Yrpaiuc*urt xapgionoriuuufi xypnan 3/201 2 3uicr Contents OpurinanbHi EocniE)KeHHs Aprepia"rnua rinepreua ia Por u Herpagutlii,taux .l Fl H il ri e cep ueBo -cyAr4 H H o ro naroreHe3i rinepronivnoi xeopo6r 14 / Original articles / Arterial hypertens ion 15 The state of nontraditional cardiovascular risk factors in pr43r4Ky e pathogenesis of essential hypertension Jl.A. Miulexxo L.A. Mishchenko - Mera po6oru EocniArru noKa3HilKtt, u]o xapaKrepil3ynru uera6onirHi i nposananuHi npoqecn, ra npocrexilTr,t ix ss'Rsox a piaHeur aprepianrHoro rrcKy y xBopt4x Ha rineproHirHy xaopo6y (lX).297 naqieHrau s [X npoeegeuo KoMrleKCHe rriHilHe o6crexeHHr, 4o6oee tr,toHiropyaaHHn aprepianuHoro rrcry (AT),6ioxitvtiqHe 4ocrigxeHHr xpoai (aueHareHHn piaHia C-peaxrraHoro 6inxa, ceroeoi Kt4cflo14, Si6prHoreHy, rarcKo3t4, itvtyHopeaxrueHoro iHcyliHy, rinigHoro cneKTpa rpoei, uanoHoaoro piarugeri4y ri arruauocri cynep6Kcr4A.qilcMyrasr) ra Ao6oaol ceri (anaHareHHn uirpoanu6yuiHypii (MAV)). lpyny rourporro craHoBr4ll14 62 oco6r,r 3 HopMarbHfiM piaHervr AT. noxasaHo, ulo Anfl xBopl4x Ha [X xaparrepua amnaaqiR tecneqn@irHoro cr4creMH0ro 3anafleHHfl, 0KC[AaHTH0ro crpecy Ha rni gH[xeHHR arrraHocri aHTil0KCIAaHTHnx SepueHrie, nopyueHHfl ByrfleBoAHoro i nyprroaoro o6ruiHy i MAV. Vxaopr,lx Ha l-X pieeHr C-pearrnauoro 6inra i cerosoi Kt4cJloTl4 npnuo i He3anexHo ai4 airy ra qeHrpanbHoro oxnpiHHr noa'qsaH[ri 3 noKa3HilKaMil AT, nr sa AaH[Mr4 oQicumx aruiprcaaHu, rar l[o6oaoro NoHiropyaaHHn. HesarexHnvl aip sasnareHnx rpa4rqir,rHr,rx Saxropie cepqeBo-cyflt4HHoro pt4st4Ky e 3B'R3oK MAV i arvricry Si6prHoreHy e pioHeu au6yraropHoro AT. PagroHyrnugHae oLleHKa reMoAuHaMilru u Qun* 22 Badionuclide assessment of hemodynamics and filtra- rpaunoHHo-orcrperopHofi QyHxqrr noqeK y 6onuHurx c caxapHbrM gra6erou h runeproHr,rqecrofi 6o- tion-excretory function of the kidneys in patients with fle3Hbto V.N. Slavnov, G.A. Zubkova diabetes mellitus and essential hypertension B.H. Cnaexoa, F.A. 3y6xoea flpnae4eust pe3yflbrarbt ttccflefloBaHilr cocTonHr4fl BHyrpunogegHofi reuoguHaurxr (apeuenn aprepilanbHoro np[ToKa I BeHo3Horo orrora), QrnurpaqnoHHo-3KoKperopHora SyHxqr,fl,l noreK y 84 6oruHurx c caxapHbtM 4na6erou (C[) 2-ro ruta:42 - 6es gra6errrecroil HeSponarun (AH),24 - c IH ll r lll cra4uu r,r 18 - 6es ,QH c rnneproHreecrotl 6oneeHuo. lrHaunrecxym cquHrurpaQnn noeeK npoBo.q[tu c n0M0lLlbro cqrHrnnnRqnouHott rouorpaSrrecxoti taMMa-KaMepbr c Icn0nb30BaHileM HeSporponuor0 [penapaTa eetTc-AuernleHTpuaMilHneHTaaqerara. V 