PROGRAM THURSDAY 6TH FEBRUARY Registration Opens 1:00 pm Mantra Lobby Welcome Address 4:00 pm - 4:10 pm Richard Simpson, President Australasian Proteomics Society Heritage Ballroom Keynote Lecture 4:10 pm - 5:00 pm Heritage Ballroom Chair: Richard Simpson Marius Ueffing Quantitative analysis of protein complexes over space and time abs#001 Ken Mitchelhill Young Investigator Award Lecture 5:00 pm - 5:45 pm Heritage Ballroom Session sponsored by Chair: Richard Simpson Suresh Mathivanan Are biologically active exosomes stable in blood plasma? abs#002 Symposium One: Students of APS (SoAPS) 5:45 pm - 7:00 pm Chairs: David Greening, Stuart Cordwell 5:45 PM 6:00 PM 6:15 PM 6:30 PM 6:45 PM Heritage Ballroom Session sponsored by Christina Yip First report of differences in the TRAP-stimulated platelet releasate between children and adults using two dimensional Differential-In-Gel Electrophoresis (2D-DIGE) abs#003 Juan Martinez-Aguilar Selected reaction monitoring to assay the S100 protein family in colon and thyroid neoplasms abs#004 Ruth Fuhrman-Luck Determination of the kallikrein-related peptidase 4 degradome in prostate cancer identifies novel cancer-associated functions abs#005 Benjamin Raymond Global analysis of protein-protein interactions important for the virulence of Mycoplasma hyopneumoniae abs#006 Katherine Wongtrakul-Kish Adipose-Derived Stem Cell Differentiation: Changes in the Membrane Glycome and Proteome abs#007 Welcome Reception 7:00 pm - 10:00 pm Exhibition Hall Session sponsored by FRIDAY 7TH FEBRUARY Breakfast Workshop (Thermo Fisher Scientific) 7:30 am - 9:00 am Symposium Two: Post-translational Modifications 9:00 am - 10:30 am Chairs: Andrew Webb, Stuart Cordwell Heritage Two Heritage Ballroom Session sponsored by Don Hunt Innovative instrumentation and technology for the characterization of intact proteins on a chromatographic time-scale abs#008 Benjamin Parker Phosphoproteomics with data-independent mass spectrometry reveals novel features of insulin action abs#009 Rob Parker Phosphoproteomics of the cellular response to MAPK blockade in V600E BRAF mutant cells 9:00 AM 9:40 AM 10:00 AM abs#010 Morning Tea 10:30 am - 11:00 am Exhibition Hall Symposium Three: Interactome / Systems Biology 11:00 am - 12:30pm Chairs: Mark Wilkins, Michelle Hill Session sponsored by Anne-Claude Gingras Dynamic signalling interactomes in health and disease abs#011 Marc Wilkins Lysine and Arginine Methylation Modulate Protein-Protein Interactions in Intracellular Networks abs#012 Derek Wilson Conformational Disorder in Protein Function and Pathogenic Aggregation abs#013 11:00 AM 11:40 AM 12:00 PM Lightning Talks One 12:30 pm - 1:00 pm Chair: Ben Crossett 1st – 2nd 3rd 4th – 5th – 6th – Heritage Ballroom Heritage Ballroom Session sponsored by Laura Dagley Automated sample preparation via rapid on-line trypsin digestion prior to mass spectrometry abs#101 Krishneel Singh The surface characterisation of rat adipose derived stem cells for bone tissue engineering abs#102 Mark Ritchie Data independent LC-IM-MS strategies for the multi-omic scale identification and quantitation on cytochrome P450 transfected hepatocytes abs#103 Benjamin Lau The chromoplast proteome of oil palm fruit abs#104 Samira Aili Characterising the peptide and protein diversity of Neotropical and Australian ant venoms and the identification of novel peptide toxins for bio-insecticide discovery abs#105 Kasper Engholm-Keller Signal integration by protein