
Gabriel Loor, MD
Assistant Professor, Division of Cardiothoracic Surgery
University of Minnesota, Minneapolis, MN
Improving access to Kidney Transplantation - Lab
Medicine's Crucial Role"
Ty Dunn, MD, MS
Assistant Professor, Division of Transplantation
University of Minnesota, Minneapolis, MN
6:30 p.m. – 9:00 p.m.
AWARDS BANQUET
Mill City Museum, Minneapolis, MN
Buses will depart the Commons Hotel (west entrance) every
15 minutes beginning at 6:15 p.m. Buses returning to the
hotel will begin at 8:30 p.m. every 15 minutes.
Program
DAY 3
SATURDAY, MAY 30, 2015
7:00 a.m. – 8:00 a.m.
BREAKFAST
8:00 a.m. – 8:45 a.m.
ELLIS BENSON AWARD LECTURE
Christopher A. Tormey, MD, Assistant Professor
Laboratory Medicine, Yale School of Medicine
SCIENTIFIC SESSION IV – NK CELL THERAPY
Moderator and Presenter: Dr. David McKenna, MD
Associate Professor, Director of Transfusion Medicine,
Department of Laboratory Medicine and Pathology, University
of Minnesota, Minneapolis, MN
8:45 a.m. – 9:10 a.m.
“cGMP Production of NK Cells”
David H. McKenna, Jr., MD
9:10 a.m. – 9:35 a.m.
“Adoptive Therapy with Innate Lymphoid Cells”
Michael Verneris, MD
Associate Professor, Division of Pediatric Blood and Bone
Marrow Transplantation, University of Minnesota ,
Minneapolis, MN
9:35 a.m. – 10:05 a.m.
“NK Cell Therapy for Cancer and Transplantation”
Jeffrey Miller, MD
Professor of Medicine, Division of Hematology, Oncology and
Transplantation, University of Minnesota, Minneapolis, MN
10:05 A.M. – 10:20 a.m.
SCIENTIFIC SESSION IV Q AND A
SCIENTIFIC SESSION V - FANCONI ANEMIA AND BONE MARROW FAILURE
DISORDERS
Moderator: Dr. Betsy Hirsch
10:20 a.m. – 10:45 a.m.
"Dyskeratosis congenita. Disease-specific bone marrow
transplantation: Less toxicity, better outcomes
Jakub Tolar, MD, PhD
Director, Stem Cell Institute
Edmund Wallace Tulloch and Anna Marie Tulloch Chair in
Stem Cell Biology, Genetics and Genomics
Professor, Division of Blood and Marrow Transplantation,
Department of Pediatrics, University of Minnesota,
Minneapolis, MN
10:45 a.m. – 11:10 a.m.
"Fanconi Anemia: Diagnostic Dilemmas and Interesting
Clinical Cases"
John E. Wagner, MD
Executive Medical Director, BMT Program, University of
Minnesota, Masonic Children’s Hospital, Professor,
Department of Pediatrics, University of Minnesota,
Minneapolis, MN
11:10 a.m. – 11:25 a.m.
“When and how to transplant Fanconi Anemia patients”
Margaret MacMillan, MD, MS
Professor, Division of Pediatric Blood and Marrow
Transplantation
University of Minnesota, Minneapolis, MN
11:25 a.m. – 11:50 a.m.
“The role of the genomic laboratories in the evaluation of
Fanconi Anemia and bone marrow failure syndromes"
Betsy A. Hirsch, PhD
Professor, Department of Laboratory Medicine and Pathology,
Director, Cytogenetic Laboratory
University of Minnesota, Minneapolis, MN
12:05 – 12:20 p.m.
SCIENTIFIC SESSION V Q AND A
12:20 p.m.
Boxed Lunch (need to pre order)
12:45 p.m.
Executive Meeting
Satellite Workshops
May 28, 8 a.m. - Noon
Genomic Pathology: an Interactive Workshop
President’s Room, Coffman Memorial Union
Faculty
Elizabeth M. Azzato, MD, PhD, Department of Pathology and Laboratory Medicine,
Hospital of the University of Pennsylvania, Philadelphia, PA
Elizabeth Varga, MS, LGC, Division of Hematology/Oncology/BMT, Nationwide Children’s
Hospital, Columbus, OH
Basics of Mass Spectrometry for the Clinical Laboratory
303 Coffman Memorial Union
Faculty
Robert Fitzgerald,PhD, Department of Pathology, University of California, San Diego School
of Medicine, San Diego, CA
Clinical Laboratory Analytics 2015
324 Coffman Memorial Union
Faculty
Brian Shirts, MD, PhD., Assistant Professor, Assistant Director, Informatics Division,
Assistant Director, Genetics Division, Laboratory Medicine, University of Washington
Medical Center, Seattle, WA
Noah Hoffman, MD, PhD
Assistant Professor and Associate Director of Informatics and Assistant Director of
Molecular Microbiology, Laboratory Medicine, University of Washington Medical Center,
Seattle, WA