6oluHurx c C! 2-ro r[na 6ee,[H c 4nureluHocrbo 3a6oneBaHuR 6olee 12 rer ycraHoaneHur HapyueHfiR KaK BHyrpunO'{etHoil reuogruaMuKt4, raK c r[neproHl{qecroil 6one:Hsto ll cra4ru r SururpaqrorHo-oKcKperopHoI Synxqnu oTMeyeHo 3aMeAreHue aprepfianbHoro np[ToKa I no,ler. V 6onuHulx c BeHo3Horo orr0Ka, C[ 2-ro rnna a raKxe 6es [H cHt4xeHhe orcrperopHofi $yHrqrr noqeK, AocroBepHoe [oBbtueHre QnnurpaqnoHHor,t Syurquu norer. f ricru xilrre ra ii euinr Ha ui aHrnrinepreH3ilBHoro 26 Quality of life and its changes under antihypertensive niryeanun: pe3ynbraril 6-rr/icq,rHoro cnocrepexeHHe treatment: results of 6-month observation f.A. Pa.q,{exxo, l.M. Mapqoeexro, lO.M. Cipenro G.D. Radchenko, l.M. Martsovenko, Yu.M. Sirenko xrrrn naqieHrie s aprepiaruHon rineprersieo, nri 6paru yqacTb y uecruMicR,{HoNy cnocrepexeHHi, sMiHfi ni4 anrnaou aHTilrinepreH3ilauoi repanii. 3 qiem ueroo 6yno o6crexeHo 1055 naqieHria a pisHurvr cryneHeM ni4arqeHnn aprepianuHoro rncry, nri cnocrepiralncn fliKapflMt4 earanuHoi npaKruKr4. Bciu naqienrav Ha norarKy ra a xiHqi cnocrepexeHHfl npoBoAunil aHKeryBaHHfl 3a uKaaolo SF-36 Aln oqiHxn nxocri xrrrn. ,[ocni4xeHHfl noKa3ano, L4o xaopi ManH 3HaeHe, nopiaHnno ai s4opoaoo nonynnqien, 3HHXOHHT oqiHor sa aciNa nora3HIxaun Rxocri xurrq. 3araruHur,r nora3Hnx Sisnrnoro KoMnoHeHra 3A0p0B'fl 6ya aHarHo 3H[xeHuM, ToAi nK saranuH]4il noKa3H[K ncuxi.tnoro KoMnoHeHTa 3EopoB'fl cyrreBo ne ai4pisnnacr ai4 uopruanuuoro 4rn nonyrnqii. AHrurinepreHanaHa repaniR cnpuflna noKpaqaHHo 6inuuocri rolrnoHeHris sxocri xnrrR, Rri, ariN, He AocflranI piann s4opoaoi nonyrrqii. HaaegeHo pe3ynbTart4 oqiHru Rxocri ra ii Ukrainian Journal of Cardiology 3/20 1 2 Oco6ennocrta reMoAil HaMr rr ra rlepe6poaacryrnpHofi peaKril B Hocn4 B KaporhEHov r se pre6 po6asrann p norta 6acceinax y 6orsuurx c apreptaanbHofi rrnepreusreil nepeoil creneHil 38 Hemodynamic and cerebrovascular reactivity charac- teristics in carotid and vertebrobasilar circulation in patients with first degree arterial hypertension T.A. Mangiliova, Yu.E. Pavlovskii, Ye.A. Pastukhova T.A. MaHrnneea, lO.O. l'laenoecxl,ri, E.A. flacryxoea onpe4eleHrR oco6eHHocteil reuognHaurK[ [ Ba30N40T0pH0t4 peaKTilBH0crr4 MarhcrpaflbHurx qepe6paluHbtx cocy4oB, npuHa.qnexau][x aepre6po6ae[nflpHoMy 6acceilHy 6acceuHy coHHbrx apreprt,l, y 53 naqreHroB c apTepflanbHot4 rfinepTeH3ilef (Al-) 1-r,r creneHu u 36 o6cne4oaaHHbtx c HopManbHbrM I4n[ onr[MarbHbrM apTepnanbHbrM AaBneHr4eu (A[) np0Boflfiail ynbrpa3ByKoBoe