phosphatase regulatory proteins mediate changes to the synaptic vesicle cycle abs#106 These 6 lightning talks will be the first 6 posters in poster session one. Notices - Erskine Walk Tour Information - Nick Williamson Lunch / Poster Session One 1:00 pm - 2:30 pm Erskine Bus / Walk Tour 2:00 pm – 3:30 pm Exhibition Hall Mantra Lobby Symposium Four: Trafficking and Vesicles 5:00 pm - 7:00 pm Chairs: Richard Simpson, Andrew Hill 5:00 PM 5:30 PM 6:00 PM 6:30 PM Heritage Ballroom Session sponsored by Andrew Hill The role of exosomes in neurodegenerative diseases abs#014 Jens R. Coorssen Vesicular 'Omics: Defining the release-ready and Ca2+-triggered fusion steps of regulated exocytosis abs#15 Dolores Di Vizio Functional and quantitative proteomic analysis of two distinct populations of extracellular vesicles from the same cell source abs#16 Dominque de Kleijn Plasma extracellular vesicles proteomics identifying prognostic and diagnostic cardiovascular biomarkers abs#17 Students of the APS (SoAPS) Dinner with Invited Speakers 7:30 pm – 9:00 pm Mantra Dining Area SATURDAY 8TH FEBRUARY Breakfast Workshop (AB SCIEX) 7:30 am - 9:00 am Heritage Two Symposium Five: Emerging Technologies 9:00 am - 10:40 am Chairs: Peter Hoffmann, Nick Williamson Heritage Ballroom Katie Southwick Targeted Protein Quantification Using High Resolution and Accurate Mass: A More Selective and Higher Throughput Way to Precisely Determine the Amount of Your Protein of Interest 9:00 AM abs#018 Jeremy Wolff Characterization of Biomolecules with electron detachment dissociation and negative electron transfer dissociation abs#019 Stephen Tate Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition abs#020 Christine Miller IMS-MS Analysis of Transmembrane Spanning Peptides abs#021 Srinath Krishnamurthy Solving the data analysis bottle neck in Hydrogen Deuterium Exchange MS experiments 9:20 AM 9:40 AM 10:00 AM 10:20 AM abs#022 Morning Tea 10:40 am - 11:00 am Symposium Six: Clinical / Disease Proteomics One 11:00 am - 12:15 pm Chairs: Hubert Hondermarck, Tony Purcell Exhibition Hall Heritage Ballroom Session sponsored by Maxey Chung Stathmin-1 in colorectal cancer metastasis: From proteomics to functional and mechanistic studies abs#023 11:30 AM Patricia Illing Prospecting for polymorphisms: high resolution mass spectrometry elucidates distinct peptide-binding capacities across allelic variants of Human Leukocyte Antigens abs#024 11:45 AM Peter Hoffmann Autoantibody biomarkers for the detection of early stage ovarian cancer abs#025 12:00 PM Swetlana Mactier Identification of Protein Markers for Survival in Lymph Node Metastases from Stage III Melanoma Patients abs#026 Lightning Talks Two 12:30 pm - 1:00 pm Heritage Ballroom Chair: Ben Crossett Session sponsored by 11:00 AM 1st – 2nd 3rd 4th – 5th – 6th – Giuseppe Infusini The hunt for wound healing factors in plasma: a label-free quantitation application to target discovery proteomics abs#201 Thilo Bracht Proteome analysis of a hepatocyte-specific BIRC5-knockout mouse model during liver regeneration abs#202 Karlie Neilson Quantitative proteomic analysis of compensatory pathways in yeast deficient of the thiamine biosynthetic enzyme, Thi4 abs#203 Michelle Hill Online Quantitative Proteomics p-value Calculator for Permutation-Based Statistical Testing of Peptide Ratios abs#204 Anup Shah Mammalian Lipid Raft Proteome Database abs#205 Fiona Durand The induction of plasma membrane proteins in response to stress