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AIHM Journal Club Entry Instructions for Authors First and Last Name: Specialty: Email: AIHM Membership. AIHM Journal Club authors are self-‐selected or invited to contribute to the Journal Club based on their expertise. Authors must be members of the AIHM. (To become a member, please visit the Become a Member page or contact the Membership Manager with questions.) 1. Title. Describe the topic and article on which this AIHM Journal Club entry is based. See the AIHM Journal Club for examples. Try to create a short title that will highlight for readers why this might be of interest to them. 2. Your name as the author(s) and a link to the journal article you are reviewing. Write your name and whatever affiliation you want to include, the title of the article being reviewed, the author(s), and the journal in which the article was published along with the date of publication. This is not a full citation. That happens below. Remember to include a hyperlink to the original journal article or abstract. An example: David Riley, MD -‐ Academy of Integrative Health and Medicine reviewing Nood E et al. Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile in the New England Journal of Medicine in January 2013. [The title of the journal article should be “linked” to the web page where the whole article or at least the abstract can be read. If you use PubMed as your search engine for the abstract remember to check in the upper right hand section of the result to see if the entire article is available as a free download through PubMed Central or the journal website] 3. Key Words. Provide up to five key words that identify areas in your AIHM Journal Club entry that will help readers find this information again or if they wish to conduct literature searches. For the example above: Keywords: Gastrointestinal, Microbiome, Fecal transplantation, Clostridium difficile infection, Diarrhea [Consider using some of the following keywords when appropriate: nutrition, dietary supplements, herbal medicine, global health, traditional healing systems, professional self care, lifestyle medicine, motivational interviewing, intro into business practice models, meditation, mind body medicine, etc.] 4. Author(s) disclosure. If you have any competing interests please note them here. Competing interests do not affect an author’s ability to write a journal club entry, they disclose interests and potential conflicts. Two potential examples: (1) The author has no disclosures at time of publication, OR (2) The author is a co-‐author on one of the cited articles. 5. Journal Club Entry – Content. Your review should be 2-‐4 paragraphs. Brevity, focus and short sentences are important— humor is acceptable. An AIHM Journal Club entry is not original research, it is commentary on original research or an important topic. The goal is to summarize key research for our readers and to link them with that research. Here is an example from a recent journal club entry on Fecal Transplantation by David Riley reviewing Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile: May 18, 2015 “This is one of a increasing series of articles on the role of fecal transplantation in gastrointestinal disorders. This study evaluated patients with recurrent Clostridium difficile infection and associated diarrhea. They were randomized to receive either vancomycin followed by bowel lavage and infusion of donor feces; vancomycin alone; or vancomycin with just bowel lavage (no donor feces). The study was stopped after an interim analysis showed that 13 of the 16 patients in the infusion Group (81%) had resolution of C. difficile associated diarrhea after the first infusion and 2 of the 3 remaining patients had resolution after a second infusion. Resolution of diarrhea associated with C. difficile infection occurred in only 4 of 13 patients receiving vancomycin alone and in only 3 of 13 patients receiving vancomycin and bowel lavage without donor feces. There were no significant differences in adverse events among the three groups. These unusually positive results are being found when FMT is used in a wide variety of gastrointestinal disorders. A recent search at the National Library of Medicine for “FMT” found 720 references. In 2011 Francis Collins, PhD asserted that his work in the human genome was less impressive than the potential represented in the Human Microbiome Project.” 6. Commentary. Comment on why and how this article and topic are important and relevant to clinicians interested in integrative health and medicine. What are the 'take-‐away' messages in 3-‐5 sentences and 1-‐2 paragraphs? An example of a commentary from the above Journal Club entry by David Riley: “This report is a part of the medical literature showing that fecal transplantation (FMT) has probably been used in more than ten thousand patients. Research suggests that microbes in our guts—of which there are ten times as many as there are cells in our body—play a role in a variety of illnesses. These illnesses range from inflammatory disorders to allergies to obesity to name but a few. OpenBiome, a nonprofit stool bank founded at the Massachusetts Institute of Technology (MIT) ships weekly specimens to hospitals around the country and the Cleveland Clinic named FMT one of the top medical innovations last year. Alterations in the microbiome are now associated with a variety of gastrointestinal disorders. In the future the association between alterations in the microbiome cause by the inappropriate use of antibiotics and a variety of illnesses will inevitably increase. For example autism spectrum disorder has already been associated with changes in the microbiome and sometimes been linked with antibiotics.” 7. Citations. List the article(s) you reviewed to write your AIHM Journal Club entry. Other relevant publications or websites may be included. Include a hyperlink to the original journal article or abstract as outlined above in Section 2. Here is an example of the citations from an AIHM Journal Club entry: • van Nood E, Vrieze A, Nieuwdorp M, Fuentes S, Zoetendal EG, de Vos WM, Visser CE, Kuijper EJ, et al. Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile.N Engl J Med 2013;368:407-‐15. • Plotnikoff G, Riley DS. The Human Microbiome. Global Adv Health Med. 2014:3(3):4-‐5. • Steve LeBeau; Alexander Khoruts, MD. Fecal Microbiota Transplantation: An Interview With Alexander Khoruts. Global Adv Health Med. 2014;3(3):73-‐80 8. Excerpt. This is important for social media. Your excerpt should be a concise (one-‐to two-‐sentences or no more than 70 words) summary of the entry that will be used by AIHM in their social media channels to promote your contribution. A possible example for the Journal Club entry on Fecal Transplantation: Fecal transplantation from healthy individuals is an extremely promising therapy for a variety of currently difficult to treat GI disorders. And the success rate is extremely high! This is especially important at a time when the over-‐prescription of antibiotics is linked with antibiotic resistance and MRSA as well as other diseases associated with an abnormal GI microbiome. This is a new frontier in medical therapies! May 18, 2015