AynneKCH0e ,[ln r r I cKaHI4poBaH[e 3KcTpaKpaHranbHbrx oT.qelloB coHHbtx no3BoHolHbrx apreprri il TpaHcKpaHuanbHoe cKaHilpoBaH[e cocyfloB roroaur. V c A[ autRsneHut 6oree Hfi3K[e [t4KoBbre c[crofl!4yecKile cKopocrt4 KpoB0T0Ka B [03B0H0rHbtx aprepfirx, reu y xeHulnH 6ea xeHU.ll4H A[. Pesepe Ba3oflilnaraqilr4 ocHoBHorI aprep[[ KaK y xeHU]r4H, TaK il y Myxrl[H ocHoBHoil rpynnur 6uln Hilxe, reM B rourponuHot,l. l4gueHeHnR Kp0BOToKa B 6accefiHe coHHbrx aprepr,ril y 6onuuurx c A[ Hocmrr pa3HoHanpaBneHHuril Heycror,rrraurfi xaparrep" BasouoropuaR peaKT[BH0crb cpeflHeI Mo3r0Bori aprepilr He oTnIraracb y o6cnegoaaHHbtx c noBbtueHHbtM t4 HoprrlanuHurrvr A,[. noBblueHilr llonyreuuste flaHHbte cBil[erenbcTBytoT 0 Harilril[ ngveHeHuil reM0A[HaMIKr4 14 ToHyca e aepre6po6aa[nflpHoM 6acceilHe aprepril y 6oruHurx c Al- 1-r,r creneH[, 6olee aurpaxeHHbtx y xeHU.ll4H c noaurueuHurrvr A,[. Aplrruii cepu, FanerrrH-3 y 6onbHbrx c Qm6prannnqraefi npe4cepgrai B.14. [enyixo, 3.C. Baurarlr,q3e, / n03B0HoyHbtx Cardiac arrhythmias 45 Galectin-3 in patients with atrial fibrillation V.l. Tseluiko, Z.S. Vashakidze, T.V. Motylevskaya, T,B. MoruueBcKac, H.A. OnonoHcKag N.A. Opolonskaya flpoaHalnerpoBaHbt B03MoxHbte KoppenfluiloHHbre cBs314 ypoBHr raneKTrHa-3 c Qarropauu p14cKa fi Klt4H14Ko-aHaMHecrilrecKilM14 flaHHblMH, loKa3areflflMl4 xonrepoBcK0ro MoHl4Topl4poBaHnn oKI- il TpaHcMr4TpanbHoro KpOBoToKa y naqileHToB c nap0Kcr43ManuHora r nepcilcrl,lpytolleil Soplaur Qr6purnnquu npe4cep4rrI. lloautuJeHHu[4 ypoBeHb loKa3areflr accot14t4pOBaH c cynpaBeHTpr,lKynrpHbtMt4 HapyueH[flMt4 pl4rMa, eacrbrMr4 npficrynaM[ Qu6pnrrnqrr npeAcepflrfi n yBen[reHHbtM pa3MepoM neBoro [peA0ep4nn. ,[orasaHa 3aBilct4Mocrb MexAy flilHaMl4xotl ypoaHn ranerruHa-3, Kr14H14recKrM TeqeH!4eM nporH030M ga6oreeaH[s. I ilaporcnsvaruua Qi6prannrlin nepe4cep4u y paHni repuiuu nicnn onepaqii aoproxopoHapHoro uyHry- 50 Paroxysmal atrial fibrillation at early terms after coronary artery bypass grafting B.M. Todurov, O.l. Zharinov, O.A. Yepanchintseva, O.P. Nadorak, Yu.A. Borkhalenko, N.V. Ponych, l.V. Shvets, l.V. Shklianka BAHH9 E.M. Togypoe, O.ff. )(apixoe, O.A. €nax,{iHqeBa, O.II. Ha4opax, lO.A. Eopxanenro, H.B. floxrav, l.B. llleeqt, l.B. llJxncHxa Mera 4ocni4xenuR - oqiHnrn npe4ilKTopu Br4H14KHeHHfl Qi6prnquii nepe.qcepAb (Ol-l) y naqieHria s iuer4irHoo xaopo6oro ceprln (lXC) nicnn onepaqii a0pr0K0p0HapHor0 uyHTyBaHHn (AKIX). V npocnerruaroMy o.qHoqeHrpoeouy gocri4xeHHi npoaHanieysarr AaHi, orpuuaHi npn xniniro-incrpyueHranbHoMy