Monday 08th June 2015
Location
12.30-14.00
Registration and Exhibition/Posters
Sandwich Lunch on arrival
14:00
Welcome
SWC Lecture
Theatre
NF-B AND STRESS RESPONSES
SWC Lecture
Theatre
14.00-14.25
It takes more than one HIF to control NF-kappaB
Sonia Rocha, University of Dundee
14:25-14:50
Dissecting the mechanism of FAK-regulated NF-KappaB signaling.
Delphine Lees (Hodivala-Dilke lab)
14:50-15:15
Regulation of NF-kappaB by hypoxia and hypercapnia
Cormac Taylor
15:15-15:30
Short talk: Modulating stress-stimulation of NF-kappaB: role of the nucleolus.
Jingyu Chen (Stark lab)
15.30-16.00
Coffee Break and Exhibition/Posters
16.00-16.25
Carbon dioxide dependent regulation of NF-kappaB
Eoin Cummins
16:25-16.50
NF-kappaB and DNA replication stress
Neil Perkins
16.50-17:05
Short talk: Mitochondria dependent NF-kappaB activation links apoptosis to innate
immunity
Evangelos Giampazolias (Tait lab)
17.05-18.00
Drinks Reception and Exhibition/Posters
Tuesday 09th June 2015
08.00-09.15
Registration
UBIQUITIN AND NF-B
09.15-09:40
09:40-10:05
SCW Foyer
SCW Foyer
SWC Lecture
Theatre
SWC Foyer
Location
SCW Foyer
SWC Lecture
Theatre
Autophagy of TRAF3 regulates interleukin expression via control of novel NFkappaB/TGFbeta crosstalk
Alice Newman (Wilkinson lab)
The role of E3 ubiquitin ligases in the activation of the canonical IKK complex.
Philip Cohen
10:05-10:30
Regulation of Met1-linked ubiquitin chains by OTULIN
Rune Damgaard (Komander lab)
10:30-11.00
Coffee Break and Exhibition/Posters
11.00-11.25
Lys-63-linked ubiquitin is functionally required for NOD2 signalling and is regulated by
the linkage-se;ective deubiquitinase CYLD.
Mads Gyrd-Hansen
11.25-11:50
Lubac and linear ubiquitin coordinates DUB recruitment to signaling complexes.
Peter Draber (Walczak lab)
11:50-12.05
Short talk: Novel MyD88 mutations in lymphoma and their potential effect on
transcriptional and translational control
Ming Wang (Du lab)
SCW Foyer
SWC Lecture
Theatre
12.05-13:30
Lunch and Exhibition/Posters
NF-B AND CANCER
13:30-13:55
Developing first-in-class selective IKKalpha inhibitors.
Simon MacKay
13:55-14:20
Selective targeting of the NF-kappaB pathway in cancer
Guido Franzoso
14.20-14:55
New insights into the function and regulation of the non-canonical NF-kappaB pathway
Alessio Iannetti (Perkins lab)
14.55-15:10
Short talk: The potential of IKkalpha as a novel target in ER positive breast cancer.
Joanne Edwards
15:10-15:30
Coffee Break and Exhibition/Posters
15:30-15:55
NFKB1: a suppressor of ageing and cancer.
Derek Mann
15.55-16:30
Selected short presentations from posters (5mins each)
SWC Foyer
SWC Lecture
Theatre
SCW Foyer
SWC Lecture
Theatre
Role of c-Rel in renal fibrosis: Jack Leslie
Disturbed flow induces the expression of the NF-kappaB negative regulator Cezanne
Neil Bowden
A role for p62 in nucleolar accumulation of RelA.: Pierre Morin
USP7 iinhibition modulates inflammatory and Osteolytic potential in primary human
cells. Felicity Herrington
Enhancement of NF-kappaB signaling by KLF2 inactivating mutations in splenic
marginal zone lymphoma: Alexandra Clipson
The role of Bcl-3 in skeletal heath and disease: Hussain Jaffery
Co-development of DTP3 and its biomarkers to therapeutically target the NF-kappaB
survival pathway in multiple myeloma: Laura Tornatore
SWC Foyer
16:30-18:00
POSTER SESSION
19:00 till late
Dinner and Ceilidh
Student Union
Wednesday 10th June 2015
NF-B SUBUNITS
09:30-09:55
Bcl-3 and Tpl2
Ruaidhri Carmody
09:55-10:20
Regulation of fibrosis by cRel
Fiona Oakley
10:20-10:35
Short talk: The structural basis of the p50:p50:HDAC1 interaction
Tyrell Cartwright (Mann lab)
10:35-10:50
Short talk: Mapping the interaction of BCL3 and p50 identifies Bcl-3-mimetic antiinflammatory peptide: Patricia Collins (Carmody lab)
10.50-11:30
Coffee Break and Exhibition/Posters
11:30-12:00
Regulating the nuclear distribution of RelA
Lesley Stark
12:00-12:30
Oscillations
Mike White
12:30
Finish (packed lunch available to take away)
Location
SWC Lecture
Theatre
SCW Foyer
SWC Lecture
Theatre
SCW Foyer