WELCOME TO THE 12TH LURN RETREAT APRIL 15‐16, 2015 YSTAD SALTSJÖBAD, YSTAD ORGANIZING COMMITTEE: Gunilla Westergren‐Thorsson, Leif Bjermer, Arne Egesten, Jonas Erjefält, Claes‐Göran Löfdahl, Roland Andersson, Kristina Rydell‐Törmänen, Marianne Person, Jenny Karlsson and Agneta Hult PROGRAM COORDINATOR: Kristina Rydell‐Törmänen SUPPORTED BY: The Sandberg foundation ALUMNI HONORARY SANDBERG LECTURERS 2014 Professor Rachel Chambers, University College, London, UK Professor Gunnar Nilsson, Karolinska Insitutet, Stockholm, Sweden Professor Peter Sterk, AMC, Amsterdam, The Netherlands Dr Patrick Mallia, Imperial College, London, UK 2013 Professor Oliver Eickelberg, Ludwig‐Maximilians‐Universität and Helmholtz Zentrum, München, Germany Professor Pieter S Hiemstra, Leiden University, Leiden, The Netherlands Professor Guy G Brusselle, Ghent University Hospital and Ghent University, Ghent, Belgium Dr Andrew McKenzie, University of Cambridge, Cambridge, UK 2012 Professor James C. Hogg, iCAPTURE Center, St. Paul´s Hospital, VA, Canada 2011 Professor Dirkje Postma, University of Groningen, Groningen, the Netherlands SANDBERG AWARDEES 2014 Professor Michael Benson, Linköping University, Linköping, Sweden 2013 ‐ 2012 Professors Anders Blomberg and Thomas Sandström, Umeå University, Umeå, Sweden 2011 Professors Anders Eklund and Johan Grünewald, Karolinska Institutet, Stockholm, Sweden YOUNG INVESTIGATOR AWARDEES 2014 Mandy Menzel, Lund University, Lund, Sweden Henning Svensson, Lund University, Lund, Sweden Maria Weitoft, Lund University, Lund, Sweden 2013 Yuan Xu, Karolinska Institutet, Stockholm, Sweden Michiko Mori, Lund University, Lund, Sweden Sara Rolandsson, Lund University, Lund, Sweden Jenny Calvén, Lund University 2012 Emil Tykesson, Lund University, Lund, Sweden 2011 Abraham Roos, Karolinska Institutet, Stockholm, Sweden DAY 1 – WEDNESDAY 15TH APRIL 9.30‐10.00 Arrival and Coffee break Session A – Welcome and introduction to LURN 10.00‐10.15 Welcome and introduction – Professor Gunilla Westergren‐Thorsson, Lund University, Lund 10.15‐10.30 LURN 2015 – Kristina Rydell‐Törmänen, Lund University, Lund Univeristy Session B – Idiopathic lung diseases – diagnosis and treatment CHAIRMEN: 10.30‐11.10 Professor Magnus Sköld, Md, PhD (Karolinska Institutet, Stockholm, Sweden) Diagnosis and treatment strategies of IPF in EU in general and Sweden in particular 11.10‐11.20 Discussion 11.20‐12.00 Professor Leif Bjermer, MD, PhD (Lund University and Skåne University Hospital) Severe asthma – diagnosis and clinical management 12.00‐12.10 Discussion 12.10‐13.10 Lunch Session C – New aspects of COPD CHAIRMEN: 13.15‐13.55 Susanne Gabrielsson, PhD (Karolinska Institutet, Stockholm, Sweden) Exosomes in COPD 13.55‐14.05 Discussion 14.05‐14.15 Kasetty Gopinath (Lund University, Lund, Sweden) The role of osteopontin in COPD 14.15‐14.20 Discussion 14.20‐14.30 Julie Weidner, PhD (Lund University, Lund, Sweden) Extracellular matrix modifying enzymes in COPD 14.30‐14.35 Discussion 14.35‐15.00 Coffee and check in Session D ‐ New angles on asthma pathology and therapy CHAIRMEN: 15.00‐15.40 Professor Sven‐Erik Dahlen, MD, PhD (Karolinska Insitutet, Stockholm, Sweden) Bitter‐taste receptors in asthma 15.40‐15.50 Discussion 15.50‐16.00 Mandy Menzel (Lund University, Lund, Sweden) Macrolide treatment in asthma 16.00‐16.05 Discussion 16.05‐16.15 Hamid Akbarshahi, MD, PhD (Lund University, Lund, Sweden) Role of PRRs signaling in an experimental model of asthma exacerbation Session E – Poster presentation 16.20‐17.15 Authors will be present for individual discussions Posters will be on display during the rest of the retreat 19.30 Dinner DAY 2 – THURSDAY 16TH APRIL Session F – Stem cells in lung development and pathogenesis CHAIRMEN: 8.15‐8.55 Professor Melanie Königshoff, MD, PhD (Ludwig‐Maximilians‐Universität and Helmholtz Zentrum, München, Germany) Stem cells/progenitors and embryonic signaling in lung diseases 8.55‐9.05 Discussion 9.05‐9.20 Mattias Magnusson, PhD (Lund University, Lund, Sweden) Developing stem cell based therapies for blood and pulmonary disorders 9.20‐9.25 Discussion 9.25‐9.35 Sara Rolandsson (Lund University, Lund, Sweden) MSC in regeneration 9.35‐9.40 9.50‐10.20 Discussion Coffee and check out Session G – Cell and tissue remodelling and regeneration CHAIRMEN: 10.20‐11.00 Professor Reinoud Gosens, PhD (University of Groningen, Groningen, the Netherlands) Acetylecholine in chronic inflammation and airway remodelling 11.00‐11.10 Discussion 11.10‐11.30 Professor Mattias Belting, MD,PhD (Lund University, Lund, Sweden) Cancer cells do not act alone ‐ the tumor microenvironment 11.30‐11.35 Discussion 11.35‐11.45 Emma Åhrman, PhD (Lund University, Lund, Sweden) The Lung Proteome 11.45‐11.50 Discussion 11.50‐12.00 Ulf Hedström (AstraZeneca, Mölndal, Lund University, Lund, Sweden) Title TBA 12.00‐12.05 Discussion 12.10‐13.10 Lunch Session H – Young Investigator award and Honorary lecture 13.10‐13.15 13.15‐13.45 Young Investigator Award “How I became a successful scientist” Short talks from Honorary Sandberg Lecturers; Professor Magnus Sköld Professor Melanie Königshoff Professor Reinoud Gosens 13.45‐14.15 PARTICIPANTS Coffee and departure