o6crexeHHi 174 naqieHria 3 lXC. Ol'l y paHHir,t nicnnonepaqir,turil nepiog 4iarHocryoarr 3a flaHilMn 6eanepepenoro uoHiropyaaHHR EKI npornrou 48-72 ron uJflFXoM pyrrHHoi u1ofleHHoi peecrpaqii EKI y 12 ai4aegeHHrx, a raKox npu npoae4euHi xolrepiacuroro r/loHiropyaaHHr EK[. BcraHosneHo, rqo ph3uK Br,lHr4KHeHHq Qn craHoBt4rb 33 % y naqieHria nicln AKL]1, 49,1 % - nicnR noe,qHaHHq AKII ie KrtanaHHilM npore3yBaHHflM. 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Solovyan Uelu rcclefloBaHur - t43y9t4Tb [0Ka3areril crpyxrypHo-QyHKqr/0HanbH0r0 cocrorH14f M14oKapEa, aapl,ta6enutocrI pITMa, 3fleKTpoQ[3t4orl0t[recK[e caotlcraa cepflqa n r4x B3ar4MocBfl3u c racrororl I AJr[TeabHOcrbo napoKct43Moa Sr6pnnlnqur,,| npegcep4rr.t (Ol-l). B t4ccllefloBaHile BKroqeH0 343 naqreHra c [ap0Kcr43r\iranuHor,r OI HeKflanaHH0r0 reHesa. B rpynny 1a eouril 263 6ortHurx c YacrblM14napoKCt43[4aMIIOll (1 pasBHeAenorvaule),416-80cpeEKilM14 (pexel paaauegenrc); B r-pynny2aaxno,][nil291 naqreHra c nn[TeflbHocrbo napoKcl43Ma < 48 q, B 26 - 52 6onuHutx c An[renbHocrbo napoKcr43Ma > 48 r. 14cnonu3oBanu [ByMepHyto 14 [o[nflepexorap4rorpaS[o, xonrepoBCK0e [4oHr4TopldpoaaHre 0K[ c aHaJ]il30rvr eapna6eruHocr[ pilrMa cepAr]a. OyHrquru npoeo4nqeil crcreMbr cepflqa n yr3B14Mocrb npe4cep4ril fi3yranI npI epecn14u]eBoflHoM enerrpoQl,laroflor[recKoM ilccaeAoBaHnil. 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Arepocrcaepoa, iruenrirrHa xBopo6a cepufl Mosroerfi narpiilyperrarnrarT nenrh4 qK / Atherosclerosis, ischemic heart disease 65 Brain natriuretic peptide as early marker of remodeling after myocardial infarction: outcomes of a cohort study O.Ye. Berezin, T.O. Samura MapKep paHHboro nicrniHQaprrHoro peMoAenoBaHHq: pe3y- braril KoroprHoro gocligxeuun O.€. Eepesix, T.O. Cauypa fl 06creNeHo 85 xeoprx o6ox craret,t ia 4oxyueHroeaHru iHSaprrou uriorap4a is sy6qerr,r Q nporrrou 60 4i6 nicnn MoMeHTy rocnirarisaqiT. KriHi'lHIta craryc, cTaH rap4ioreuo4ttHauirur ra auuipoaauHR pieHn qlrpxyrrorogoro N-KiHqeBoro $parMeHra [403K08010 Harpir,lypernrHoro renrrAy (NT-pro-MHVI-|) 6ynu oqiHeHi a 1-uy, Ha 21-uy i 60-ry 4o6y po3Br4TKy 3axBopoBaHHfl. AHaris orpruaHrx AaHilx roKa3aB, u.lo i3onuosaHe auuipoeauHn piaHn NT-pro-MHVI] e 1-uy go6y rocnirarisauii 4oaeorne 4oorru Ha4ir,tuo nepe46arnru riluoeipHicru BIHt4KHeHHr paHHb0r0 niclniHQaprrHor0 peMoflenoBaHHfl ceptlr i crcrori.rHoj gr.rcSyHrqii Il[J. l-lpr,t UboMy nporHocrrrHa qiHHicru apocraHHr piaHn NT-pro-MHVIl He 3anexafla ei4 iH4ercy