ANALYTICAL INSTRUMENTS COMMITTEE COMPANIES COPENHAGEN Wednesday, April 15, 2015 2015 KEYNOTE SPEAKERS ESAC 2015 ∙ April 15 Martin Bizzarro, Professor & Director StarPlan - Centre for Star and Planet Formation, Natural History Museum of Denmark University of Copenhagen 2014 "Towards a recipe for making habitable worlds like Earth" Participation is free Continental breakfast, lunch, coffee & soft drinks provided. As far as we know, our solar system is unique. It could be the only planetary system in the Universe to harbor intelligent life or, indeed, life at all. Reconstructing its history is thus a fundamental goal in natural sciences. Since the discovery in the early 1990s of the first exoplanet - a distant world orbiting a star other than our Sun thousands of exoplanets have been discovered. The structure of these planetary systems and the properties of their planets are much more diverse than originally predicted, and understanding why is key to defining a recipe for making habitable worlds like Earth. In his presentation Martin Bizzarro will present new laboratory analyses of meteorite samples which were formed at the same time as our sun – and obtained using state-of-the-art techniques such as thermal ionization and plasma source mass spectrometry. Significant improvements in analytical precision allow us to uncover a wealth of previously unavailable information. He will discuss the impact of these new data for understanding planet-formation processes and, ultimately, the key ingredients for making planets like Earth. No cancellations after: Wednesday, April 8 Robert Feidenhans'l Professor of nanophysics Head of Department, The Niels Bohr Institute To register, visit: www.esac.dk by April 1 Thereafter, cancellations & “no shows” will be invoiced for DKK 500 (ex. VAT) "X-rays and neutrons: New Analytical Tools in for Research and Development." The use of X-rays and neutrons applications in material science, physics, chemistry and biotechnology is taking a quantum leap due to the invention of new technologies. These will enable completely new possibilities for the fine analysis of matter. In Lund in Sweden, two large research facilities, MAX IV and the ESS are currently being built, the latter with a significant Danish financial contribution. Both these facilities will take the world lead in exploiting these possibilities in the coming decade. In this presentation, the background for the evolution of these techniques will be given by a number of examples from recent research as well as from the collaboration with Danish industry through the industry portals at both the Technical University of Denmark and the University of Copenhagen. Event Coordinator: AmCham Denmark ∙ Christians Brygge 26 ∙ 1559 Copenhagen V Tel. (+45) 33 932 932 ∙ Fax (+45) 33 932 938 AmCham Denmark’s Analytical Instruments Committee is pleased to announce the 15th annual Executive Seminars in Analytical Chemistry: ESAC 2015. ESAC brings together manufacturers, leading scientific researchers, progressive vendors and cutting-edge technology within the field of analytical instruments. Experiences, methods, results and the latest developments will be presented within four core areas: Life Science / Biotech, Pharmaceutical, Food / Environmental and Clinical / Forensic applications. Wednesday, April 15, 2015 Scandic Copenhagen Vester Søgade 6 1601 Copenhagen V Wednesday April 15th 2015 08:30 - 09:20 Registration & Coffee 09:25 - 09:35 Introduction & Welcome by Stephen Brugger, Amcham 09:35 - 10:10 “Towards a recipe for making habitable worlds like Earth” Prof. Martin Bizzarro, Director StarPlan - Centre for Star & Planet Formation, Natural History Museum of Denmark, University of Copenhagen LIFE SCIENCE / BIOTECH 10:20 - 10:50 PHARMACEUTICAL CLINICAL / FORENSIC FOOD / ENVIRONMENTAL TITLE PRESENTATION BY TECHNIQUE TITLE PRESENTATION BY TECHNIQUE TITLE PRESENTATION BY TECHNIQUE TITLE PRESENTATION BY TECHNIQUE Protein Structure Iain Campuzano UPLC/MS Innovative LC Solutions Ken Cook UHPLC/MS Structure Elucidation of Natural Federico Cozzi, GC-APCI- Time of flight mass spectrometry Dr. Martin Josefsson, MS/MS Determination in Biopharma: Amgen Inc. for Increased Productivity Thermo Fisher Products from Plants by GC-APCI- University of qTOF (TOF-MS) for the analysis of new National Board of Scientific qTOF Copenhagen psychoactive drugs (NPS) in Forensic Toxicology, humans. - Experiences from the Sweden From Membrane top Monoclonal Antibodies national laboratory of forensic toxicology in Linköping Sweden 10:50- 11:20 Coffee break 11:20 - 11:50 Advanced, Multichannel Reinaldo Almeida, Approaches and Fadi Abou-Shakra, UHPLC Workflows in Department of Strategies to Meet the PerkinElmer Lipidomics LC-MS Biochemistry and Requirements of USP 232 Molecular Biology, and ICH Q3d for ICP-MS of Southern University of Analysis of Drug Products Denmark UHPLC ICP-MS Environmental Marine Harald Hasler- Forensic Toxicology Screening Petur Dalsgaard, Metabolomics: from Molecule to Sheetal, Biologisk with QTOF and UNIFI Retskemisk Institut, Ecosystem Institut, University LC/MS KU Southern Denmark 11:55 - 12:25 LC/NMR Mass Spectrometric Methods Tuulia Hyötyläinen, Recent Advances in Kenneth Thermann The use of On-line HPLC as a Tool Gregers Hendrik Genomic Profiling of Cancer LarsJønson, Center for Biomarker Discovery and Metabolomics, LC-NMR Techniques – Kongstad, for Optimization and Monitoring Hansen, Arla Foods Patients in Phase 1 Trial – for Genomic Clinical Diagnostics Steno Diabetes Fighting Fungi and Type University of of a Multi-channel Dairy Ingredients Group Personalized Medicine Medicine, Center 2 Diabetes Copenhagen Bioprocess HPLC NGS Rigshospitalet 12:25 - 13:15 Lunch Break 13:25 - 14:00 “X-rays and neutrons: New Analytical Tools in for Research and Development” Professor Robert Feidenhans’l, Head of Department, The Niels Bohr Institute 14:10 - 14:40 Characterization of Scott Gillingwater Nanometer-Thick Organic PerkinElmer MALDI-TOF Increasing Recovery Lesley Schultz, Automated Ultra Trace Analysis with Dr. Jens Luetjohann, MALDI-TOF Mass Spectrometry: Jens Jørgen Elmer Rates, Reproducibility Agilent Liquid Atmospheric Pressure Gas Galab Laboratories- Applications in Clinical Christensen, Layers Functionalized and Throughput in Technologies Handling Chromatography (APGC) – the Hamburg, Germany Microbiology Slagelse Sygehus Nanoparticles using Ambient Pharma Through Robot Sensitive and Selective Way Ionization Mass Spectrometry Automated Micro UPLC Orbitrap Technology – A Magnus Olin UHPLC/ Fantastic Tool also for Robust Thermo Fisher Highres MS Routine Quantitation Scientific TOF-MS APGC Chromatography on an AssayMAP Bravo. 14:45 - 15:15 High Quantification Michael Barrett Efficiency in Plasma Targeted Andersen, Bruker Proteomics with a Full- Daltonics Odense capability Discovery q-TOF Platform 15:25 - 15:45 Coffee Break, wrap up & prize drawing LC/MS Efficient LC Method Rune Buhl Ultrafast Acquisitions for the Fadi Abou-Shakra, Development Frederiksen, Determination of Nano Single PerkinElmer Waters A/S Particles by ICP-MS ICP-MS