abs#206 These 6 lightning talks will be the first 6 posters in poster session two. Lunch / Poster Session Two 1:00 pm - 2:30 pm Exhibition Hall Passport Award Ceremony 2:15 pm Exhibition Hall Symposium Seven: Biological Applications of Proteomics One 2:30 pm - 3:45 pm Heritage Ballroom Chairs: Ben Crossett, Steven Djordjevic Session sponsored by 2:30 PM 3:00 PM 3:15 PM Albert Sickmann Systematic characterization of human platelets in arterial vascular disorders by quantitative proteomics abs#027 Andrew Webb Crosslinking and HDX identify a second, decoration-independent, binding interface is the site for actin filament severing by ADF/Cofilins abs#028 Nathan Croft Systems biology analysis of virus-host interactions: kinetics of antigen and epitope display abs#029 3:30 PM Vera Ignjatovic Differences in platelet proteome and secretome between children and adults: the role in protection from thrombosis and cardiovascular disease abs#030 Coffee Break 3:45 pm - 4:15 pm Symposium Eight: Clinical / Disease Proteomics Two 4:15 pm - 5:45 pm Chairs: Mark Molloy, Lou Fabri Exhibition Hall Heritage Ballroom Session sponsored by 4:15 PM Kai Stϋhler Aging – Identification of proteins associated with in situ aging using a quantitative proteome approach abs#031 4:45 PM Srinath Krishnamurthy How enzymes access caged substrates? Monitoring hydrolysis of receptor-bound cyclic AMP by phosphodiesterases using amide hydrogen/deuterium exchange mass spectrometry abs#032 5:00 PM Tai-Long Pan Vimentin modulates invasion and metastasis in human hepatocellular carcinoma cells abs#033 5:15 PM 5:30 PM Ralf Schittenhelm Deciphering the HLA B27 immunopeptidome abs#034 Allan Stensballe Discovery and targeted proteomics in the light of the eye APS Carnival 7:00 pm – 12:00 am Session sponsored by abs#035 Mantra Dining & Seagrass Lawn Area SUNDAY 9TH FEBRUARY Breakfast Workshop (Waters) 7:30 am - 9:00 am Heritage Two Breakfast Workshop (Thermo Fisher Scientific) 7:30 am - 9:00 am Heritage Two Symposium Nine: (Bio)informatics 9:00 am - 10:30 am Chair: Shoba Ranganathan, Michelle Hill 9:00 AM Heritage Ballroom Session sponsored by Shoba Ranganathan Unlocking the Puzzling Biology of the Black Périgord Truffle Tuber melanosporum abs#036 9:30 AM 9:50 AM 10:10 AM Shivashankar Hiriyur Nagaraj A novel, integrated software for proteogenomics abs#037 Jason Wong Proteogenomics analysis identifies mutation specific post-translational modifications and novel proteins in human cell lines abs#038 Chi Nam Ignatius Pang Tools to Covisualize and Coanalyze Proteomic data with Genomes and Transcriptomes: Validation of Genes and Alternative mRNA Splicing abs#039 Morning Tea 10:30 am - 11:00 am Symposium Ten: Biological Applications of Proteomics Two 11:00 am - 12:15 pm Chairs: Bill Jordan, Steven Djordjevic Session sponsored by 11:00 AM 11:40 AM Exhibition Hall Heritage Ballroom Helmut E Meyer Tissue Based Proteomics for Biomarker Discovery abs#040 Brad Walsh Identification of the MIL-38 target antigen for the diagnosis of prostate cancer abs#041 11:55 AM Ben Herbert Serum and urine biomarkers correlate with decreased cartilage degradation after adipose stem cell treatment in double blind trial for knee osteoarthritis abs#042 Closing Ceremony / Award Presentation / AGM 12:20 pm - 1:00 pm Chair: Richard Simpson Heritage Ballroom APS Annual General Meeting 1:10 pm - 1:45 pm Chair: Richard Simpson Heritage Ballroom Buses Depart Buses depart at 2:00 pm SHARP Mantra Lobby