HecnpilflTIrt4Br4x KniHieHl4x pesyrurarie GRACE irRxr<ocri loraruHoi KoHTpaKr[nbH0i4llceyHrqii. fliroruril peecrp rocrpl4x KopoHapHnx craHApoNrie 72 s eneeaqieo cerMeHra ST STIMUL: xapaKrepilcrilKa xBopr4x, opraHisaqin ve4rvuoi .qonoMoril Ha rocni- The pilot registry of acute coronary syndromes with ST segment elevation STIMUL: characteristics of patients and results of in-hospital treatment S.V. Valuyeva, V.l. Denysiuk ranbHoMy erani niryeauHn C.B. Banyeea, B.l.,Q,exncox - nirorHntt peocrp tocrpt4x KopoHapH[x cl,tu4potuia (IKC) s ereeaqien cerueura ST - e nepuLr,rrvr peecrpoBr4M gocri4xeHHRu e nepeg6arae TpIBane gaopirHe cnocTepexeHHfl. Mera 4arn rrtiHixo-aHa[4HecrilqHy xapaKTepucTt4Ky xBgpr4M s I-KC s ereaaqierc cetMeHTa STra oqiHrrr rricru Ha4auHR Me[[rHoiAonoM0Til HacereHHn y npoSinuHrx craqioHapaxraii ei4noai4Hicrb cyracHIM BilMotaM. V AocniAxeuHn 3anyreHo 1103 xaopr,tx s [KC, rocniranigoaaHilx y rap4iororirui ra r<apgioxipyprirHi craqioHapn BiHHuqi ra XueruHuquroro (3 qeHrpr) ai4 cirur 2008 no repeHr 2011 p. B o6crexeHrx xBopr4x ei4eHareHo Br4coKy nouilpeHicTb raKfix Sarropie pu314Ky, nr aprepianuxa rinepreHeir (76,61 %), rinepxonecreprueuin (20,85 %), oxr,rpiHHn (32,0 "/o), rypiHun (59,29 %), o6rRxeHa cna4roaicru (31 ,82%),6irsuicru nrrx e uo4rQiK0BaHIMt4. Pesynurarr peecrpy Br4flBr4flt4 Heai4noaipHicru opraHisaqii HaAaHHr ve4rvHoi [on0N4oril xBop14M s IKC s eneaaqierc cerueHra ST 4o ictrynrux peroueH4aqirl. STIMUL VrpaiHi, nrrtl - Ukrainian Journal of Cardiology 3/2012 Arepocxleporr4r.iHe ypaxeHHn eiHqeanx aprepii ra iueuiqHa xeopo6a cepLln y xBopr4x ua crcrevnril 13 79 Atherosclerosis of coronary arteries and ischemic heart disease in patients with systemic lupus erythematosus l,G. Matiyashchuk vepaouufi BoBqaK l.F. Marinu4yx Bil3Haqilrr yacrory i xapaxrep arepocKnepol4rHoro ypaxeHHn eixqearx aprepifi (BA) i acoqirlosaHoi g HilN iueNri,lnoi y xBopr4x Ha cncreuHnfi repaoHuil aoarax (CHB), 3anponoHyBarr paqioHaruHnri anroprrM 4iarHocrrru IXC y qiei xareropii xBopr4x. Br4sreHo pe3yflbraril ayroncii sa cerqifiHilrvu,r npoToKonaMl4 rI icropii xaopo6 33 noMepn[x, nxi crpaxganr ua CYB, ra 06cTexeH0 100 xaoprx Ha CYB.,[rr arRenexHR Kanbqr4Ho3y BA npoao4unr uyrurucniparuHy KoMn'nrepHyrourorpaQiro (MCKT),3 MeTo]o AiarHocrrrm IXC rpeguin-recr i crpec-exoxapgiorpaSirc s Ar4nipn4al4orol.0sHaxil arepocKnepo3y aoprr4 cnocrepiranra y 51,5 % noMepnilx oci6, BA y 39,4 %, creHorueHi ypaxeHHfl BA peecrpyaanr y KoxHoro n'flToro noMepnoro xBoporo. 3a 4aHuur MCKT xanuqrQiraqirc BA eilsHayeHo y 39 % xaopnx Ha ClB, cepeAHi 3HaeeHHr xanuqieeoro iHgercy ai,qnoai4anu cra6riil ranuqrQiraqii. CryniHu ranuqrSiraqii piannx 4irnnor BA sueHuyaaacn a rarifi nocnigoeHocri: nepeAHr Hnaxi4ua riflxa flieoi BA - croa6yp risoi BA - npasa BA orrHaora rirra nisoi BA. Ha niflcraei pesynuraria rpuox rrrero4ia Aocri[xeHHs 4iarnoe IXC gcraHoereHo y 21 xaoporo Ha CIB (53,8 % sia xinurocri xBopr4x 3 no3ilTr4BHr4Mr4 pe3ynbraTal4lr MCKT). Kninirni ogHarut IXC ai4eHararu a 11 xaopux. finn ceoeracnoro ennsneHHn IXC y xBopr4x Ha CtlB peroueH4osaHo rar[il aflroprrM fliarHocTr4Kt4: nx crpuHiHroanfi recr gnn giarHocruru arepocKnepo3y BA 4oqinuHo Br4Kopr4croayBar[ MeroA MCKT; y xBopr,rx 3 n03[rr4BH14M14 pe3yflbTaTaMu MCKT s ueron giarnocrnrn IXC cnifl ei,qflaearil nepeBary crpecexorapgiorpa$ii s,qunipilflaruonou yHacrigor anqoi inQopuarilsHocri qiei npo6n (96,2 %) nopiaHnHo a rpe4uir-recrou (55,3 %), Mera po6orr - xaopo6r,r cepqs (lXC) - - - flony.raqifiHa (apAioJr ofin / KaqecraeHHure ta KonilqecrBeHHbre xapaKTepilcruKr4 86 norpe6nenrR arKorors e rvpxcrofi nonyrrst-\vtn v nx ArHaMr4Ka: AaHHbre SnuEeMl/lonorrqecKoTo hccfleiloBaHVfl Population cardiology Quality and quantity characteristics of alcohol consumption in male population and their dynamics: data from the epidemiological surveys Ye.A. Kvasha E,A. Kaaula l-leru - usyruru oco6esHoctr,r crpyKrypbr norpe6reHun anKoronfl (racrora, o6reu, Hanrrru) y wyxrnH B Bo3pacTe 20-64 rer no ,qaHHbtM onilAeMiloaorneecKoro ilccnenoBaHufl 14 oqeHr4Tb.q[HaMHKy orr4x noKa3aTeneri sa 10-rerNflfi nepno4. [lpraurrru ynorpe6leHun aaKorolrbHbrx HanITKoB (AH) ycraHoareHbr B xo4e flByx oAHoMoMeHrHbrx 3n[fleMIonorr4eecKnx nccregoaaHrr,t cnyrarluoft eur6opru uyxruH 2064 rer r. Kilesa, gurnonHeHHbrx c r,rHTepBafloM a 10 ner. Korrrectgo o6cneAoaanHurx a 2000 r. cocTaBuro gg7, a s 2010 r. 1009. 3a '10 - rer ronu,iecrBo MyxyrlH, ynorpe6nnaurx AH a re,ieHre roAa, B qenoM yMeHbuJunocu (c 93,2 Ao 84,2 %, P<0,001), cyqecrBeHHo cHr43r4flocb cpeAHee KonreecrBo alrKorollfl B nepepacrere na qucrurr,r oraHon - (c (19,54t0,98) Ao (17,6010,10), P<0,05) r yMeHbulr4nacb flonn nilq, norpe6rnoqnx AH e [e6utroqHoM KorIrecTBe (c 36,9 Ao 31,9 %). BurRsreHHsre il3MeHeHr4fl xapaKTepHbr AnR Bcex Bo3pacrHbtx rpynn. Bo Bcex Bo3pacrHbrx rpynnax perilcTpr4pyror yBenilreHne Aon[ flfir.1, ynorpe6rnoqnx AH Hecronuxo pa3 B HeAeno t4lI exenHeBHo (a qelou c 26,8 Ao 31,8 %, P<0,05). HecNorpn Ha HaMernBul4ecfl no3rrtlBHbre r3MeHeHre rt,tna norpe6neHrn AH, Mn Myxqr4H VxpanHur ocraercn xapaKrepHbrM onr43oA[qecKoe ynorpe6reHue 6onuunx.qo3 KpenKoro aaKoronfl, ycunfiBa]oulee ero ponb rar Qarropa pncxa BblcoKoro ypoaHn o6u1eu l,l cepAeqHo-cocy4rcroil cMepTHocTr4 HaceneHfi F. Xropo6n l,riorcap,4a MorerynnpHuril uanepoH Hsp60: oco6eHHocrr ayror4MMyHHbrx pearqnil Lr oKcnpeccr4v npv EnnarallroHnoft rap4novnonarw fl.B. Pn6earo, rl.H. Kanycrnx, O.T. Poxxo, B.l,l. Eo6urr, fl.I1. Cr4opnr / Myocardial 93 diseases Molecular chaperon Hsp60: autoimmune reactions and myocardial expression peculiarities at dilated cardiomyopathy D.V. Riabenko, L.N. Kapustian, O.T. Rozhko, V.l. Bobyk, L.L. Sidorik r $opruupoaaHnn ayTo14MMyHHurx pearqnfi K uanepoHy Hsp60 npil flnnaraq[oHuofi rap4nouilonarilr ([KMn). B pa6ore 6stn ucnorreosaH GroEL npoKapiloTr4eecxmfi rouolor Hsp60 (rouorornrHocru > 50 %), o6pasqur ceKqiloHHoro narouopQororr4qecKoro Marepilafla M[oKap.qa aeBoro xenyAoqxa 6oruHurx [KMl-l r,r Tpex IpaKTileecKil 3IopoBbrx nrc4eil, norn6uLr4x B pe3ynbrare HeclacTHoro cnyran. KornrecrBeHHbre u3MeHeHilfl SKcnpeccu14 Hsp60 n ero ilpegcraareHur pe3ynbraTbn4ccne4oBaHufl oco6eHHocrefi oKcnpeccu14, fl0Kafl[3aqil[ - pefloKaa[3aq[to B KapA[Mr4or.I4Tax il3yearI c noMorlbr0 r,rrvrrvryHo6norrnHra. VpoeeHu ayroaHTilTen nporr,ra Hsp60 r4ccne.qoBafl[ c noMotlblo uero4a ELISA B cbrBoporKax 24 6onuHurx c IKMl-l c xpoHnrecxor,r cepAe,]H014 HeAocraroqHocrurc ll-ill SyurqnoHanuHbtx KraccoB no NYHA u 38 agopoaurx AoHopoB. BurRareHo, rr0 ypoBHr4 anrn-Hsp60 aHTrrefl xracca lgG r lgM a cbrBoporKax 6onuHurx c EKMI1 AocToBepHo He oTflt4ealrilcb 0r raKoBbrx a xonrponuHoil rpynne. Co4epxaHue Hsp60 B r[3arax rg rranerl cep4qa npr4 lKMl-l npeaurutaro KoHTpoflbHbte noKa3arenil HopMbr B 2,36 pasa. llpr srou KonrrecTBo 6enra Hsp60 B MnroxoHApranunorl cy6QpaKqhr npr AKMI-l na 66 % euruJe, a a UilTonlra3Me KapAiloMr,ror.lr4Toa - Ha 59 % nuxe, reM B cepflqax nfiq KoHTponbHori rpynnur. 14 Yxpaiucaxuil rcapqionorituuk xypnan 3/20 1 2 Cnoctepex(eHHe a flpaKruKu / Case report eQQernaenocrb BoccraHoBlreHr4fl t4 coxpaHeHre cil- 100 Efficacy of sinus rhythm restoration and preservation in HycoBoro pilrMa y 6orunurx c rpexnerHilM onn3ogoM patients with three-years long atrial flutter episodes rpeneraHilq npe4cepgril Yu.V. Zinchenko, S.V. Lizogub, M.R. lkorkin lO.B. 3un,{exro, C.B. Ilmsory6, M.P. hxopxrau Haur autnolHeHa 3neKTpocrt4Mynflut40HHafl Kapflil0BepcIr 6es npe4eapurenuHor,l SoHoaor,t aHrrapnrunrecxofi repannr y rpex naq[eHToB nph rpexnerHeM 3n[304e rl4llt4YH0l0 Tpe[eraHilr npe4cep4rti I runa HeuanaHH0ro reHe3a. Bceu naqreHraM BoccraHoBfleH crHycoaurrl prrN. [lpe4craBreHHble Klll4HilYecKile cnyrail HatnflAHo EoKa3brBarcT, yro reyeH[e riln[9Horo T[1 pa4nraluHo gT;tilraercfl 0T TaKTuKt4 BeAeHilfl 6oluHutx c Ol-l - KaK no BoccraHoBreHuo t/ coxpaHeHilo cr4HycoBoro pr4TMa, raK r no Heo6xo4r,r[40c14 14 cpoKaM np6Be4eHhfl aHT[KoatynflHTHoti repannu. Cle4oaareluHo, c qeflbto peuJeH[fl Bonpoca o 4aruHeilueyr raKTilKe rereHilr raxrx 6oluHurx Heo6xogruo npoBeAeHile KapA[oBepcfl 14, He3aBilct4M0 0T npoEoax[Tefl bH0cTt4 apilTM1414. / Ornngu PeuuH-aHrroreH3klHoBafl Reviews cilcreMa e rap4nanuuoil 105 Renin-angiotensin naronorilil. qacru 1 B.H. Koeanexro, T.B. Tanaeea, B.B. Eparycu system in cardiac pathology. part 1 V.N. Kovalenko, T.V. Talayeva, V.V. Bratus rpltrrrecruil aHan[3 .qaHHbrx coBpeMeHHot4 arreparypbr no npo6neue npIHtlilngB opraHr43auil[, SyHrquoHnpoaaHun petynflqilh aKT[BH0cTl4 peHilH-aHriloreH3ilHOB0f cl4cTeMbl, ee yYacr[fl B pa3BilTt4t4 eaxHetiuux Soprvr r<ap414oaacrylnpHori nar01o14t4 t4 3Har IM0cr4 KaK MilrueHil npI npoBe4eHu n $apuaxonorurecKilx BMeluarerbcrB. B o6aope fip0BeAeH I Berropnnfi aHaflis eneKrpoKapgiorpavra e ouiHqi 130 Vector analysis of electrocardiogram in evaluation of localization of stimulation lead during ventricular rorariaaqii crt4Myntotoqoro eneKrpoga npr eneKrpoxapgiocrrvynnqii runynov rie pacing F.B. Kxruroe, €.O. EinrancsKult, E.E. Kpaevyr, 8.fl . 3aneacuxrai, O.B. Pacnyrxnr G.V. Knyshov, Ye.O. Bilynskyi, B.B. Kravchuk, V.P. Zalevskyi, O.V. Rasputniak BerropHt'ttI aHanis EKI- y 12 eiAae4eHHflx flo3Boflfle oqiHrru uJnyHorKoBy rorarisaqin cTilMyaoororo eneKrpo.qa ra ar4gHarilr[ fioro M0xflilBe suiqeuur s uicqn no'larroaoi Sixcaqii, Uo e 0c06n[Bo aKTyaabHilM npr rap4iopecrnxpoHieaqifiHira repanii. B iAeani 6axaHo peecTpyBar[ EKI y 12 ai4ae4eHHnx nig rac irltnnaHraqii cruuynnropa i npornrov nicnnonepaqiilHor0 cnocTepexeHHn. AHanis g.qHgKaHaflbuoro EK[-ai4aeAeHHfl Moxe np[3Becr[ Ao noM[aKoBol oqiHrn cruNynnqii, ToMy nepcneKr[BHr,lM e crB6peHHq nporpaua-ropie, rqo BKfl mramrb peecrpaqirc 1 2-raHanusoi EK[. / lnformation luQopma4in Pegonpqis Xl Kral'ecuroro Kypcy 3 KopoHapHrx eacxynnpueaqii Kuia,26-27 reirr-rn 2012 pe- 140 Resolution of Xl Kyiv Course on coronary revascuIarization Kyiv,26-27 Aprit 2OlZ pory Hexponor Ceprii Mraronafi oerr llonuao,qa (1953-2012) / Obituary 142 Sergii Mykolayovych Polyvoda (1953-2012) @ @ Yrpaiucuxraft rapgiororivur ia xypaaa, 201 2 TOB n9ereepta xannn", 2012